Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity

Lauren M. Gittings; Steven Boeynaems; Daniel Lightwood; Alison Clargo; Sarfaraj Topia; Lisa Nakayama; Claire Troakes; David M.A. Mann; Aaron D. Gitler; Tammaryn Lashley; Adrian M. Isaacs

doi:10.1007/s00401-019-02104-x

Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity

Lauren M. Gittings, Steven Boeynaems, Daniel Lightwood, Alison Clargo, Sarfaraj Topia, Lisa Nakayama, Claire Troakes, David M.A. Mann, Aaron D. Gitler, Tammaryn Lashley, Adrian M. Isaacs^*

^*Corresponding author for this work

Basic and Clinical Neuroscience

Research output: Contribution to journal › Letter › peer-review

31 Citations (Scopus)

Original language	English
Pages (from-to)	407-410
Number of pages	4
Journal	Acta Neuropathologica
Volume	139
Issue number	2
DOIs	https://doi.org/10.1007/s00401-019-02104-x
Publication status	Published - 1 Feb 2020

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Gittings, L. M., Boeynaems, S., Lightwood, D., Clargo, A., Topia, S., Nakayama, L., Troakes, C., Mann, D. M. A., Gitler, A. D., Lashley, T., & Isaacs, A. M. (2020). Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. Acta Neuropathologica, 139(2), 407-410. https://doi.org/10.1007/s00401-019-02104-x

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title = "Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity",

author = "Gittings, {Lauren M.} and Steven Boeynaems and Daniel Lightwood and Alison Clargo and Sarfaraj Topia and Lisa Nakayama and Claire Troakes and Mann, {David M.A.} and Gitler, {Aaron D.} and Tammaryn Lashley and Isaacs, {Adrian M.}",

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doi = "10.1007/s00401-019-02104-x",

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Gittings, LM, Boeynaems, S, Lightwood, D, Clargo, A, Topia, S, Nakayama, L, Troakes, C, Mann, DMA, Gitler, AD, Lashley, T & Isaacs, AM 2020, 'Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity', Acta Neuropathologica, vol. 139, no. 2, pp. 407-410. https://doi.org/10.1007/s00401-019-02104-x

TY - JOUR

T1 - Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity

AU - Gittings, Lauren M.

AU - Boeynaems, Steven

AU - Lightwood, Daniel

AU - Clargo, Alison

AU - Topia, Sarfaraj

AU - Nakayama, Lisa

AU - Troakes, Claire

AU - Mann, David M.A.

AU - Gitler, Aaron D.

AU - Lashley, Tammaryn

AU - Isaacs, Adrian M.

PY - 2020/2/1

Y1 - 2020/2/1

UR - http://www.scopus.com/inward/record.url?scp=85076834689&partnerID=8YFLogxK

U2 - 10.1007/s00401-019-02104-x

DO - 10.1007/s00401-019-02104-x

M3 - Letter

C2 - 31832771

AN - SCOPUS:85076834689

SN - 0001-6322

VL - 139

SP - 407

EP - 410

JO - Acta Neuropathologica

JF - Acta Neuropathologica

IS - 2

ER -

Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity

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