Infectious Diseases

Nicole Acuti
- Infectious Diseases
Person: Doctor of Philosophy
Monica Agromayor
- Infectious Diseases - Reader in Organelle Cell Biology
Person: Academic
Nathalia Almeida Dos Santos
- Infectious Diseases - Post Doctoral Research Associate
Person: Research

Accelarated immune ageing is associated with COVID-19 disease severity
on behalf of the PHOSP-COVID Study collaborative group, ISARIC4C Investigators, Abel, K., Ahmad, S., Ahmed, R., Ali, M., Allen, R. J., Almeida, P., Anderson, D., Armstrong, L., Armstrong, N., Ashworth, M., Ayoub, A., Baggott, R., Bailey, L., Baldwin, D., Ballard, C., Banerjee, A., Bates, A. & Begum, M. & 279 others, Bell, D., Bell, R., Berry, C., Bhui, K., Bramham, K., Breen, G., Brookes, C., Broome, M., Brown, A., Brown, A., Brown, J., Brown, J., Brown, J., Brown, M., Brown, M., Burns, A., Butt, A., Byrne, S., Carson, G., Carter, P., Chalder, T., CHambers, R. C., Chan, F., Chen, J., Cheng, Y., Chiribiri, A., Choudhury, N., Chowienczyk, P., Clark, D., Clark, C., Clarke, J., Cole, J., Coleman, C., Connolly, B., Connor, L., Cook, A., Cooper, B., Cooper, J., Cooper, S., Craig, T., Cross, A., David, A., Davies, E., Davies, G., Davies, G., Davies, K., Davies, M. J., Dawson, J., Donaldson, A., Dong, T., Dougherty, A., Dowling, R., Dunn, S., Edwards, S., Elliott, A., Elliott, K., Evans, D., Evans, H., Evans, J., Evans, R. I., Evans, R. I., Evans, T., Finch, J., Fisher, H., Flynn, M., Ford, A., Francis, R., Fu, X., Gill, M., Goodwin, C., Gooptu, B., Gregory, H., Gregory, R., Grieve, D., Griffiths, L., Gupta, A., Hall, L., Harris, E., Harris, V. C., Harrison, P., Hart, N., Harvey, A., Harvey, M., Hayday, A., Henderson, M., Ho, L. P., Holden, S., Holland, M., Holmes, M., Hosseini, A., Hotopf, M., Howard, L. S., Hughes, A. D., Hughes, J., Hughes, R., Husain, M., Ismail, K., Jackson, T., Jacob, J., James, W. Y., Jenkins, R. G., Johnson, C., Johnson, S., Jolley, C. J., Jones, D., Jones, G., Jones, H., Jones, H., Jones, I., Jones, L., Jones, M. G., Jones, S., Jose, S., Kaltsakas, G., Kelly, S., Kerr, S., Khan, F., King, B., Knight, S., Kon, S. S., Kon, S. S., Laing, C., Lasserson, D., Lawson, C., Lawson, C., Lee, D., Lee, J. H., Lewis, D., Lewis, J., Li, X., Lim, L., Lloyd, A., Major, E., Malim, M., Man, W. D. C., Mandal, S., Mangion, K., Marsh, S., Marshall, B., Marshall, M., Martin, J., Martinez, L. M., McMahon, M. J., Mehta, P., Miller, C., Mills, C., Mitchell, J., Mohamed, A., Mohammed, S., Morley, A., Morrow, A., Moss, A. J., Neal, A., Newby, D. E., Newman, J., Nicholson, T., Ostermann, M., Owen, J., Pariante, C., Parker, S., Patel, B., Patel, M., Patel, S., Payne, S., Pearce, L., Peng, Y., Pennington, C., Pfeffer, P., Plant, H., Plein, S., Porter, J. C., Porter, J., Powell, N., Pratt, J., Price, A., Price, C., Price, C., Price, D., Prickett, A., Quigley, J., Qureshi, I. N., Rahman, N. M., Reddy, A., Rees, M., Rees, T., Reynolds, W., Richards, A., Richardson, E., Richardson, M., Roberts, K., Robertson, E., Robinson, E., Robinson, L., Rodger, J., Ross, A., Rowe, A., Rowland, A., Rowland, J., Russell, R., Sage, E. K., Saunders, K., Saunders, R. M., Saunders, P., Scott, J. T., Shah, A., Shah, K., Shah, P., Shankar-Hari, M., Sharma, M., Sharpe, C., Shaw, A., Shaw, K., Simpson, J., Singh, C., Singh, S., Singh, S., Smith, A., Smith, D., Smith, S., Smith, J., Smith, L., Spencer, L. G., Stephenson, L., Stewart, I., Stockdale, S., Stone, R., Tan, A. L., Taylor, A., Taylor, C., Taylor, J., Terry, S., Thomas, C., Thomas, D. C., Thomas, S., Thomas, A. K., Thompson, T., Thompson, A. A. R., Tilley, J., Tomlinson, J., Turner, S., Turner, K., Wade, P., Wainwright, T., Walker, S., Walker, S., Walsh, J. A., Walsh, S., Ward, T. J. C., Watson, E., Watson, L., Watson, J., Weir McCall, J., Welch, C., Wessely, S., West, S., White, S., Whitney, J., Whittaker, S., Wild, J., Williams, B., Williams, N., Williams, N., Williams, J., Willoughby, J., Wilson, A., Wilson, D., Wilson, I., Wood, C., Woods, J., Wright, C., Wright, L., Wright, S., Xu, M., Yip, K. P., Young, B., Young, S., Young, A., Zhao, B. & Zheng, B., 11 Jan 2024, (E-pub ahead of print) In: Immunity and Ageing. 21, 1, 6.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Citations (Scopus)
A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease
Avanzato, V. A., Bushmaker, T., Oguntuyo, K. Y., Yinda, C. K., Duyvesteyn, H. M. E., Stass, R., Meade-White, K., Rosenke, R., Thomas, T., van Doremalen, N., Saturday, G., Doores, K. J., Lee, B., Bowden, T. A. & Munster, V. J., Oct 2024, In: Journal of Virology. 98, 10, e00638-24.
Research output: Contribution to journal › Article › peer-review

