Single-molecule force spectroscopy predicts a misfolded, domain-swapped conformation in human γD-crystallin protein

Sergi Garcia-Manyes^*, David Giganti, Carmen L. Badilla, Ainhoa Lezamiz, Judit Perales-Calvo, Amy E M Beedle, Julio M. Fernández

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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The nanomechanics of a single protein
Garcia-Manyes, S. (Primary Investigator)
EPSRC Engineering and Physical Sciences Research Council
1/10/2012 → 31/03/2018
Project: Research
The molecular mechanisms determining the onset of protein aggregation revealed by single molecule force-clamp spectroscopy
Garcia-Manyes, S. (Primary Investigator)
BBSRC Biotechnology and Biological Sciences Research Council
1/12/2011 → 1/04/2015
Project: Research
ForcePROT - Conformational dynamics of single molecules under force
Garcia-Manyes, S. (Primary Investigator)
EC European Commission
1/09/2011 → 31/08/2015
Project: Research