Outcome of children with sickle cell disease admitted to intensive care: a single institution experience

Jack L. Bartram; Swee L. Thein; Kate Gardner; Yaya Egberongbe; Pam D'Silva; Sue Height; Moira Dick; Sandra O'Driscoll; David C. Rees

doi:10.1111/j.1365-2141.2010.08272.x

Outcome of children with sickle cell disease admitted to intensive care: a single institution experience

Jack L. Bartram, Swee L. Thein, Kate Gardner, Yaya Egberongbe, Pam D'Silva, Sue Height, Moira Dick, Sandra O'Driscoll, David C. Rees

Kings Coll Hosp

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Abstract

We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King's College Hospital between January 2000 and December 2008. Forty-six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7 6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.

Original language	English
Pages (from-to)	614-617
Number of pages	4
Journal	British Journal of Haematology
Volume	150
Issue number	5
DOIs	https://doi.org/10.1111/j.1365-2141.2010.08272.x
Publication status	Published - Sept 2010

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10.1111/j.1365-2141.2010.08272.x

Outcome of children with_BATRAM_Accepted 28Apr2010_GOLD VoRFinal published version, 60.3 KBLicence: CC BY

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abstract = "We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King's College Hospital between January 2000 and December 2008. Forty-six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7 6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.",

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AU - Bartram, Jack L.

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AU - Gardner, Kate

AU - Egberongbe, Yaya

AU - D'Silva, Pam

AU - Height, Sue

AU - Dick, Moira

AU - O'Driscoll, Sandra

AU - Rees, David C.

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N2 - We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King's College Hospital between January 2000 and December 2008. Forty-six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7 6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.

AB - We retrospectively audited children with sickle cell disease (SCD) admitted to paediatric intensive care (PICU) at King's College Hospital between January 2000 and December 2008. Forty-six children with SCD were admitted, on 49 separate occasions. Ages ranged from 4 months to 15 years (median 7 6 years). Three children died in PICU, however two presented to hospital in cardiorespiratory arrest; overall mortality was 6%. The most common reason for admission was acute chest syndrome (43%). 88% of admissions required blood transfusion, of which 74% had exchange blood transfusions. The mortality among children with SCD admitted to PICU is low.

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DO - 10.1111/j.1365-2141.2010.08272.x

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JO - British Journal of Haematology

JF - British Journal of Haematology

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ER -

Outcome of children with sickle cell disease admitted to intensive care: a single institution experience

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