Sox4you: A New Player in C/EBPα Leukemia

Tsz Kan Fung; Anskar YH Leung; Chi Wai So

doi:10.1016/j.ccr.2013.10.016

Sox4you: A New Player in C/EBPα Leukemia

Tsz Kan Fung, Anskar YH Leung, Chi Wai So

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Although CEBPA mutations are among the most common genetic abnormalities in acute myeloid leukemia (AML), the transformation mechanism remains largely obscure. In this issue of Cancer Cell, Zhang and colleagues report that SOX4 is a direct target and crucial mediator of C/EBPα mutants in AML, revealing a potential therapeutic avenue.

Original language	English
Article number	N/A
Pages (from-to)	557-559
Number of pages	3
Journal	CANCER CELL
Volume	24
Issue number	5
DOIs	https://doi.org/10.1016/j.ccr.2013.10.016
Publication status	Published - Nov 2013

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10.1016/j.ccr.2013.10.016

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title = "Sox4you: A New Player in C/EBPα Leukemia",

abstract = "Although CEBPA mutations are among the most common genetic abnormalities in acute myeloid leukemia (AML), the transformation mechanism remains largely obscure. In this issue of Cancer Cell, Zhang and colleagues report that SOX4 is a direct target and crucial mediator of C/EBPα mutants in AML, revealing a potential therapeutic avenue.",

author = "Fung, {Tsz Kan} and Leung, {Anskar YH} and So, {Chi Wai}",

year = "2013",

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AU - Fung, Tsz Kan

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AU - So, Chi Wai

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N2 - Although CEBPA mutations are among the most common genetic abnormalities in acute myeloid leukemia (AML), the transformation mechanism remains largely obscure. In this issue of Cancer Cell, Zhang and colleagues report that SOX4 is a direct target and crucial mediator of C/EBPα mutants in AML, revealing a potential therapeutic avenue.

AB - Although CEBPA mutations are among the most common genetic abnormalities in acute myeloid leukemia (AML), the transformation mechanism remains largely obscure. In this issue of Cancer Cell, Zhang and colleagues report that SOX4 is a direct target and crucial mediator of C/EBPα mutants in AML, revealing a potential therapeutic avenue.

U2 - 10.1016/j.ccr.2013.10.016

DO - 10.1016/j.ccr.2013.10.016

M3 - Article

SN - 1535-6108

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EP - 559

JO - CANCER CELL

JF - CANCER CELL

IS - 5

M1 - N/A

ER -

Sox4you: A New Player in C/EBPα Leukemia

Abstract

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