Research output per year
Research output per year
- 11 results
Search results
-
2004
Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach
Hay, D. G., Sathasivam, K., Tobaben, S., Stahl, B., Marber, M., Mestril, R., Mahal, A., Smith, D. L., Woodman, B. & Bates, G. P., 1 Jul 2004, In: Human Molecular Genetics. 13, 13, p. 1389 - 1405 17 p.Research output: Contribution to journal › Article › peer-review
289 Citations (Scopus) -
2003
Minocycline and doxycycline are not beneficial in a model of Huntington's disease
Smith, D. L., Woodman, B., Mahal, A., Sathasivam, K., Ghazi-Noori, S., Lowden, P. A. S., Bates, G. P. & Hockly, E., 1 Aug 2003, In: Annals of Neurology. 54, 2, p. 186 - 196 11 p.Research output: Contribution to journal › Article › peer-review
150 Citations (Scopus) -
Standardization and statistical approaches to therapeutic trials in the R6/2 mouse
Hockly, E., Woodman, B., Mahal, A., Lewis, C. M. & Bates, G., 30 Sept 2003, In: Brain Research Bulletin. 61, 5, p. 469 - 479 11 p.Research output: Contribution to journal › Article › peer-review
122 Citations (Scopus) -
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
Hockly, E., Richon, V. M., Woodman, B., Smith, D. L., Zhou, X. B., Rosa, E., Sathasivam, K., Ghazi-Noori, S., Mahal, A., Lowden, P. A. S., Steffan, J. S., Marsh, J. L., Thompson, L. M., Lewis, C. M., Marks, P. A. & Bates, G. P., 18 Feb 2003, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 4, p. 2041 - 2046 6 p.Research output: Contribution to journal › Article › peer-review
774 Citations (Scopus) -
2002
Abnormal phosphorylation of synapsin I predicts a neuronal transmission impairment in the R6/2 Huntington's disease transgenic mice
Lievens, J. C., Woodman, B., Mahal, A. & Bates, G. P., 2002, In: Molecular and Cellular Neurosciences. 20, 4, p. 638 - 648 11 p.Research output: Contribution to journal › Article › peer-review
73 Citations (Scopus) -
Environmental enrichment slows disease progression in R61/2 Huntington's disease mice
Hockly, E., Cordery, P. M., Woodman, B., Mahal, A., van Dellen, A., Blakemore, C., Lewis, C. M., Hannan, A. J. & Bates, G. P., 2002, In: Annals of Neurology. 51, 2, p. 235 - 242 8 p.Research output: Contribution to journal › Article › peer-review
299 Citations (Scopus) -
2001
Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients
Sathasivam, K., Woodman, B., Mahal, A., Bertaux, F., Wanker, E. E., Shima, D. T. & Bates, G. P., 2001, In: Human Molecular Genetics. 10, 21, p. 2425 - 2435 11 p.Research output: Contribution to journal › Article › peer-review
93 Citations (Scopus) -
Impaired glutamate uptake in the R6 Huntington's disease transgenic mice
Lievens, J. C., Woodman, B., Mahal, A., Spasic-Boscovic, O., Samuel, D., Goff, L. K. L. & Bates, G. P., 2001, In: Neurobiology of Disease. 8, 5, p. 807 - 821 15 p.Research output: Contribution to journal › Article › peer-review
262 Citations (Scopus) -
Inhibition of polyglutamine aggregation in R6/2 HD brain slices - Complex dose-response profiles
Smith, D. L., Portier, R., Woodman, B., Hockly, E., Mahal, A., Klunk, W. E., Li, X. J., Wanker, E., Murray, K. D. & Bates, G. P., 2001, In: Neurobiology of Disease. 8, 6, p. 1017 - 1026 10 p.Research output: Contribution to journal › Article › peer-review
65 Citations (Scopus) -
2000
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
Tabrizi, S. J., Workman, J., Hart, P. E., Mangiarini, L., Mahal, A., Bates, G., Cooper, J. M. & Schapira, A. H. V., Jan 2000, In: Annals of Neurology. 47, 1, p. 80 - 86 7 p.Research output: Contribution to journal › Article › peer-review
Open Access316 Citations (Scopus) -
1997
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
Mangiarini, L., Sathasivam, K., Mahal, A., Mott, R., Seller, M. & Bates, G. P., Feb 1997, In: Nature Genetics. 15, 2, p. 197-200 4 p.Research output: Contribution to journal › Article › peer-review
270 Citations (Scopus)