Adrian Hayday

2022

Normality sensing licenses local T cells for innate-like tissue surveillance

McKenzie, D. R., Hart, R., Bah, N., Ushakov, D. S., Muñoz-Ruiz, M., Feederle, R. & Hayday, A. C., Mar 2022, In: Nature Immunology. 23, 3, p. 411-422 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Citations (Scopus)

2021

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H. D., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., Bacher, P., Bari, S., Barnaba, V., Barros-Martins, J., Baumjohann, D., Beccaria, C. G., Bernardo, D., Boardman, D. A., Borger, J. & Böttcher, C. & 173 others, Brockmann, L., Burns, M., Busch, D. H., Cameron, G., Cammarata, I., Cassotta, A., Chang, Y., Chirdo, F. G., Christakou, E., Čičin-Šain, L., Cook, L., Corbett, A. J., Cornelis, R., Cosmi, L., Davey, M. S., De Biasi, S., De Simone, G., del Zotto, G., Delacher, M., Di Rosa, F., Santo, J. D., Diefenbach, A., Dong, J., Dörner, T., Dress, R. J., Dutertre, C. A., Eckle, S. B. G., Eede, P., Evrard, M., Falk, C. S., Feuerer, M., Fillatreau, S., Fiz-Lopez, A., Follo, M., Foulds, G. A., Fröbel, J., Gagliani, N., Galletti, G., Gangaev, A., Garbi, N., Garrote, J. A., Geginat, J., Gherardin, N. A., Gibellini, L., Ginhoux, F., Godfrey, D. I., Gruarin, P., Haftmann, C., Hansmann, L., Harpur, C. M., Hayday, A. C., Heine, G., Hernández, D. C., Herrmann, M., Hoelsken, O., Huang, Q., Huber, S., Huber, J. E., Huehn, J., Hundemer, M., Hwang, W. Y. K., Iannacone, M., Ivison, S. M., Jäck, H. M., Jani, P. K., Keller, B., Kessler, N., Ketelaars, S., Knop, L., Knopf, J., Koay, H. F., Kobow, K., Kriegsmann, K., Kristyanto, H., Krueger, A., Kuehne, J. F., Kunze-Schumacher, H., Kvistborg, P., Kwok, I., Latorre, D., Lenz, D., Levings, M. K., Lino, A. C., Liotta, F., Long, H. M., Lugli, E., MacDonald, K. N., Maggi, L., Maini, M. K., Mair, F., Manta, C., Manz, R. A., Mashreghi, M. F., Mazzoni, A., McCluskey, J., Mei, H. E., Melchers, F., Melzer, S., Mielenz, D., Monin, L., Moretta, L., Multhoff, G., Muñoz, L. E., Muñoz-Ruiz, M., Muscate, F., Natalini, A., Neumann, K., Ng, L. G., Niedobitek, A., Niemz, J., Almeida, L. N., Notarbartolo, S., Ostendorf, L., Pallett, L. J., Patel, A. A., Percin, G. I., Peruzzi, G., Pinti, M., Pockley, A. G., Pracht, K., Prinz, I., Pujol-Autonell, I., Pulvirenti, N., Quatrini, L., Quinn, K. M., Radbruch, H., Rhys, H., Rodrigo, M. B., Romagnani, C., Saggau, C., Sakaguchi, S., Sallusto, F., Sanderink, L., Sandrock, I., Schauer, C., Scheffold, A., Scherer, H. U., Schiemann, M., Schildberg, F. A., Schober, K., Schoen, J., Schuh, W., Schüler, T., Schulz, A. R., Schulz, S., Schulze, J., Simonetti, S., Singh, J., Sitnik, K. M., Stark, R., Starossom, S., Stehle, C., Szelinski, F., Tan, L., Tarnok, A., Tornack, J., Tree, T. I. M., van Beek, J. J. P., van de Veen, W., van Gisbergen, K., Vasco, C., Verheyden, N. A., von Borstel, A., Ward-Hartstonge, K. A., Warnatz, K., Waskow, C., Wiedemann, A., Wilharm, A., Wing, J., Wirz, O., Wittner, J., Yang, J. H. M. & Yang, J., Dec 2021, In: European Journal of Immunology. 51, 12, p. 2708-3145 438 p.

