Research output per year
Research output per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Targeted disruption of the mouse TRAP220 gene, Imperial College London
Award Date: 1 Jan 2002
Bachelor of Science, Queen Mary University of London
Award Date: 1 Jan 1998
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Dive into the research topics where Christian Landles is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease
Sathasivam, K., Neueder, A., Gipson, T. A., Landles, C., Benjamin, A. C., Bondulich, M. K., Smith, D. L., Faull, R. L. M., Roos, R. A. C., Howland, D., Detloff, P. J., Housman, D. E. & Bates, G. P., 5 Feb 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 6, p. 2366-2370 5 p.Research output: Contribution to journal › Article › peer-review
385 Citations (Scopus) -
HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration
Mielcarek, M., Landles, C., Weiss, A., Bradaia, A., Seredenina, T., Inuabasi, L., Osborne, G., Touller, C., Butler, R., Robertson, J., Franklin, S., Smith, D. L., Park, L., Marks, P. A., Wanker, E. E., Olson, E. N., Luthi-Carter, R., van der Putten, H., Beaumont, V. & Bates, G., 2013, (E-pub ahead of print) In: PL o S Biology. 11, 11, e1001717.Research output: Contribution to journal › Article › peer-review
140 Citations (Scopus) -
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Bjorkqvist, M., Wild, E. J., Thiele, J., Silvestroni, A., Andre, R., Lahiri, N., Raibon, E., Lee, R. V., Benn, C. L., Soulet, D., Magnusson, A., Woodman, B., Landles, C., Pouladi, M. A., Hayden, M. R., Khalili-Shirazi, A., Lowdell, M. W., Brundin, P., Bates, G. P. & Leavitt, B. R. & 2 others, , 4 Aug 2008, In: Journal of Experimental Medicine. 205, 8, p. 1869 - 1877 9 p.Research output: Contribution to journal › Article › peer-review
518 Citations (Scopus) -
Huntingtin and the molecular pathogenesis of Huntington's disease.
Landles, C. & Bates, G. P., Oct 2004, In: EMBO Reports. 5, 10, p. 958 - 963 6 p.Research output: Contribution to journal › Literature review › peer-review
378 Citations (Scopus)