Open Access
Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages
Pickering, S., Wilson, H., Bravo, E., Perera, M., Seow, J., Graham, C., Almeida Dos Santos, N., Fotopoulos, L., Williams, T., Moitra, A., Winstone, H., Nissen, T. A., Ribeiro Galao, R. P., Snell, L. B., Doores, K., Malim, M. & Neil, S., 7 Nov 2024, (Accepted/In press) In: Nature Communications.
Research output: Contribution to journal › Article › peer-review

1 Not started
22 Active
227 Finished

Translating science into the clinic - new approaches and tools for predicting risk of preterm birth
Tribe, R. (Primary Investigator), Martinez Nunez, R. (Co-Investigator) & Vigilante, A. (Co-Investigator)
Rosetrees Trust
1/10/2024 → 30/09/2027
Project: Research
Generation of human CAR-T cells with tissue-resident memory features for improved treatment of hepatocellular carcinoma
Schurich, A. (Primary Investigator)
CRUK Cancer Research UK
23/09/2024 → 22/09/2028
Project: Research
Improving therapeutic success by directing CAR-T cell metabolism through co-stimulation
Schurich, A. (Primary Investigator) & Sompairac, N. (Co-Investigator)
MRC Medical Research Council
1/09/2024 → 31/08/2027
Project: Research

Cell Reports Medicine (Journal)
Maher, J. (Editor), Halim, L. (Editor), Whilding, L. (Editor), Muliaditan, T. (Editor), Draper, B. (Editor), Achkova, D. (Editor), Kauser, F. (Editor), Glover, M. (Editor), Bechman, N. (Editor), Arulappu, A. (Editor), Sanchez, J. (Editor), Flaherty, K. R. (Editor), Obajdin, J. (Editor), Grigoriadis, K. (Editor), Antoine, P. (Editor), Larcombe-Young, D. (Editor), Hull, C. (Editor), Buus, R. (Editor), Gordon, P. (Editor), Grigoriadis, A. (Editor), davies, D. M. (Editor) & Schurich, A. (Editor)
5 Nov 2021
Activity: Publication peer-review and editorial work › Publication peer-review
Adjunct Professor Institute of Human Virology, University of Maryland
Peters, B. (Recipient)
Dec 2013 → Dec 2016
Activity: Other › Types of Award - Other distinction
Organising Committee and Speaker, 3rd Frontiers of Retrovirology Conference – Complex Retroviruses, Retroelements and their Hosts, Cambridge
Malim, M. (Member of programme committee)
16 Sept 2013 → 18 Sept 2013
Activity: Participating in or organising an event › Participation in conference

