STACOM challenge: Simulating left ventricular mechanics in the canine heart

Liia Asner*, Myria Hadjicharalambous, Jack Lee, David Nordsletten

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

7 Citations (Scopus)

Abstract

In this paper we outline our approach for creating subjectspecific whole-cycle canine left-ventricular models, as part of the 2014 STACOM Challenge. Each canine heart was modeled using the principle of stationary potential energy, with the myocardium treated as a nearly incompressible hyperelastic material. Given incomplete data on the motion and behavior of each canine heart, we decreased model complexity by employing reduced–parameter constitutive laws. Additionally, base plane motion and left ventricular volume input data were integrated into the cardiac cycle model through the inclusion of novel external energy potentials (using Lagrange multipliers), which allow for relaxed adherence to the constraints and minimize spurious energy modes stemming from model simplification and data noise. Subsequently, using the available data we employ the reduced-order unscented Kalman filter (ROUKF) approach to estimate the myocardial passive parameters and active tension. Finally, along with model predictions for each canine, we assess the spatial convergence and robustness of our model.

Original languageEnglish
Title of host publicationStatistical Atlases and Computational Models of the Heart - Imaging and Modelling Challenges
Subtitle of host publication5th International Workshop, STACOM 2014, Held in Conjunction with MICCAI 2014, Boston, MA, USA, September 18, 2014, Revised Selected Papers
PublisherSpringer-Verlag Berlin Heidelberg
Pages123-134
Number of pages12
ISBN (Electronic)9783319146782
ISBN (Print)9783319146775
DOIs
Publication statusPublished - 2015
Event5th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2014 Held in Conjunction with Medical Image Computing and Computer Assisted Intervention Conference, MICCAI 2014 - Boston, United States
Duration: 18 Sept 201418 Sept 2014

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume8896
ISSN (Print)03029743
ISSN (Electronic)16113349

Conference

Conference5th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2014 Held in Conjunction with Medical Image Computing and Computer Assisted Intervention Conference, MICCAI 2014
Country/TerritoryUnited States
CityBoston
Period18/09/201418/09/2014

Keywords

  • Canine heart
  • Cardiac mechanics
  • Data assimilation
  • Parameter estimation

Fingerprint

Dive into the research topics of 'STACOM challenge: Simulating left ventricular mechanics in the canine heart'. Together they form a unique fingerprint.

Cite this