The possible clinical predictors of fatigue in Parkinson's disease: a study of 135 patients as part of international nonmotor scale validation project

Vinod Metta; Kartik Logishetty; P Martinez-Martin; Heather M Gage; P E S Schartau; T K Kaluarachchi; Anne-Marie Martin; Per Odin; P Barone; Fabrizio Stocchi; A Antonini; K Ray Chaudhuri

doi:10.4061/2011/125271

The possible clinical predictors of fatigue in Parkinson's disease: a study of 135 patients as part of international nonmotor scale validation project

Vinod Metta, Kartik Logishetty, P Martinez-Martin, Heather M Gage, P E S Schartau, T K Kaluarachchi, Anne-Marie Martin, Per Odin, P Barone, Fabrizio Stocchi, A Antonini, K Ray Chaudhuri^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.

Original language	English
Article number	125271
Number of pages	7
Journal	Parkinson's disease
Volume	2011
DOIs	https://doi.org/10.4061/2011/125271
Publication status	Published - 2011

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Metta, V., Logishetty, K., Martinez-Martin, P., Gage, H. M., Schartau, P. E. S., Kaluarachchi, T. K., Martin, A.-M., Odin, P., Barone, P., Stocchi, F., Antonini, A., & Chaudhuri, K. R. (2011). The possible clinical predictors of fatigue in Parkinson's disease: a study of 135 patients as part of international nonmotor scale validation project. Parkinson's disease, 2011, Article 125271. https://doi.org/10.4061/2011/125271

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abstract = "Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.",

author = "Vinod Metta and Kartik Logishetty and P Martinez-Martin and Gage, {Heather M} and Schartau, {P E S} and Kaluarachchi, {T K} and Anne-Marie Martin and Per Odin and P Barone and Fabrizio Stocchi and A Antonini and Chaudhuri, {K Ray}",

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Metta, V, Logishetty, K, Martinez-Martin, P, Gage, HM, Schartau, PES, Kaluarachchi, TK, Martin, A-M, Odin, P, Barone, P, Stocchi, F, Antonini, A & Chaudhuri, KR 2011, 'The possible clinical predictors of fatigue in Parkinson's disease: a study of 135 patients as part of international nonmotor scale validation project', Parkinson's disease, vol. 2011, 125271. https://doi.org/10.4061/2011/125271

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AU - Metta, Vinod

AU - Logishetty, Kartik

AU - Martinez-Martin, P

AU - Gage, Heather M

AU - Schartau, P E S

AU - Kaluarachchi, T K

AU - Martin, Anne-Marie

AU - Odin, Per

AU - Barone, P

AU - Stocchi, Fabrizio

AU - Antonini, A

AU - Chaudhuri, K Ray

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AB - Fatigue is a common yet poorly understood and underresearched nonmotor symptom in Parkinson's disease. Although fatigue is recognized to significantly affect health-related quality of life, it remains underrecognised and empirically treated. In this paper, the prevalence of fatigue as measured by a validated visual analogue scale and the Parkinson's disease nonmotor symptoms scale (PDNMSS) was correlated with other motor and nonmotor comorbidities. In a cohort of patients from a range of disease stages, occurrence of fatigue correlated closely with more advanced Parkinson's disease, as well as with depression, anxiety, and sleep disorders, hinting at a common underlying basis.

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JO - Parkinson's disease

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M1 - 125271

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The possible clinical predictors of fatigue in Parkinson's disease: a study of 135 patients as part of international nonmotor scale validation project

Abstract

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