Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group

Arjan A. van de Loosdrecht; Robin Ireland; Wolfgang Kern; Matteo G. Della Porta; Canan Alhan; Jan Sebastian Balleisen; Peter Bettelheim; David T. Bowen; Kate Burbury; Lisa Eidenschink; Mario Cazzola; Spencer S. C. Chu; Matthew Cullen; Jevon A. Cutler; Angelika M. Drager; Jean Feuillard; Pierre Fenaux; Patricia Font; Ulrich Germing; Detlef Haase; Eva Hellstrom-Lindberg; Ulrika Johansson; Shahram Kordasti; Michael R. Loken; Luca Malcovati; Jeroen G. te Marvelde; Sergio Matarraz; Timothy Milne; Bijan Moshaver; Ghulam J. Mufti; Veselka Nikolova; Kiyoyuki Ogata; Uta Oelschlaegel; Alberto Orfao; Gert J. Ossenkoppele; Anna Porwit; Uwe Platzbecker; Frank Preijers; Katherina Psarra; Stephen J. Richards; Dolores Subira; John F. Seymour; Vicky Tindell; Teresa Vallespi; Peter Valent; Vincent H. J. van der Velden; Denise A. Wells; Theo M. de Witte; Florian Zettl; Marie C. Bene; Theresia M. Westers

doi:10.3109/10428194.2012.718341

Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group

Arjan A. van de Loosdrecht^*, Robin Ireland, Wolfgang Kern, Matteo G. Della Porta, Canan Alhan, Jan Sebastian Balleisen, Peter Bettelheim, David T. Bowen, Kate Burbury, Lisa Eidenschink, Mario Cazzola, Spencer S. C. Chu, Matthew Cullen, Jevon A. Cutler, Angelika M. Drager, Jean Feuillard, Pierre Fenaux, Patricia Font, Ulrich Germing, Detlef HaaseEva Hellstrom-Lindberg, Ulrika Johansson, Shahram Kordasti, Michael R. Loken, Luca Malcovati, Jeroen G. te Marvelde, Sergio Matarraz, Timothy Milne, Bijan Moshaver, Ghulam J. Mufti, Veselka Nikolova, Kiyoyuki Ogata, Uta Oelschlaegel, Alberto Orfao, Gert J. Ossenkoppele, Anna Porwit, Uwe Platzbecker, Frank Preijers, Katherina Psarra, Stephen J. Richards, Dolores Subira, John F. Seymour, Vicky Tindell, Teresa Vallespi, Peter Valent, Vincent H. J. van der Velden, Denise A. Wells, Theo M. de Witte, Florian Zettl, Marie C. Bene, Theresia M. Westers

^*Corresponding author for this work

Research output: Contribution to journal › Literature review › peer-review

63 Citations (Scopus)

Abstract

An international working group within the European LeukemiaNet gathered, aiming to determine the role of flow cytometry (FC) in myelodysplastic syndromes (MDS). It was agreed that FC has a substantial application in disease characterization, diagnosis and prognosis. FC may also be useful in predicting treatment responses and monitoring novel and standard therapeutic regimens. In this article the rationale is discussed that flow cytometry should be integrated as a part of diagnostic and prognostic scoring systems in MDS.

Original language	English
Pages (from-to)	472-475
Number of pages	4
Journal	Leukemia and Lymphoma
Volume	54
Issue number	3
DOIs	https://doi.org/10.3109/10428194.2012.718341
Publication status	Published - Mar 2013

Keywords

Myelodysplastic syndromes
flow cytometry
ELN
consensus
PROGNOSTIC SCORING SYSTEM
SYNDROMES MDS
BONE-MARROW
T-CELLS
MUTATIONS
DIAGNOSIS
VALIDATION
UTILITY
STANDARDIZATION
IMMUNOPHENOTYPE

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10.3109/10428194.2012.718341

