Updates on Genome-Wide Association Findings in Eating Disorders and Future Application to Precision Medicine

Lauren Breithaupt, Christopher Hubel, Cynthia M Bulik

Research output: Contribution to journalReview articlepeer-review

22 Citations (Scopus)
136 Downloads (Pure)

Abstract

Heterogeneity, frequent diagnostic fluctuation across presentations, and global concerns with the absence of effective treatments all encourage science that moves the field toward individualized or precision medicine in eating disorders. We review recent advances in psychiatric genetics focusing on genome-wide association studies (GWAS) in eating disorders. Given that the only eating disorder to be the subject of GWAS to date is anorexia nervosa, we review anorexia GWAS and enumerate the prospects and challenges of a genomics-driven approach towards personalized intervention in eating disorders.

Original languageEnglish
Pages (from-to)1102-1110
Number of pages9
JournalCurrent Neuropharmacology
Volume16
Issue number8
DOIs
Publication statusPublished - 2018

Keywords

  • Feeding and Eating Disorders/genetics
  • Genetic Predisposition to Disease
  • Humans
  • Precision Medicine

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