Ultrabubble: A Laminated Ultrasound Contrast Agent with Narrow Size Range

Pei-Lun Lin; Robert Eckersley; Elizabeth A. H. Hall

doi:10.1002/adma.200901096

Ultrabubble: A Laminated Ultrasound Contrast Agent with Narrow Size Range

Pei-Lun Lin, Robert Eckersley, Elizabeth A. H. Hall

Biomedical Engineering Department

University of Cambridge

Research output: Contribution to journal › Article › peer-review

76 Citations (Scopus)

Abstract

A laminated shell microcapsule is described resisting aggregation and withstanding ultrasound destruction, showing a good backscatter signal, as shown in the figure. Templated synthesis produces versatile monodisperse capsules <3 mu m, with ultrasound-pressure dependency allowing rupture above MI similar to 1.5 (at 2 MHz), suitable for future development as both controlled-delivery agent and contrast agent.

Original language	English
Pages (from-to)	3949-52
Number of pages	4
Journal	ADVANCED MATERIALS
Volume	21
Issue number	38-39
DOIs	https://doi.org/10.1002/adma.200901096
Publication status	Published - 19 Oct 2009

Access to Document

10.1002/adma.200901096

Cite this

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title = "Ultrabubble: A Laminated Ultrasound Contrast Agent with Narrow Size Range",

abstract = "A laminated shell microcapsule is described resisting aggregation and withstanding ultrasound destruction, showing a good backscatter signal, as shown in the figure. Templated synthesis produces versatile monodisperse capsules <3 mu m, with ultrasound-pressure dependency allowing rupture above MI similar to 1.5 (at 2 MHz), suitable for future development as both controlled-delivery agent and contrast agent.",

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