Phaeochromcytoma crisis

B. C. Whitelaw; J. K. Prague; O. G. Mustafa; K-M. Schulte; P. A. Hopkins; J. A. Gilbert; A. M. McGregor; S. J. B. Aylwin

doi:10.1111/cen.12324

Phaeochromcytoma crisis

B. C. Whitelaw^*, J. K. Prague, O. G. Mustafa, K-M. Schulte, P. A. Hopkins, J. A. Gilbert, A. M. McGregor, S. J. B. Aylwin

^*Corresponding author for this work

King's College Hospital

Research output: Contribution to journal › Article › peer-review

89 Citations (Scopus)

Abstract

Phaeochromcytoma crisis is an endocrine emergency associated with significant mortality. There is little published guidance on the management of Phaeochromcytoma crisis. This clinical practice update summarizes the relevant published literature, including a detailed review of cases published in the past 5years, and a proposed classification system. We review the recommended management of Phaeochromcytoma crisis including the use of alpha-blockade, which is strongly associated with survival of a crisis. Mechanical circulatory supportive therapy (including intra-aortic balloon pump or extra-corporeal membrane oxygenation) is strongly recommended for patients with sustained hypotension. Surgical intervention should be deferred until medical stabilization is achieved.

Original language	English
Pages (from-to)	13-22
Number of pages	10
Journal	Clinical endocrinology
Volume	80
Issue number	1
DOIs	https://doi.org/10.1111/cen.12324
Publication status	Published - Jan 2014

Keywords

INTERLEUKIN-6 PRODUCING PHEOCHROMOCYTOMA
EXTRACORPOREAL MEMBRANE-OXYGENATION
CARDIOGENIC-SHOCK
HYPERTENSIVE CRISIS
SEPTIC SHOCK
UNDIAGNOSED PHEOCHROMOCYTOMA
PERIOPERATIVE MANAGEMENT
CARDIOPULMONARY BYPASS
INFLAMMATORY SYNDROME
MULTISYSTEM CRISIS

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10.1111/cen.12324

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title = "Phaeochromcytoma crisis",

abstract = "Phaeochromcytoma crisis is an endocrine emergency associated with significant mortality. There is little published guidance on the management of Phaeochromcytoma crisis. This clinical practice update summarizes the relevant published literature, including a detailed review of cases published in the past 5years, and a proposed classification system. We review the recommended management of Phaeochromcytoma crisis including the use of alpha-blockade, which is strongly associated with survival of a crisis. Mechanical circulatory supportive therapy (including intra-aortic balloon pump or extra-corporeal membrane oxygenation) is strongly recommended for patients with sustained hypotension. Surgical intervention should be deferred until medical stabilization is achieved.",

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author = "Whitelaw, {B. C.} and Prague, {J. K.} and Mustafa, {O. G.} and K-M. Schulte and Hopkins, {P. A.} and Gilbert, {J. A.} and McGregor, {A. M.} and Aylwin, {S. J. B.}",

year = "2014",

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doi = "10.1111/cen.12324",

language = "English",

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AU - Prague, J. K.

AU - Mustafa, O. G.

AU - Schulte, K-M.

AU - Hopkins, P. A.

AU - Gilbert, J. A.

AU - McGregor, A. M.

AU - Aylwin , S. J. B.

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KW - HYPERTENSIVE CRISIS

KW - SEPTIC SHOCK

KW - UNDIAGNOSED PHEOCHROMOCYTOMA

KW - PERIOPERATIVE MANAGEMENT

KW - CARDIOPULMONARY BYPASS

KW - INFLAMMATORY SYNDROME

KW - MULTISYSTEM CRISIS

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SP - 13

EP - 22

JO - Clinical endocrinology

JF - Clinical endocrinology

IS - 1

ER -

Phaeochromcytoma crisis

Abstract

Keywords

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