TY - JOUR
T1 - Nicotinamide N-methyltransferase in health and disease, with special reference to cancer
AU - Ramsden, David B.
AU - Waring, RH
AU - Barlow, David John
AU - Parsons, Richard Bramwell
PY - 2017
Y1 - 2017
N2 - Over the past decade, the roles of nicotinamide N-methyltransferase and its product 1-methyl nicotinamide have emerged from playing merely minor roles in phase 2 xenobiotic metabolism as actors in some of the most important scenes of human life. In this review, the structures of the gene, messenger RNA, and protein are discussed, together with the role of the enzyme in many of the common cancers that afflict people today.
AB - Over the past decade, the roles of nicotinamide N-methyltransferase and its product 1-methyl nicotinamide have emerged from playing merely minor roles in phase 2 xenobiotic metabolism as actors in some of the most important scenes of human life. In this review, the structures of the gene, messenger RNA, and protein are discussed, together with the role of the enzyme in many of the common cancers that afflict people today.
UR - http://www.scopus.com/inward/record.url?scp=85045007990&partnerID=8YFLogxK
U2 - 10.1177/1178646917691739
DO - 10.1177/1178646917691739
M3 - Article
VL - 10
SP - 1
EP - 19
JO - International Journal of Tryptophan Research
JF - International Journal of Tryptophan Research
ER -