Research output: Contribution to journal › Article › peer-review

Open Access

221 Citations (Scopus)

OMIP-079: Cell cycle of CD4⁺ and CD8⁺ naïve/memory T cell subsets, and of Treg cells from mouse spleen

Natalini, A., Simonetti, S., Favaretto, G., Peruzzi, G., Antonangeli, F., Santoni, A., Munoz-Ruiz, M., Hayday, A. & Di Rosa, F., Dec 2021, In: Cytometry Part A. 99, 12, p. 1171-1175 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Citations (Scopus)

Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study

Monin, L., Laing, A. G., Muñoz-Ruiz, M., McKenzie, D. R., Del Molino Del Barrio, I., Alaguthurai, T., Domingo-Vila, C., Hayday, T. S., Graham, C., Seow, J., Abdul-Jawad, S., Kamdar, S., Harvey-Jones, E., Graham, R., Cooper, J., Khan, M., Vidler, J., Kakkassery, H., Sinha, S. & Davis, R. & 24 others, Dupont, L., Francos Quijorna, I., O'Brien-Gore, C., Lee, P. L., Eum, J., Conde Poole, M., Joseph, M., Davies, D., Wu, Y., Swampillai, A., North, B. V., Montes, A., Harries, M., Rigg, A., Spicer, J., Malim, M. H., Fields, P., Patten, P., Di Rosa, F., Papa, S., Tree, T., Doores, K. J., Hayday, A. C. & Irshad, S., Jun 2021, In: The Lancet Oncology. 22, 6, p. 765-778 14 p.

Research output: Contribution to journal › Article › peer-review

448 Citations (Scopus)

SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care

Gutmann, C., Takov, K., Burnap, S. A., Singh, B., Ali, H., Theofilatos, K., Reed, E., Hasman, M., Nabeebaccus, A., Fish, M., McPhail, M. J., O'Gallagher, K., Schmidt, L. E., Cassel, C., Rienks, M., Yin, X., Auzinger, G., Napoli, S., Mujib, S. F. & Trovato, F. & 17 others, Sanderson, B., Merrick, B., Niazi, U., Saqi, M., Dimitrakopoulou, K., Fernández-Leiro, R., Braun, S., Kronstein-Wiedemann, R., Doores, K. J., Edgeworth, J. D., Shah, A. M., Bornstein, S. R., Tonn, T., Hayday, A. C., Giacca, M., Shankar-Hari, M. & Mayr, M., Dec 2021, In: Nature Communications. 12, 1, 3406.

Research output: Contribution to journal › Article › peer-review

Open Access

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114 Citations (Scopus)

226 Downloads (Pure)

2020

A dynamic COVID-19 immune signature includes associations with poor prognosis

Laing, A. G., Lorenc, A., del Molino del Barrio, I., Das, A., Fish, M., Monin, L., Muñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., Kamdar, S., Joseph, M., Davies, D., Davis, R., Jennings, A., Zlatareva, I., Vantourout, P., Wu, Y., Sofra, V. & Cano, F. & 30 others, Greco, M., Theodoridis, E., Freedman, J., Gee, S., Chan, J. N. E., Ryan, S., Bugallo-Blanco, E., Peterson, P., Kisand, K., Haljasmägi, L., Chadli, L., Moingeon, P., Martinez, L., Merrick, B., Bisnauthsing, K., Brooks, K., Ibrahim, M. A. A., Mason, J., Lopez Gomez, F., Babalola, K., Abdul-Jawad, S., Cason, J., Mant, C., Seow, J., Graham, C., Doores, K. J., Di Rosa, F., Edgeworth, J., Shankar-Hari, M. & Hayday, A. C., 1 Oct 2020, In: Nature Medicine. 26, 10, p. 1623-1635 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

644 Citations (Scopus)

Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments

Jandke, A., Melandri, D., Monin, L., Ushakov, D. S., Laing, A. G., Vantourout, P., East, P., Nitta, T., Narita, T., Takayanagi, H., Feederle, R. & Hayday, A., 1 Dec 2020, In: Nature Communications. 11, 1, 3769.

