TY - JOUR
T1 - The future of food allergy
T2 - Challenging existing paradigms of clinical practice
AU - Anagnostou, Aikaterini
AU - Lieberman, Jay
AU - Greenhawt, Matthew
AU - Mack, Douglas Paul
AU - Santos, Alexandra F.
AU - Venter, Carina
AU - Stukus, David
AU - Turner, Paul J.
AU - Brough, Helen A.
N1 - Funding Information:
Aikaterini Anagnostou reports institutional funding from Aimmune Therapeutics, Novartis and FARE (Food Allergy Research and Education) and personal fees (consultation and speaker services) from DBV Technologies, ALK and FARE. Jay Lieberman reports Institutional research support from Regeneron, DBV technologies, Aimmune and Advisory Board Member (honorarium) for DBV technologies. Matthew Greenhawt is a consultant for Aquestive; is a member of physician/medical advisory boards for DBV Technologies, Sanofi/Regeneron, Nutricia, Novartis, Acquestive, Allergy Therapeutics, AstraZeneca, ALK‐Abello and Prota; is an unpaid member of the scientific advisory council for the National Peanut Board and medical advisory board of the International Food Protein Induced Enterocolitis Syndrome Association; is a member of the Brighton Collaboration Criteria Vaccine Anaphylaxis 2.0 working group; is the senior associate editor for the Annals of Allergy, Asthma and Immunology and is member of the Joint Taskforce on Allergy Practice Parameters. He has received honorarium for lectures from ImSci, MedLearningGroup, RMEI Medical Education and multiple state/local allergy societies. He received past research support ending in 2020 from the Agency for Healthcare Quality and Research (K08‐HS024599). Douglas Paul Mack has provided consultation and speaker services for Aimmune, Bausch Health, ALK‐Abello, Medexus and Miravo and is an investigator for DBV and ALK‐Abello and serves on the editorial board of the Journal of Food Allergy. Alexandra F. Santos reports grants from the Medical Research Council, Food Allergy Research and Education, BBSRC, Rosetrees Trust, Asthma UK, Immune Tolerance Network/National Institute of Allergy and Infectious Diseases (NIAID, NIH); speaker fees for Thermo Scientific, Nestle, Novartis, Buhlmann; consultancy fees for Allergy Therapeutics, IgGenix, Novartis and Stallergenes, as well as research support from Buhlmann and Thermo Fisher Scientific through a collaboration agreement with King's College London, outside the submitted work. Carina Venter reports grants from Reckitt Benckiser; personal fees from Reckitt Benckiser, Nestle Nutrition Institute, Danone, Abbott Nutrition Else Nutrition, Sifter, Owyn and Before Brands, outside the submitted work. David Stukus reports Consultant: ARS Pharmaceuticals, Before Brands, Novartis, ParentMD; Research support: DBV Technologies; Social media editor for the American Academy of Allergy, Asthma and Immunology; Member, Board of Regents for the American College of Allergy, Asthma and Immunology; Member, Joint Task Force on Practice Parameters for Allergy/Immunology; Associated Editor, Annals of Allergy, Asthma and Immunology P.J. Turner reports grants from UK Medical Research Council, NIHR/Imperial BRC and JM Charitable Foundation; personal fees from UK Food Standards Agency, Aimmune Therapeutics, Allergenis, Aquestive Therapeutics and Novartis. Helen A Brough reports speaker fees from DBV Technologies, GSK and Sanofi, outside of the submitted work.
Publisher Copyright:
© 2023 European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.
PY - 2023/7
Y1 - 2023/7
N2 - The field of food allergy has seen tremendous change over the past 5–10 years with seminal studies redefining our approach to prevention and management and novel testing modalities in the horizon. Early introduction of allergenic foods is now recommended, challenging the previous paradigm of restrictive avoidance. The management of food allergy has shifted from a passive avoidance approach to active interventions that aim to provide protection from accidental exposures, decrease allergic reaction severity and improve the quality of life of food-allergic patients and their families. Additionally, novel diagnostic tools are making their way into clinical practice with the goal to reduce the need for food challenges and assist physicians in the—often complex—diagnostic process. With all the new developments and available choices for diagnosis, prevention and therapy, shared decision-making has become a key part of medical consultation, enabling patients to make the right choice for them, based on their values and preferences. Communication with patients has also become more complex over time, as patients are seeking advice online and through social media, but the information found online may be outdated, incorrect, or lacking in context. The role of the allergist has evolved to embrace all the above exciting developments and provide patients with the optimal care that fits their needs. In this review, we discuss recent developments as well as the evolution of the field of food allergy in the next decade.
AB - The field of food allergy has seen tremendous change over the past 5–10 years with seminal studies redefining our approach to prevention and management and novel testing modalities in the horizon. Early introduction of allergenic foods is now recommended, challenging the previous paradigm of restrictive avoidance. The management of food allergy has shifted from a passive avoidance approach to active interventions that aim to provide protection from accidental exposures, decrease allergic reaction severity and improve the quality of life of food-allergic patients and their families. Additionally, novel diagnostic tools are making their way into clinical practice with the goal to reduce the need for food challenges and assist physicians in the—often complex—diagnostic process. With all the new developments and available choices for diagnosis, prevention and therapy, shared decision-making has become a key part of medical consultation, enabling patients to make the right choice for them, based on their values and preferences. Communication with patients has also become more complex over time, as patients are seeking advice online and through social media, but the information found online may be outdated, incorrect, or lacking in context. The role of the allergist has evolved to embrace all the above exciting developments and provide patients with the optimal care that fits their needs. In this review, we discuss recent developments as well as the evolution of the field of food allergy in the next decade.
KW - food allergy
KW - novel diagnostics
KW - prevention
KW - shared decision-making
KW - therapy
UR - http://www.scopus.com/inward/record.url?scp=85159083862&partnerID=8YFLogxK
U2 - 10.1111/all.15757
DO - 10.1111/all.15757
M3 - Review article
C2 - 37129472
AN - SCOPUS:85159083862
SN - 0105-4538
VL - 78
SP - 1847
EP - 1865
JO - Allergy: European Journal of Allergy and Clinical Immunology
JF - Allergy: European Journal of Allergy and Clinical Immunology
IS - 7
ER -