TY - JOUR
T1 - ‘My dad was like “it's your brain, what are you doing?”’: Participant experiences of repetitive transcranial magnetic stimulation treatment in severe enduring anorexia nervosa
AU - Dalton, Bethan
AU - Austin, Amelia
AU - Ching, Brian C.F.
AU - Potterton, Rachel
AU - McClelland, Jess
AU - Bartholdy, Savani
AU - Kekic, Maria
AU - Campbell, Iain
AU - Schmidt, Ulrike
N1 - Funding Information:
We would like to thank the individuals who participated in this study for their time and commitment and our patient and public involvement advisors for their valuable feedback. This work was supported by a National Institute for Health Research (NIHR) Research for Patient Benefit (RfPB) grant (Reference Number PB‐PG‐1013‐32049) and Infrastructure Support for Pilot studies from the NIHR Biomedical Research Centre (BRC) at South London and Maudsley NHS Foundation Trust (SLaM) and King’s College London (KCL). This study was also supported by the United Kingdom Clinical Research Collaboration‐registered King's Clinical Trials Unit at King's Health Partners, which is part‐funded by the NIHR BRC for Mental Health at SLaM and KCL and the NIHR Evaluation, Trials and Studies Coordinating Centre. Amelia Austin is supported by a KCL Postgraduate Research Scholarship. Rachel Potterton is supported by an NIHR RfPB grant (Reference Number NIHR201175). Ulrike Schmidt and Iain C. Campbell receive salary support from the NIHR Mental Health BRC at SLaM NHS Foundation Trust and KCL. Ulrike Schmidt is supported by an NIHR Senior Investigator Award. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.
Publisher Copyright:
© 2022 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.
PY - 2022/5
Y1 - 2022/5
N2 - Objective: Repetitive transcranial magnetic stimulation (rTMS) is a promising emerging treatment for anorexia nervosa (AN). However, to date, patients' views and experiences of this treatment have not been fully explored. To assess these, we integrated a qualitative study into a feasibility randomised controlled trial of rTMS in individuals with severe enduring AN. Method: Twenty-nine (of 34) trial participants contributed to this study. Semi-structured interviews were conducted 3-months following the completion of rTMS treatment (4-months post-randomisation), prior to unblinding. Transcripts were analysed using content analysis. Results: rTMS was deemed an acceptable but time-consuming treatment. Many emphasised how their lives had changed to some extent during, but mainly after treatment by making them more positive, open-minded, flexible and willing to try new things in relation to their AN and other aspects of their lives. Conclusions: These qualitative data will be valuable in shaping participant information, recruitment and planning of future large-scale trials of rTMS in AN. Trial Registration: ISRCTN14329415, registered 23rd July 2015, https://www.isrctn.com/ISRCTN14329415.
AB - Objective: Repetitive transcranial magnetic stimulation (rTMS) is a promising emerging treatment for anorexia nervosa (AN). However, to date, patients' views and experiences of this treatment have not been fully explored. To assess these, we integrated a qualitative study into a feasibility randomised controlled trial of rTMS in individuals with severe enduring AN. Method: Twenty-nine (of 34) trial participants contributed to this study. Semi-structured interviews were conducted 3-months following the completion of rTMS treatment (4-months post-randomisation), prior to unblinding. Transcripts were analysed using content analysis. Results: rTMS was deemed an acceptable but time-consuming treatment. Many emphasised how their lives had changed to some extent during, but mainly after treatment by making them more positive, open-minded, flexible and willing to try new things in relation to their AN and other aspects of their lives. Conclusions: These qualitative data will be valuable in shaping participant information, recruitment and planning of future large-scale trials of rTMS in AN. Trial Registration: ISRCTN14329415, registered 23rd July 2015, https://www.isrctn.com/ISRCTN14329415.
UR - http://www.scopus.com/inward/record.url?scp=85124513199&partnerID=8YFLogxK
U2 - 10.1002/erv.2890
DO - 10.1002/erv.2890
M3 - Article
SN - 1072-4133
VL - 30
SP - 237
EP - 249
JO - European Eating Disorders Review
JF - European Eating Disorders Review
IS - 3
ER -