Research output: Contribution to journal › Article › peer-review

Open Access

41 Citations (Scopus)

Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19

Haljasmägi, L., Salumets, A., Rumm, A. P., Jürgenson, M., Krassohhina, E., Remm, A., Sein, H., Kareinen, L., Vapalahti, O., Sironen, T., Peterson, H., Milani, L., Tamm, A., Hayday, A., Kisand, K. & Peterson, P., Dec 2020, In: Scientific Reports. 10, 1, 20533.

Research output: Contribution to journal › Article › peer-review

Open Access

62 Citations (Scopus)

γδ T cells compose a developmentally regulated intrauterine population and protect against vaginal candidiasis

Monin, L., Ushakov, D. S., Arnesen, H., Bah, N., Jandke, A., Muñoz-Ruiz, M., Carvalho, J., Joseph, S., Almeida, B. C., Green, M. J., Nye, E., Hatano, S., Yoshikai, Y., Curtis, M., Carlsen, H., Steinhoff, U., Boysen, P. & Hayday, A., 1 Nov 2020, In: Mucosal Immunology. 13, 6, p. 969-981 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

36 Citations (Scopus)

2018

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology

Vantourout, P., Laing, A., Woodward, M. J., Zlatareva, I., Apolonia, L., Jones, A. W., Snijders, A. P., Malim, M. H. & Hayday, A. C., 30 Jan 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 5, p. 1039-1044 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

119 Citations (Scopus)

221 Downloads (Pure)

2016

AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

Meyer, S., Woodward, M., Hertel, C., Vlaicu, P., Haque, Y., Kärner, J., Macagno, A., Onuoha, S. C., Fishman, D., Peterson, H., Metsküla, K., Uibo, R., Jäntti, K., Hokynar, K., Wolff, A. S. B., Meloni, A., Kluger, N., Husebye, E. S., Podkrajsek, K. T. & Battelino, T. & 7 others, Bratanic, N., Peet, A., Krohn, K., Ranki, A., Peterson, P., Kisand, K. & Hayday, A., 28 Jul 2016, In: Cell. 166, 3, p. 582-595 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

212 Citations (Scopus)

353 Downloads (Pure)

Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments

Di Marco Barros, R., Roberts, N., Dart, R., Vantourout, P., Jandke, A., Nussbaumer, O., Deban, L., Cipolat, S., Hart, R., Iannitto, M., Laing, A., Spencer-Dene, B., East, P., Gibbons, D., Irving, P., Pereira, P., Steinhoff, U. & Hayday, A., 22 Sept 2016, In: Cell. 167, 1, p. 203-218.e17

Research output: Contribution to journal › Article › peer-review

Open Access

File

258 Citations (Scopus)

370 Downloads (Pure)

2015

Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

Swamy, M., Abeler-Dörner, L., Chettle, J., Mahlakõiv, T., Goubau, D., Chakravarty, P., Ramsay, G., Reis E Sousa, C., Staeheli, P., Blacklaws, B. A., Heeney, J. L. & Hayday, A. C., 19 May 2015, In: Nature Communications. 6, 7090.

Research output: Contribution to journal › Article › peer-review

Open Access

57 Citations (Scopus)

2014

Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants

Gibbons, D., Fleming, P., Virasami, A., Michel, M.-L., Sebire, N. J., Costeloe, K., Carr, R., Klein, N. & Hayday, A., 1 Oct 2014, In: Nature Medicine. 20, 10, p. 1206-1210 5 p.

