Does COVID-19 affect the brain? Gaining mechanistic insight “in vitro” on how brain cell function is disrupted upon exposure to serum from COVID-19 patients with neurological symptoms

Borsini, A. (Primary Investigator), Lechler, R. (Co-Investigator), Pariante, C. (Co-Investigator), Srivastava, D. (Co-Investigator), Thuret, S. (Co-Investigator), Vernon, A. (Co-Investigator) & Williams, F. (Co-Investigator)

Rosetrees Trust

1/02/2021 → 31/08/2022

Project: Research

Targeting Nox2 to improve regulatory T cell function and immune tolerance in heart transplantation

Shah, A. (Primary Investigator), Cellone Trevelin, S. (Co-Investigator), Lombardi, G. (Co-Investigator), Ivetic, A. (Co-Investigator) & Lechler, R. (Co-Investigator)

BHF British Heart Foundation

10/08/2018 → 9/08/2021

Project: Research

Targeting recipient antigen-presenting cells with sialic acid-modified alloantigen to promote transplantation tolerance

Lombardi, G. (Primary Investigator), Lechler, R. (Co-Investigator) & Smyth, L. A. (Co-Investigator)

BHF British Heart Foundation

1/10/2017 → 30/09/2020

Project: Research

Defining the mechanisms underlying the role of regulatory T cells in the establishment of tolerance

Lombardi, G. (Primary Investigator), Sanchez Fueyo, A. (Primary Investigator), Douiri, A. (Co-Investigator), Lechler, R. (Co-Investigator) & Martinez-Llordella, M. (Co-Investigator)

9/01/2017 → 8/01/2022

Project: Research

Thymus derived Tregs expanded in vitro as a treatment for paediatric heart transplant patients to prevent cardiac allograft vasculopathy.

Lombardi, G. (Primary Investigator), Botnar, R. (Co-Investigator), Lechler, R. (Co-Investigator) & Scotta, C. (Co-Investigator)

BHF British Heart Foundation

1/01/2017 → 31/12/2018

Project: Research