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van de Loosdrecht, A. A., Ireland, R., Kern, W., Della Porta, M. G., Alhan, C., Balleisen, J. S., Bettelheim, P., Bowen, D. T., Burbury, K., Eidenschink, L., Cazzola, M., Chu, S. S. C., Cullen, M., Cutler, J. A., Drager, A. M., Feuillard, J., Fenaux, P., Font, P., Germing, U., ... Westers, T. M. (2013). Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group. Leukemia and Lymphoma, 54(3), 472-475. https://doi.org/10.3109/10428194.2012.718341

@article{e9c49e6187ba4f2e86d9ea6403a0adea,

title = "Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group",

abstract = "An international working group within the European LeukemiaNet gathered, aiming to determine the role of flow cytometry (FC) in myelodysplastic syndromes (MDS). It was agreed that FC has a substantial application in disease characterization, diagnosis and prognosis. FC may also be useful in predicting treatment responses and monitoring novel and standard therapeutic regimens. In this article the rationale is discussed that flow cytometry should be integrated as a part of diagnostic and prognostic scoring systems in MDS.",

keywords = "Myelodysplastic syndromes, flow cytometry, ELN, consensus, PROGNOSTIC SCORING SYSTEM, SYNDROMES MDS, BONE-MARROW, T-CELLS, MUTATIONS, DIAGNOSIS, VALIDATION, UTILITY, STANDARDIZATION, IMMUNOPHENOTYPE",

author = "{van de Loosdrecht}, {Arjan A.} and Robin Ireland and Wolfgang Kern and {Della Porta}, {Matteo G.} and Canan Alhan and Balleisen, {Jan Sebastian} and Peter Bettelheim and Bowen, {David T.} and Kate Burbury and Lisa Eidenschink and Mario Cazzola and Chu, {Spencer S. C.} and Matthew Cullen and Cutler, {Jevon A.} and Drager, {Angelika M.} and Jean Feuillard and Pierre Fenaux and Patricia Font and Ulrich Germing and Detlef Haase and Eva Hellstrom-Lindberg and Ulrika Johansson and Shahram Kordasti and Loken, {Michael R.} and Luca Malcovati and {te Marvelde}, {Jeroen G.} and Sergio Matarraz and Timothy Milne and Bijan Moshaver and Mufti, {Ghulam J.} and Veselka Nikolova and Kiyoyuki Ogata and Uta Oelschlaegel and Alberto Orfao and Ossenkoppele, {Gert J.} and Anna Porwit and Uwe Platzbecker and Frank Preijers and Katherina Psarra and Richards, {Stephen J.} and Dolores Subira and Seymour, {John F.} and Vicky Tindell and Teresa Vallespi and Peter Valent and {van der Velden}, {Vincent H. J.} and Wells, {Denise A.} and {de Witte}, {Theo M.} and Florian Zettl and Bene, {Marie C.} and Westers, {Theresia M.}",

year = "2013",

month = mar,

doi = "10.3109/10428194.2012.718341",

language = "English",

volume = "54",

pages = "472--475",

journal = "Leukemia and Lymphoma",

issn = "1042-8194",

publisher = "Informa Healthcare",

number = "3",

}

van de Loosdrecht, AA, Ireland, R, Kern, W, Della Porta, MG, Alhan, C, Balleisen, JS, Bettelheim, P, Bowen, DT, Burbury, K, Eidenschink, L, Cazzola, M, Chu, SSC, Cullen, M, Cutler, JA, Drager, AM, Feuillard, J, Fenaux, P, Font, P, Germing, U, Haase, D, Hellstrom-Lindberg, E, Johansson, U, Kordasti, S, Loken, MR, Malcovati, L, te Marvelde, JG, Matarraz, S, Milne, T, Moshaver, B, Mufti, GJ, Nikolova, V, Ogata, K, Oelschlaegel, U, Orfao, A, Ossenkoppele, GJ, Porwit, A, Platzbecker, U, Preijers, F, Psarra, K, Richards, SJ, Subira, D, Seymour, JF, Tindell, V, Vallespi, T, Valent, P, van der Velden, VHJ, Wells, DA, de Witte, TM, Zettl, F, Bene, MC & Westers, TM 2013, 'Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group', Leukemia and Lymphoma, vol. 54, no. 3, pp. 472-475. https://doi.org/10.3109/10428194.2012.718341

Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group. / van de Loosdrecht, Arjan A.; Ireland, Robin; Kern, Wolfgang et al.
In: Leukemia and Lymphoma, Vol. 54, No. 3, 03.2013, p. 472-475.

