Research output per year
Research output per year
Personal profile
Research interests
We are studying the development and function of different subsets of T lymphocytes in the lung, with a special interest in the role of CD8 T cells and regulatory T cells. An understanding of immune regulation is helping us to develop vaccines to suppress the allergic inflammatory response which is critical in asthma. We are also investigating how poor hygiene and infection might prevent allergic disease.
Research interests (short)
T cell subsets; immune regulation; allergic inflammation.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, United Medical and Dental Schools (UMDS)
Award Date: 1 Jan 1994
Bachelor of Science, King's College London
Award Date: 1 Jan 1988
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Research output
- 2 Article
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Absence of Galectin-1 accelerates CD8(+) T cell-mediated graft rejection
Moreau, A., Noble, A., Ratnasothy, K., Chai, J.-G., Deltour, L., Cuturi, M.-C., Simpson, E., Lechler, R. & Lombardi, G., Nov 2012, In: European Journal of Immunology. 42, 11, p. 2881-2888 8 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling
Zhao, J., Lloyd, C. M. & Noble, A., 2012, (E-pub ahead of print) In: Mucosal Immunology. 6, 2, p. 335-346 12 p.Research output: Contribution to journal › Article › peer-review
184 Citations (Scopus)