TY - JOUR
T1 - Socio-economic status and oesophageal cancer: results from a population-based case-control study in a high-risk area
AU - Islami, Farhad
AU - Kamangar, Farin
AU - Nasrollahzadeh, Dariush
AU - Aghcheli, Karim
AU - Sotoudeh, Masoud
AU - Abedi-Ardekani, Behnoush
AU - Merat, Shahin
AU - Nasseri-Moghaddam, Siavosh
AU - Semnani, Shahryar
AU - Sepehr, Alireza
AU - Wakefield, Jon
AU - Moller, Henrik
AU - Abnet, Christian C.
AU - Dawsey, Sanford M.
AU - Boffetta, Paolo
AU - Malekzadeh, Reza
PY - 2009
Y1 - 2009
N2 - Methods Data were obtained from a population-based case-control study conducted between 2003 and 2007 with 300 histologically proven OSCC cases and 571 matched neighbourhood controls. We used conditional logistic regression to compare cases and controls for individual SES indicators, for a composite wealth score constructed using multiple correspondence analysis, and for factors obtained from factors analysis.
Results We found that various dimensions of SES, such as education, wealth and being married were all inversely related to OSCC. The strongest inverse association was found with education. Compared with no education, the adjusted odds ratios (95% confidence intervals) for primary education and high school or beyond were 0.52 (0.27-0.98) and 0.20 (0.06-0.65), respectively.
Conclusions The strong association of SES with OSCC after adjustment for known risk factors implies the presence of yet unidentified risk factors that are correlated with our SES measures; identification of these factors could be the target of future studies. Our results also emphasize the importance of using multiple SES measures in epidemiological studies.
AB - Methods Data were obtained from a population-based case-control study conducted between 2003 and 2007 with 300 histologically proven OSCC cases and 571 matched neighbourhood controls. We used conditional logistic regression to compare cases and controls for individual SES indicators, for a composite wealth score constructed using multiple correspondence analysis, and for factors obtained from factors analysis.
Results We found that various dimensions of SES, such as education, wealth and being married were all inversely related to OSCC. The strongest inverse association was found with education. Compared with no education, the adjusted odds ratios (95% confidence intervals) for primary education and high school or beyond were 0.52 (0.27-0.98) and 0.20 (0.06-0.65), respectively.
Conclusions The strong association of SES with OSCC after adjustment for known risk factors implies the presence of yet unidentified risk factors that are correlated with our SES measures; identification of these factors could be the target of future studies. Our results also emphasize the importance of using multiple SES measures in epidemiological studies.
U2 - 10.1093/ije/dyp195
DO - 10.1093/ije/dyp195
M3 - Article
VL - 38
SP - 978
EP - 988
JO - International Journal of Epidemiology
JF - International Journal of Epidemiology
IS - 4
ER -
