Stereotactic Body Radiotherapy: A Review

A. Martin; A. Gaya

doi:10.1016/j.clon.2009.12.003

Stereotactic Body Radiotherapy: A Review

A. Martin^*, A. Gaya

^*Corresponding author for this work

Harley St Clin, CyberKnife Ctr

Research output: Contribution to journal › Literature review › peer-review

138 Citations (Scopus)

Abstract

Stereotactic body radiotherapy (SBRT) combines the challenge of meeting the stringent dosimetric requirements of stereotactic radiosurgery with that of accounting for the physiological movement of tumour and normal tissue. Here we present an overview of the history and development of SORT and discuss the radiobiological rationale upon which it is based. The published results of SORT for lung, liver, pancreas, kidney, prostate and spinal lesions are reviewed and summarised. The current evidence base is appraised and important ongoing trials are identified.

Original language	English
Pages (from-to)	157-172
Number of pages	16
Journal	Clinical Oncology
Volume	22
Issue number	3
DOIs	https://doi.org/10.1016/j.clon.2009.12.003
Publication status	Published - Apr 2010

Keywords

Cyberknife
radiosurgery
stereotactic body radiation therapy
stereotactic body radiotherapy
CELL LUNG-CANCER
PRIMARY HEPATOCELLULAR-CARCINOMA
ADVANCED PANCREATIC-CARCINOMA
DOSE CONFORMAL RADIOTHERAPY
SPINAL-CORD COMPRESSION
RADIATION-THERAPY SBRT
LOCAL TUMOR-CONTROL
PHASE I/II TRIAL
STAGE-I
PROSTATE-CANCER

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.clon.2009.12.003

Cite this

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title = "Stereotactic Body Radiotherapy: A Review",

abstract = "Stereotactic body radiotherapy (SBRT) combines the challenge of meeting the stringent dosimetric requirements of stereotactic radiosurgery with that of accounting for the physiological movement of tumour and normal tissue. Here we present an overview of the history and development of SORT and discuss the radiobiological rationale upon which it is based. The published results of SORT for lung, liver, pancreas, kidney, prostate and spinal lesions are reviewed and summarised. The current evidence base is appraised and important ongoing trials are identified.",

keywords = "Cyberknife, radiosurgery, stereotactic body radiation therapy, stereotactic body radiotherapy, CELL LUNG-CANCER, PRIMARY HEPATOCELLULAR-CARCINOMA, ADVANCED PANCREATIC-CARCINOMA, DOSE CONFORMAL RADIOTHERAPY, SPINAL-CORD COMPRESSION, RADIATION-THERAPY SBRT, LOCAL TUMOR-CONTROL, PHASE I/II TRIAL, STAGE-I, PROSTATE-CANCER",

author = "A. Martin and A. Gaya",

year = "2010",

month = apr,

doi = "10.1016/j.clon.2009.12.003",

language = "English",

volume = "22",

pages = "157--172",

journal = "Clinical Oncology",

issn = "0936-6555",

publisher = "W.B. Saunders Ltd",

number = "3",

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TY - JOUR

T1 - Stereotactic Body Radiotherapy: A Review

AU - Martin, A.

AU - Gaya, A.

PY - 2010/4

Y1 - 2010/4

N2 - Stereotactic body radiotherapy (SBRT) combines the challenge of meeting the stringent dosimetric requirements of stereotactic radiosurgery with that of accounting for the physiological movement of tumour and normal tissue. Here we present an overview of the history and development of SORT and discuss the radiobiological rationale upon which it is based. The published results of SORT for lung, liver, pancreas, kidney, prostate and spinal lesions are reviewed and summarised. The current evidence base is appraised and important ongoing trials are identified.

AB - Stereotactic body radiotherapy (SBRT) combines the challenge of meeting the stringent dosimetric requirements of stereotactic radiosurgery with that of accounting for the physiological movement of tumour and normal tissue. Here we present an overview of the history and development of SORT and discuss the radiobiological rationale upon which it is based. The published results of SORT for lung, liver, pancreas, kidney, prostate and spinal lesions are reviewed and summarised. The current evidence base is appraised and important ongoing trials are identified.

KW - Cyberknife

KW - radiosurgery

KW - stereotactic body radiation therapy

KW - stereotactic body radiotherapy

KW - CELL LUNG-CANCER

KW - PRIMARY HEPATOCELLULAR-CARCINOMA

KW - ADVANCED PANCREATIC-CARCINOMA

KW - DOSE CONFORMAL RADIOTHERAPY

KW - SPINAL-CORD COMPRESSION

KW - RADIATION-THERAPY SBRT

KW - LOCAL TUMOR-CONTROL

KW - PHASE I/II TRIAL

KW - STAGE-I

KW - PROSTATE-CANCER

U2 - 10.1016/j.clon.2009.12.003

DO - 10.1016/j.clon.2009.12.003

M3 - Literature review

SN - 0936-6555

VL - 22

SP - 157

EP - 172

JO - Clinical Oncology

JF - Clinical Oncology

IS - 3

ER -

Stereotactic Body Radiotherapy: A Review

Abstract

Keywords

UN SDGs

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