Research output per year
Research output per year
- 36 results
Search results
-
2016
C. elegans flavin-containing monooxygenase-4 is essential for osmoregulation in hypotonic stress
Hirani, N., Westenberg, M., Seed, P. T. & Dolphin, C. T., 27 Apr 2016, (E-pub ahead of print) In: Biology Open. 5, 5, p. 537-549Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)251 Downloads (Pure) -
2013
A simplified counter-selection recombineering protocol for creating fluorescent protein reporter constructs directly from C. elegans fosmid genomic clones
Hirani, N., Westenberg, M., Gami, M., Davis, P., Hope, I. & Dolphin, C., 2013, In: BMC BIOTECHNOLOGY. 13, 1, p. N/A 13 p., N/A.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
The significance of alternative transcripts for Caenorhabditis elegans transcription factor genes, based on expression pattern analysis
Craig, H. L., Wirtz, J., Bamps, S., Dolphin, C. T. & Hope, I. A., 15 Apr 2013, In: BMC GENOMICS. 14, 20 p., 249.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
2012
Seamless replacement of Autographa californica multiple nucleopolyhedrovirus gp64 with each of five novel type II alphabaculovirus fusion sequences generates pseudotyped virus that fails to transduce mammalian cells
Westenberg, M., Soedling, H. M., Hirani, N., Nicholson, L. J., Mann, D. A. & Dolphin, C. T., Jul 2012, In: Journal of General Virology. 93, PART 7, p. 1583-1590 8 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
2010
Counter-selection recombineering of the baculovirus genome: a strategy for seamless modification of repeat-containing BACs
Westenberg, M., Soedling, H. M., Mann, D. A., Nicholson, L. J. & Dolphin, C. T., 9 Jul 2010, In: Nucleic Acids Research. 38, 16, e166.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Escherichia coli MW005: lambda Red-mediated recombineering and copy-number induction of oriV-equipped constructs in a single host
Westenberg, M., Bamps, S., Soedling, H., Hope, I. A. & Dolphin, C. T., 29 Mar 2010, In: BMC BIOTECHNOLOGY. 10, 27, 27.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
2006
Caenorhabditis elegans reporter fusion genes generated by seamless modification of large genomic DNA clones
Dolphin, C. T. & Hope, I. A., 2006, In: Nucleic Acids Research. 34, 9, e72.Research output: Contribution to journal › Article › peer-review
60 Citations (Scopus) -
2005
RNA interference mediated in human primary cells via recombinant baculoviral vectors
Nicholson, L. J., Philippe, M., Paine, A. J., Mann, D. A. & Dolphin, C. T., Apr 2005, In: Molecular Therapy. 11, 4, p. 638 - 644 7 p.Research output: Contribution to journal › Article › peer-review
61 Citations (Scopus) -
The fmo genes of Caenorhabditis elegans and C-briggsae: characterisation, gene expression and comparative genomic analysis
Petalcorin, M. I. R., Joshua, G. W., Agapow, P. M. & Dolphin, C. T., 14 Feb 2005, In: Gene. 346, p. 83 - 96 14 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
2002
Genetic polymorphisms of flavin-containing monooxygenase (FMO). [Review] [30 refs]
Krueger, S. K., Williams, D. E., Yueh, M. F., Martin, S. R., Hines, R. N., Raucy, J. L., Dolphin, C. T., Shephard, E. A. & Phillips, I. R., 2002, In: Drug Metabolism Reviews. 34, 3, p. 523 - 532 10 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
The peroxisome proliferator-activated receptor alpha-selective activator ciprofibrate upregulates expression of genes encoding fatty acid oxidation and ketogenesis enzymes in rat brain
Cullingford, T. E., Dolphin, C. T. & Sato, H., 2002, In: Neuropharmacology. 42, 5, p. 724 - 730 7 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
2001
Editorial
Fry, J., Haselden, J., Canesi, L., De Pomerai, D., Kortenkamp, A., Cocker, J., Lindstrom-Seppa, P., Hylland, K., Di Giulio, R. T., Panter, G., Wild, C., De Matteis, F., Benowitz, N., Bennetau-Pelissero, C., Dolphin, C., Gooderham, N., Shuker, D., Viarengo, A., Porte, C. & Phillips, D. & 9 others, , 2001, In: BIOMARKERS. 6, 6, p. 387 1 p.Research output: Contribution to journal › Article › peer-review
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Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450
