HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

Michal Mielcarek; Christian Landles; Andreas Weiss; Amyaouch Bradaia; Tamara Seredenina; Linda Inuabasi; Georgina Osborne; Chrystelle Touller; Rachel Butler; Janette Robertson; Sophie Franklin; Donna L. Smith; Larry Park; Paul A. Marks; Erich E. Wanker; Eric N. Olson; Ruth Luthi-Carter; Herman van der Putten; Vahri Beaumont; Gillian Bates

doi:10.1371/journal.pbio.1001717

HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

Michal Mielcarek, Christian Landles, Andreas Weiss, Amyaouch Bradaia, Tamara Seredenina, Linda Inuabasi, Georgina Osborne, Chrystelle Touller, Rachel Butler, Janette Robertson, Sophie Franklin, Donna L. Smith, Larry Park, Paul A. Marks, Erich E. Wanker, Eric N. Olson, Ruth Luthi-Carter, Herman van der Putten, Vahri Beaumont, Gillian Bates

Medical & Molecular Genetics

Research output: Contribution to journal › Article › peer-review

140 Citations (Scopus)

Original language	English
Article number	e1001717
Journal	PL o S Biology
Volume	11
Issue number	11
DOIs	https://doi.org/10.1371/journal.pbio.1001717
Publication status	E-pub ahead of print - 2013

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10.1371/journal.pbio.1001717

Cite this

Mielcarek, M., Landles, C., Weiss, A., Bradaia, A., Seredenina, T., Inuabasi, L., Osborne, G., Touller, C., Butler, R., Robertson, J., Franklin, S., Smith, D. L., Park, L., Marks, P. A., Wanker, E. E., Olson, E. N., Luthi-Carter, R., van der Putten, H., Beaumont, V., & Bates, G. (2013). HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration. PL o S Biology, 11(11), Article e1001717. Advance online publication. https://doi.org/10.1371/journal.pbio.1001717

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title = "HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration",

author = "Michal Mielcarek and Christian Landles and Andreas Weiss and Amyaouch Bradaia and Tamara Seredenina and Linda Inuabasi and Georgina Osborne and Chrystelle Touller and Rachel Butler and Janette Robertson and Sophie Franklin and Smith, {Donna L.} and Larry Park and Marks, {Paul A.} and Wanker, {Erich E.} and Olson, {Eric N.} and Ruth Luthi-Carter and {van der Putten}, Herman and Vahri Beaumont and Gillian Bates",

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Mielcarek, M , Landles, C, Weiss, A, Bradaia, A, Seredenina, T, Inuabasi, L , Osborne, G, Touller, C, Butler, R , Robertson, J , Franklin, S, Smith, DL, Park, L, Marks, PA, Wanker, EE, Olson, EN, Luthi-Carter, R, van der Putten, H, Beaumont, V & Bates, G 2013, 'HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration', PL o S Biology, vol. 11, no. 11, e1001717. https://doi.org/10.1371/journal.pbio.1001717

TY - JOUR

T1 - HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration

AU - Mielcarek, Michal

AU - Landles, Christian

AU - Weiss, Andreas

AU - Bradaia, Amyaouch

AU - Seredenina, Tamara

AU - Inuabasi, Linda

AU - Osborne, Georgina

AU - Touller, Chrystelle

AU - Butler, Rachel

AU - Robertson, Janette

AU - Franklin, Sophie

AU - Smith, Donna L.

AU - Park, Larry

AU - Marks, Paul A.

AU - Wanker, Erich E.

AU - Olson, Eric N.

AU - Luthi-Carter, Ruth

AU - van der Putten, Herman

AU - Beaumont, Vahri

AU - Bates, Gillian

PY - 2013

Y1 - 2013

U2 - 10.1371/journal.pbio.1001717

DO - 10.1371/journal.pbio.1001717

M3 - Article

SN - 1544-9173

VL - 11

JO - PL o S Biology

JF - PL o S Biology

IS - 11

M1 - e1001717

ER -