TY - JOUR
T1 - Understanding psychosis complexity through a syndemic framework: A systematic review
AU - Zahid, Uzma
AU - Lawrence, Erin grace
AU - De freitas, Daniela fonseca
AU - Parri, Lois a.
AU - Quadros, Wesley
AU - Hua, Phuong
AU - Harriss, Eli
AU - Oliver, Dominic
AU - Hosang, Georgina m.
AU - Bhui, Kamaldeep
N1 - Funding Information:
DFF work was supported by the Lankelly Chase Foundation , which funded the emerging work of the Synergi Collaborative Centre (a 5-year national initiative to build a knowledge hub on ethnic inequalities and multiple disadvantages in severe mental illness in the UK). DFF received funding from the NIHR Maudsley Biomedical Research Centre , as such, this study represents independent research partly funded by the NIHR Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King’s College London .
Funding Information:
DFF work was supported by the Lankelly Chase Foundation, which funded the emerging work of the Synergi Collaborative Centre (a 5-year national initiative to build a knowledge hub on ethnic inequalities and multiple disadvantages in severe mental illness in the UK). DFF received funding from the NIHR Maudsley Biomedical Research Centre, as such, this study represents independent research partly funded by the NIHR Maudsley Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London.
Publisher Copyright:
© 2024 The Authors
PY - 2024/4/1
Y1 - 2024/4/1
N2 - Psychotic conditions pose significant challenges due to their complex aetiology and impact on individuals and communities. Syndemic theory offers a promising framework to understand the interconnectedness of various health and social problems in the context of psychosis. This systematic review aims to examine existing literature on testing whether psychosis is better understood as a component of a syndemic. We conducted a systematic search of 7 databases, resulting in the inclusion of five original articles. Findings from these studies indicate a syndemic characterized by the coexistence of various health and social conditions, are associated with a greater risk of psychosis, adverse health outcomes, and disparities, especially among ethnic minorities and deprived populations. This review underscores the compelling need for a new paradigm and datasets that can investigate how psychosis emerges in the context of a syndemic, ultimately guiding more effective preventive and care interventions as well as policies to improve the health of marginalised communities living in precarity.
AB - Psychotic conditions pose significant challenges due to their complex aetiology and impact on individuals and communities. Syndemic theory offers a promising framework to understand the interconnectedness of various health and social problems in the context of psychosis. This systematic review aims to examine existing literature on testing whether psychosis is better understood as a component of a syndemic. We conducted a systematic search of 7 databases, resulting in the inclusion of five original articles. Findings from these studies indicate a syndemic characterized by the coexistence of various health and social conditions, are associated with a greater risk of psychosis, adverse health outcomes, and disparities, especially among ethnic minorities and deprived populations. This review underscores the compelling need for a new paradigm and datasets that can investigate how psychosis emerges in the context of a syndemic, ultimately guiding more effective preventive and care interventions as well as policies to improve the health of marginalised communities living in precarity.
UR - http://www.scopus.com/inward/record.url?scp=85187225320&partnerID=8YFLogxK
U2 - 10.1016/j.neubiorev.2024.105614
DO - 10.1016/j.neubiorev.2024.105614
M3 - Article
SN - 0149-7634
VL - 159
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
M1 - 105614
ER -