Research output: Contribution to journal › Literature review › peer-review

TY - JOUR

T1 - Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes

T2 - position paper of an International Consortium and the European LeukemiaNet Working Group

AU - van de Loosdrecht, Arjan A.

AU - Ireland, Robin

AU - Kern, Wolfgang

AU - Della Porta, Matteo G.

AU - Alhan, Canan

AU - Balleisen, Jan Sebastian

AU - Bettelheim, Peter

AU - Bowen, David T.

AU - Burbury, Kate

AU - Eidenschink, Lisa

AU - Cazzola, Mario

AU - Chu, Spencer S. C.

AU - Cullen, Matthew

AU - Cutler, Jevon A.

AU - Drager, Angelika M.

AU - Feuillard, Jean

AU - Fenaux, Pierre

AU - Font, Patricia

AU - Germing, Ulrich

AU - Haase, Detlef

AU - Hellstrom-Lindberg, Eva

AU - Johansson, Ulrika

AU - Kordasti, Shahram

AU - Loken, Michael R.

AU - Malcovati, Luca

AU - te Marvelde, Jeroen G.

AU - Matarraz, Sergio

AU - Milne, Timothy

AU - Moshaver, Bijan

AU - Mufti, Ghulam J.

AU - Nikolova, Veselka

AU - Ogata, Kiyoyuki

AU - Oelschlaegel, Uta

AU - Orfao, Alberto

AU - Ossenkoppele, Gert J.

AU - Porwit, Anna

AU - Platzbecker, Uwe

AU - Preijers, Frank

AU - Psarra, Katherina

AU - Richards, Stephen J.

AU - Subira, Dolores

AU - Seymour, John F.

AU - Tindell, Vicky

AU - Vallespi, Teresa

AU - Valent, Peter

AU - van der Velden, Vincent H. J.

AU - Wells, Denise A.

AU - de Witte, Theo M.

AU - Zettl, Florian

AU - Bene, Marie C.

AU - Westers, Theresia M.

PY - 2013/3

Y1 - 2013/3

N2 - An international working group within the European LeukemiaNet gathered, aiming to determine the role of flow cytometry (FC) in myelodysplastic syndromes (MDS). It was agreed that FC has a substantial application in disease characterization, diagnosis and prognosis. FC may also be useful in predicting treatment responses and monitoring novel and standard therapeutic regimens. In this article the rationale is discussed that flow cytometry should be integrated as a part of diagnostic and prognostic scoring systems in MDS.

AB - An international working group within the European LeukemiaNet gathered, aiming to determine the role of flow cytometry (FC) in myelodysplastic syndromes (MDS). It was agreed that FC has a substantial application in disease characterization, diagnosis and prognosis. FC may also be useful in predicting treatment responses and monitoring novel and standard therapeutic regimens. In this article the rationale is discussed that flow cytometry should be integrated as a part of diagnostic and prognostic scoring systems in MDS.

KW - Myelodysplastic syndromes

KW - flow cytometry

KW - ELN

KW - consensus

KW - PROGNOSTIC SCORING SYSTEM

KW - SYNDROMES MDS

KW - BONE-MARROW

KW - T-CELLS

KW - MUTATIONS

KW - DIAGNOSIS

KW - VALIDATION

KW - UTILITY

KW - STANDARDIZATION

KW - IMMUNOPHENOTYPE

U2 - 10.3109/10428194.2012.718341

DO - 10.3109/10428194.2012.718341

M3 - Literature review

SN - 1042-8194

VL - 54

SP - 472

EP - 475

JO - Leukemia and Lymphoma

JF - Leukemia and Lymphoma

IS - 3

ER -

Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group

Abstract

Keywords

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