@article{09fc67aa80ef4fc19b2f650d59612af1,
title = "Motion corrected silent ZTE neuroimaging",
abstract = "Purpose: To develop self-navigated motion correction for 3D silent zero echo time (ZTE) based neuroimaging and characterize its performance for different types of head motion. Methods: The proposed method termed MERLIN (Motion Estimation & Retrospective correction Leveraging Interleaved Navigators) achieves self-navigation by using interleaved 3D phyllotaxis k-space sampling. Low resolution navigator images are reconstructed continuously throughout the ZTE acquisition using a sliding window and co-registered in image space relative to a fixed reference position. Rigid body motion corrections are then applied retrospectively to the k-space trajectory and raw data and reconstructed into a final, high-resolution ZTE image. Results: MERLIN demonstrated successful and consistent motion correction for magnetization prepared ZTE images for a range of different instructed motion paradigms. The acoustic noise response of the self-navigated phyllotaxis trajectory was found to be only slightly above ambient noise levels (<4 dBA). Conclusion: Silent ZTE imaging combined with MERLIN addresses two major challenges intrinsic to MRI (i.e., subject motion and acoustic noise) in a synergistic and integrated manner without increase in scan time and thereby forms a versatile and powerful framework for clinical and research MR neuroimaging applications.",
author = "Emil Ljungberg and Wood, {Tobias C} and Solana, {Ana Beatriz} and Williams, {Steven C R} and Barker, {Gareth J} and Florian Wiesinger",
note = "Funding Information: This work was supported by the Wellcome/EPSRC Centre for Medical Engineering [WT 203148/Z/16/Z] and GE Healthcare. It represents independent research part funded by the NIHR‐Wellcome Trust King's Clinical Research Facility and the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. F. Wiesinger and A.B. Solana are employees of General Electric Healthcare. Funding Information: information Wellcome/EPSRC Centre for Medical Engineering, [WT 203148/Z/16/Z]; National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, NIHR-Wellcome Trust King's Clinical Research Facility, GE HealthcareThis work was supported by the Wellcome/EPSRC Centre for Medical Engineering [WT 203148/Z/16/Z] and GE Healthcare. It represents independent research part funded by the NIHR-Wellcome Trust King's Clinical Research Facility and the National Institute for Health Research (NIHR) Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. F. Wiesinger and A.B. Solana are employees of General Electric Healthcare. Publisher Copyright: {\textcopyright} 2022 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.",
year = "2022",
month = jul,
doi = "10.1002/mrm.29201",
language = "English",
volume = "88",
pages = "195--210",
journal = "Magnetic Resonance in Medicine",
issn = "0740-3194",
publisher = "WILEY-BLACKWELL",
number = "1",
}