A DUAL APPROACH TO INCREASE ADENO-ASSOCIATED VIRAL VECTOR BIOAVAILABILITY
Jolinon, N. (Author), Henckaerts, E. (Supervisor) & Linden, M. (Supervisor), 1 Aug 2022
Student thesis: Doctoral Thesis › Doctor of Philosophy
Analysing RNA-seq datasets to determine how pre-mRNA splicing is regulated by RNA binding proteins and cis-acting elements
Hugh-White, R. (Author), Schulz, R. (Supervisor) & Swanson, C. (Supervisor), 1 Jan 2021
Student thesis: Doctoral Thesis › Doctor of Philosophy

File
Antibody mediated cross-reactivity of nonself pathogen glycans and the HIV-1 Envelope
Huettner, I. (Author), Doores, K. (Supervisor) & Wagner, G. (Supervisor), 1 Feb 2021
Student thesis: Doctoral Thesis › Doctor of Philosophy

Beit Memorial Research Fellowship
Carlton, J. (Recipient), 2006
Prize: Fellowship awarded competitively
Charles H. Revson Fellowship in Biomedical Sciences. Postdoctoral fellowship providing 2-year salary and $30,000 for research expenses.
Henckaerts, E. (Recipient), 2001
Prize: Fellowship awarded competitively
DSc honoris causa, University of Bristol
Malim, M. (Recipient), 13 Jul 2010
Prize: Honorary degree

COVID-19 and systemic lupus erythematosus genetics: a balance between autoimmune disease risk and protection against infection
Wang, Y., Guga, S., Wu, K., Khaw, Z., Tzoumkas, K., Tombleson, P., E. Comeau, M., D. Langefeld, C., Cunninghame Graham, D., Morris, D. & Vyse, T., King's College London, 30 Sept 2022
DOI: 10.18742/19758484, https://kcl.figshare.com/articles/dataset/COVID-19_and_systemic_lupus_erythematosus_genetics_a_balance_between_autoimmune_disease_risk_and_protection_against_infection/19758484
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Infectious Diseases

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Collaborations and top research areas from the last five years

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Nicole Acuti

Monica Agromayor

Nathalia Almeida Dos Santos

Accelarated immune ageing is associated with COVID-19 disease severity

A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease

Antibodies to the RBD of SARS-CoV-2 spike mediate productive infection of primary human macrophages

Translating science into the clinic - new approaches and tools for predicting risk of preterm birth

Generation of human CAR-T cells with tissue-resident memory features for improved treatment of hepatocellular carcinoma

Improving therapeutic success by directing CAR-T cell metabolism through co-stimulation

Cell Reports Medicine (Journal)

Adjunct Professor Institute of Human Virology, University of Maryland

Organising Committee and Speaker, 3rd Frontiers of Retrovirology Conference – Complex Retroviruses, Retroelements and their Hosts, Cambridge

A DUAL APPROACH TO INCREASE ADENO-ASSOCIATED VIRAL VECTOR BIOAVAILABILITY

Analysing RNA-seq datasets to determine how pre-mRNA splicing is regulated by RNA binding proteins and cis-acting elements

Antibody mediated cross-reactivity of nonself pathogen glycans and the HIV-1 Envelope

Beit Memorial Research Fellowship

Charles H. Revson Fellowship in Biomedical Sciences. Postdoctoral fellowship providing 2-year salary and $30,000 for research expenses.

DSc honoris causa, University of Bristol

COVID-19 and systemic lupus erythematosus genetics: a balance between autoimmune disease risk and protection against infection

Infectious Diseases

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Collaborations and top research areas from the last five years

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