Abstract
Background and Aims: We extend our recent findings on trajectories
of depression symptoms after stroke, and investigates these in men and
women separately.
Method: Data from the South London Stroke Register (1998-2013),
including 1098 patients (56% Males) who responded to the Hospital
Anxiety and Depression scale (HADs), at least 3 times and survived at
least 5 years, were used. Trajectories of depression were detected using
group based trajectory modelling (GBTM).
Results: Three trajectories were identified for males: 47.3% have mild
symptoms that may worsen over time, mean depression score, 1.8
(se ¼ 0.24); 43.3% have mild/moderate symptoms that could increase
over time, mean 5.9 (se ¼ 0.33), and 9.4% had severe symptoms that
persist over 5 years, mean 11.8 (se ¼ 0.39), higher than 8 (recognised
64 European Stroke Journal 2(1S)
cut-off for depression casseness). For women, 4 groups were identified (IIV)
with stable but higher levels of symptoms. Predicted mean scores
were, 2.4 (se ¼ 0.23), 5.9 (se ¼ 0.30), 9.7 (se ¼ 0.39) and 14.4
(se ¼ 0.47), and the groups comprised 4.6%, 18%, 46% and 31.4% respectively.
Predicted means were consistent with observed means (Figure 1).
Sensitivity analyse based on different inclusion criteria supported the 5
years’ results.
Conclusion: Women are at higher risk of depression, with 22.6% scoring
above 8, compared to 9.4% of men. The study provides better insight
into the natural history of depression that may help the provision of
appropriate and timely health care.
Figure 1.
of depression symptoms after stroke, and investigates these in men and
women separately.
Method: Data from the South London Stroke Register (1998-2013),
including 1098 patients (56% Males) who responded to the Hospital
Anxiety and Depression scale (HADs), at least 3 times and survived at
least 5 years, were used. Trajectories of depression were detected using
group based trajectory modelling (GBTM).
Results: Three trajectories were identified for males: 47.3% have mild
symptoms that may worsen over time, mean depression score, 1.8
(se ¼ 0.24); 43.3% have mild/moderate symptoms that could increase
over time, mean 5.9 (se ¼ 0.33), and 9.4% had severe symptoms that
persist over 5 years, mean 11.8 (se ¼ 0.39), higher than 8 (recognised
64 European Stroke Journal 2(1S)
cut-off for depression casseness). For women, 4 groups were identified (IIV)
with stable but higher levels of symptoms. Predicted mean scores
were, 2.4 (se ¼ 0.23), 5.9 (se ¼ 0.30), 9.7 (se ¼ 0.39) and 14.4
(se ¼ 0.47), and the groups comprised 4.6%, 18%, 46% and 31.4% respectively.
Predicted means were consistent with observed means (Figure 1).
Sensitivity analyse based on different inclusion criteria supported the 5
years’ results.
Conclusion: Women are at higher risk of depression, with 22.6% scoring
above 8, compared to 9.4% of men. The study provides better insight
into the natural history of depression that may help the provision of
appropriate and timely health care.
Figure 1.
| Original language | English |
|---|---|
| Title of host publication | European journal of Stroke |
| Volume | Vol 2 |
| Edition | 1_suppl, 2017 |
| Publication status | Published - May 2017 |