Research output: Contribution to journal › Article › peer-review

162 Citations (Scopus)

2013

Receptor for Advanced Glycation End Products Contributes to Postnatal Pulmonary Development and Adult Lung Maintenance Program in Mice

Fineschi, S., De Cunto, G., Facchinetti, F., Civelli, M., Imbimbo, B. P., Carnini, C., Villetti, G., Lunghi, B., Stochino, S., Gibbons, D. L., Hayday, A., Lungarella, G. & Cavarra, E., Feb 2013, In: American Journal of Respiratory Cell and Molecular Biology. 48, 2, p. 164-171 8 p., N/A.

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

2012

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis

Knight, J., Spain, S. L., Capon, F., Hayday, A., Nestle, F. O., Clop, A., Wellcome Trust Case Control Consortium, Barker, J. N., Weale, M. E. & Trembath, R. C., Dec 2012, In: Human Molecular Genetics. 21, 23, p. 5185-92 8 p.

Research output: Contribution to journal › Article › peer-review

52 Citations (Scopus)

2011

Butyrophilin-like 1 encodes an enterocyte protein that selectively regulates functional interactions with T lymphocytes

Bas, A., Swamy, M., Abeler-Doerner, L., Williams, G., Pang, D. J., Barbee, S. D. & Hayday, A. C., 15 Mar 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 11, p. 4376 - 4381 6 p.

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasis

Laggner, U., Di Meglio, P., Perera, G. K., Hundhausen, C., Lacy, K. E., Ali, N., Smith, C. H., Hayday, A. C., Nickoloff, B. J. & Nestle, F. O., 1 Sept 2011, In: Journal of Immunology. 187, 5, p. 2783-2793 11 p.

Research output: Contribution to journal › Article › peer-review

283 Citations (Scopus)

Skint-1 identifies a common molecular mechanism for the development of interferon-γ-secreting versus interleukin-17-secreting γδ T cells

Turchinovich, G. & Hayday, A. C., 22 Jul 2011, In: Immunity. 35, 1, p. 59-68 10 p.

Research output: Contribution to journal › Article › peer-review

217 Citations (Scopus)

The Intraepithelial T Cell Response to NKG2D-Ligands Links Lymphoid Stress Surveillance to Atopy

Strid, J., Sobolev, O., Zafirova, B., Polic, B. & Hayday, A., 2 Dec 2011, In: Science. 334, 6060, p. 1293-1297 5 p.

Research output: Contribution to journal › Article › peer-review

126 Citations (Scopus)

2010

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

Strange, A., Capon, F., Spencer, C. C. A., Knight, J., Weale, M. E., Allen, M. H., Barton, A., Band, G., Bellenguez, C., Bergboer, J. G. M., Blackwell, J. M., Bramon, E., Bumpstead, S. J., Casas, J. P., Cork, M. J., Corvin, A., Deloukas, P., Dilthey, A., Duncanson, A. & Edkins, S. & 64 others, Estivill, X., Fitzgerald, O., Freeman, C., Giardina, E., Gray, E., Hofer, A., Hueffmeier, U., Hunt, S. E., Irvine, A. D., Jankowski, J., Kirby, B., Langford, C., Lascorz, J., Leman, J., Leslie, S., Mallbris, L., Markus, H. S., Mathew, C. G., McLean, W. H. I., McManus, R., Moessner, R., Moutsianas, L., Naluai, A. T., Nestle, F. O., Novelli, G., Onoufriadis, A., Palmer, C. N. A., Perricone, C., Pirinen, M., Plomin, R., Potter, S. C., Pujol, R. M., Rautanen, A., Riveira-Munoz, E., Ryan, A. W., Salmhofer, W., Samuelsson, L., Sawcer, S. J., Schalkwijk, J., Smith, C. H., Stahle, M., Su, Z., Tazi-Ahnini, R., Traupe, H., Viswanathan, A. C., Warren, R. B., Weger, W., Wolk, K., Wood, N., Worthington, J., Young, H. S., Zeeuwen, P. L. J. M., Hayday, A., Burden, A. D., Griffiths, C. E. M., Kere, J., Reis, A., McVean, G., Evans, D. M., Brown, M. A., Barker, J. N., Peltonen, L., Donnelly, P. & Trembath, R. C., Nov 2010, In: Nature Genetics. 42, 11, p. 985 - 990 6 p.

