Structure and catalytic activity of some soluble polyethylene glycol-peptide conjugates

D R Kelly, T T T Bui, E Caroff, A F Drake, S M Roberts

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Soluble catalysts for the Julia-Colonna asymmetric epoxidation reaction have been constructed in three different ways, using NH2-PEG-OMe as the support system: suitable solvents have been identified and it is shown that the degree of helicity of the conjugates correlates with the extent of conversion and (to a lesser extent) the enantioselectivity of epoxidation. (C) 2004 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)3885 - 3888
Number of pages4
JournalTETRAHEDRON LETTERS
Volume45
Issue number20
DOIs
Publication statusPublished - 10 May 2004

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