Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data

Z Lim; A Pagliuca; S Simpson; S Cottam; M Ervine; A Y L Ho; S Devereux; G J Mufti

doi:10.1111/j.1365-2141.2006.06440.x

Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data

Z Lim, A Pagliuca, S Simpson, S Cottam, M Ervine, A Y L Ho, S Devereux, G J Mufti

King's College London

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The outcomes of 55 consecutive haemato-oncology patients admitted to the intensive care unit (ICU) were retrospectively analysed. Twenty-eight patients were admitted following haemopoietic stem cell transplantation (HSCT). Thirty-nine patients were admitted with respiratory failure, and all patients required respiratory support. Seventeen patients survived to be discharged from ICU, with an actuarial 1-year survival of 18%. Overall survival between patients who received intensive chemotherapy and those who underwent allogeneic HSCT was not significantly different (19% vs. 10%, P = 0.19). None of the nine myeloablative HSCT recipients survived (median survival: 9 d). Six of the 15 reduced-intensity conditioned HSCT recipients survived beyond 1 year (median survival: 1050 d, range: 438-1437)

Original language	English
Pages (from-to)	448 - 450
Number of pages	3
Journal	British Journal of Haematology
Volume	136
Issue number	3
DOIs	https://doi.org/10.1111/j.1365-2141.2006.06440.x
Publication status	Published - Feb 2007

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Lim, Z., Pagliuca, A., Simpson, S., Cottam, S., Ervine, M., Ho, A. Y. L., Devereux, S., & Mufti, G. J. (2007). Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data. British Journal of Haematology, 136(3), 448 - 450. https://doi.org/10.1111/j.1365-2141.2006.06440.x

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abstract = "The outcomes of 55 consecutive haemato-oncology patients admitted to the intensive care unit (ICU) were retrospectively analysed. Twenty-eight patients were admitted following haemopoietic stem cell transplantation (HSCT). Thirty-nine patients were admitted with respiratory failure, and all patients required respiratory support. Seventeen patients survived to be discharged from ICU, with an actuarial 1-year survival of 18%. Overall survival between patients who received intensive chemotherapy and those who underwent allogeneic HSCT was not significantly different (19% vs. 10%, P = 0.19). None of the nine myeloablative HSCT recipients survived (median survival: 9 d). Six of the 15 reduced-intensity conditioned HSCT recipients survived beyond 1 year (median survival: 1050 d, range: 438-1437)",

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Lim, Z, Pagliuca, A, Simpson, S, Cottam, S, Ervine, M, Ho, AYL, Devereux, S & Mufti, GJ 2007, 'Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data', British Journal of Haematology, vol. 136, no. 3, pp. 448 - 450. https://doi.org/10.1111/j.1365-2141.2006.06440.x

TY - JOUR

T1 - Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data

AU - Lim, Z

AU - Pagliuca, A

AU - Simpson, S

AU - Cottam, S

AU - Ervine, M

AU - Ho, A Y L

AU - Devereux, S

AU - Mufti, G J

PY - 2007/2

Y1 - 2007/2

N2 - The outcomes of 55 consecutive haemato-oncology patients admitted to the intensive care unit (ICU) were retrospectively analysed. Twenty-eight patients were admitted following haemopoietic stem cell transplantation (HSCT). Thirty-nine patients were admitted with respiratory failure, and all patients required respiratory support. Seventeen patients survived to be discharged from ICU, with an actuarial 1-year survival of 18%. Overall survival between patients who received intensive chemotherapy and those who underwent allogeneic HSCT was not significantly different (19% vs. 10%, P = 0.19). None of the nine myeloablative HSCT recipients survived (median survival: 9 d). Six of the 15 reduced-intensity conditioned HSCT recipients survived beyond 1 year (median survival: 1050 d, range: 438-1437)

AB - The outcomes of 55 consecutive haemato-oncology patients admitted to the intensive care unit (ICU) were retrospectively analysed. Twenty-eight patients were admitted following haemopoietic stem cell transplantation (HSCT). Thirty-nine patients were admitted with respiratory failure, and all patients required respiratory support. Seventeen patients survived to be discharged from ICU, with an actuarial 1-year survival of 18%. Overall survival between patients who received intensive chemotherapy and those who underwent allogeneic HSCT was not significantly different (19% vs. 10%, P = 0.19). None of the nine myeloablative HSCT recipients survived (median survival: 9 d). Six of the 15 reduced-intensity conditioned HSCT recipients survived beyond 1 year (median survival: 1050 d, range: 438-1437)

U2 - 10.1111/j.1365-2141.2006.06440.x

DO - 10.1111/j.1365-2141.2006.06440.x

M3 - Article

SN - 1365-2141

VL - 136

SP - 448

EP - 450

JO - British Journal of Haematology

JF - British Journal of Haematology

IS - 3

ER -

Outcomes of patients with haematological malignancies admitted to intensive care unit. A comparative review of allogeneic haematopoietic stem cell transplantation data

Abstract

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