Research output: Contribution to journal › Article › peer-review

866 Citations (Scopus)

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

Cardone, J., Le Friec, G., Vantourout, P., Roberts, A., Fuchs, A., Jackson, I., Suddason, T., Lord, G., Atkinson, J. P., Cope, A., Hayday, A. & Kemper, C., Sept 2010, In: Nature Immunology. 11, 9, p. 862 - 871 10 p.

Research output: Contribution to journal › Article › peer-review

235 Citations (Scopus)

In vivo manipulation of Vγ9Vδ2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients

Meraviglia, S., Eberl, M., Vermijlen, D., Todaro, M., Buccheri, S., Cicero, G., La Mendola, C., Guggino, G., D'Asaro, M., Orlando, V., Scarpa, F., Roberts, A., Caccamo, N., Stassi, G., Dieli, F. & Hayday, A. C., Aug 2010, In: Clinical and Experimental Immunology. 161, 2, p. 290 - 297 8 p.

Research output: Contribution to journal › Article › peer-review

260 Citations (Scopus)

2008

Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis

Strid, J., Roberts, S. J., Filler, R. B., Lewis, J. M., Kwong, B. Y., Schpero, W., Kaplan, D. H., Hayday, A. C. & Girardi, M., Feb 2008, In: Nature Immunology. 9, 2, p. 146 - 154 9 p.

Research output: Contribution to journal › Article › peer-review

221 Citations (Scopus)

Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gamma delta T cells

Boyden, L. M., Lewis, J. M., Barbee, S. D., Bas, A., Girardi, M., Hayday, A. C., Tigelaar, R. E. & Lifton, R. P., May 2008, In: Nature Genetics. 40, 5, p. 656 - 662 7 p.

Research output: Contribution to journal › Article › peer-review

244 Citations (Scopus)

2007

Distinct cytokine-driven responses of activated blood gamma delta T cells: Insights into unconventional T cell pleiotropy

Vermijlen, D., Ellis, P., Langford, C., Klein, A., Engel, R., Willimann, K., Jomaa, H., Hayday, A. C. & Eberl, M., 2007, In: Journal of Immunology. 178, 7, p. 4304 - 4314 11 p.

Research output: Contribution to journal › Article › peer-review

122 Citations (Scopus)

2005

Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance

Oppenheim, D. E., Roberts, S. J., Clarke, S. L., Filler, R., Lewis, J. M., Tigelaar, R. E., Girardi, M. & Hayday, A. C., Sept 2005, In: Nature Immunology. 6, 9, p. 928 - 937 10 p.

Research output: Contribution to journal › Article › peer-review

365 Citations (Scopus)

2001

Regulation of cutaneous malignancy by gamma delta T cells

Girardi, M., Oppenheim, D. E., Steele, C. R., Lewis, J. M., Glusac, E., Filler, R., Hobby, P., Sutton, B., Tigelaar, R. E. & Hayday, A. C., 19 Oct 2001, In: Science. 294, 5542, p. 605 - 609 5 p.

Research output: Contribution to journal › Article › peer-review

850 Citations (Scopus)

2000

Constitutive activation of NF-kappa B and T-cell leukemia/lymphoma in Notch3 transgenic mice

Bellavia, D., Campese, A. F., Alesse, E., Vacca, A., Felli, M. P., Balestri, A., Stoppacciaro, A., Tiveron, C., Tatangelo, L., Giovarelli, M., Gaetano, C., Ruco, L., Hoffman, E. S., Hayday, A. C., Lendahl, U., Frati, L., Gulino, A. & Screpanti, I., 2000, In: EMBO Journal. 19, 13, p. 3337 - 3348 12 p.

Research output: Contribution to journal › Article › peer-review

314 Citations (Scopus)

The ins and outs of body surface immunology

Hayday, A. & Viney, J. L., 6 Oct 2000, In: Science. 290, 5489, p. 97 - 100 4 p.

Research output: Contribution to journal › Editorial › peer-review

48 Citations (Scopus)

Adrian Hayday

Research output

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