Janmohamed, A., Dolphin, C. T., Phillips, I. R. & Shephard, E. A., 15 Sept 2001, In: Biochemical Pharmacology. 62, 6, p. 777 - 786 10 p.Research output: Contribution to journal › Article › peer-review
109 Citations (Scopus) -
2000
A novel mutation in the flavin-containing monooxygenase 3 gene, FM03, that causes fish-odour syndrome: activity of the mutant enzyme assessed by proton NMR spectroscopy
Murphy, H. C., Dolphin, C. T., Janmohamed, A., Holmes, H. C., Michelakakis, H., Shephard, E. A., Chalmers, R. A., Phillips, I. R. & Iles, R. A., 2000, In: Pharmacogenetics. 10, 5, p. 439 - 451 13 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Characterization and enzyme expression analysis of FMO3 mutations in trimethylaminuria using proton NMR spectroscopy
Iles, R. A., Murphy, H. C., Dolphin, C. T., Janmohamed, A., Holmes, H. C., Michelakakis, H., Shephard, E. A., Chalmers, R. A. & Phillips, I. R., 2000, In: Journal of Inherited Metabolic Disease. 23, Supplement 1, p. 281 1 p.Research output: Contribution to journal › Article › peer-review
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Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FM03) gene in patients with fish-odour syndrome
Dolphin, C. T., Janmohamed, A., Smith, R. L., Shephard, E. A. & Phillips, I. R., 2000, In: Pharmacogenetics. 10, 9, p. 799 - 807 9 p.Research output: Contribution to journal › Article › peer-review
58 Citations (Scopus) -
Ethnic differences in human flavin-containing monooxygenase 2 (FMO2) polymorphisms: detection of expressed protein in African-Americans
Whetstine, J. R., Yueh, M. F., McCarver, D. G., Williams, D. E., Park, C. S., Kang, J. H., Cha, Y. N., Dolphin, C. T., Shephard, E. A., Phillips, I. R. & Hines, R. N., 1 Nov 2000, In: Toxicology and Applied Pharmacology. 168, 3, p. 216 - 224 9 p.Research output: Contribution to journal › Article › peer-review
85 Citations (Scopus) -
Regulation of the ketogenic enzyme mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in astrocytes and meningeal fibroblasts: Implications in normal brain development and seizure neuropathologies
Cullingford, T. E., Bhakoo, K. K., Peuchen, S., Dolphin, C. T. & Clark, J. B., 2000, In: Advances in Experimental Medicine And Biology. 466, p. 241 - 251 11 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Sequence variation in the human flavin-containing monooxygenase 3 gene (FMO3): Identification by denaturing-high performance liquid chromatography (DHPLC)
Charon, C. M. & Dolphin, C. T., 2000, In: Biochemical Society Transactions. 28, 5, p. A435Research output: Contribution to journal › Article › peer-review
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1998
Distribution of mRNAs encoding the peroxisome proliferator-activated receptor alpha, beta, and gamma and the retinoid X receptor alpha, beta, and gamma in rat central nervous system
Cullingford, T. E., Bhakoo, K., Peuchen, S., Dolphin, C. T., Patel, R. & Clark, J. B., Apr 1998, In: Journal of Neurochemistry. 70, 4, p. 1366-75 10 p.Research output: Contribution to journal › Article › peer-review
210 Citations (Scopus) -
Molecular cloning of rat mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase and detection of the corresponding mRNA and of those encoding the remaining enzymes comprising the ketogenic 3-hydroxy-3-methylglutaryl-CoA cycle in central nervous system of suckling rat
Cullingford, T. E., Dolphin, C. T., Bhakoo, K. K., Peuchen, S., Canevari, L. & Clark, J. B., 15 Jan 1998, In: Biochemical Journal. 329 ( Pt 2), p. 373-81 9 p.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus) -
The flavin-containing monooxygenase 2 gene (FMO2) of humans, but not of other primates, encodes a truncated, nonfunctional protein
Dolphin, C. T., Beckett, D. J., Janmohamed, A., Cullingford, T. E., Smith, R. L., Shephard, E. A., Phillips, I. R. & Dolphin, C., 13 Nov 1998, In: Journal of Biological Chemistry. 273, 46, p. 30599-607 9 p.Research output: Contribution to journal › Article › peer-review
126 Citations (Scopus) -
1997
Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome
Dolphin, C. T., Janmohamed, A., Smith, R. L., Shephard, E. A., Phillips, I. R. & Dolphin, C., Dec 1997, In: Nature Genetics. 17, 4, p. 491-4 4 p.Research output: Contribution to journal › Article › peer-review
233 Citations (Scopus) -
Structural organization of the human flavin-containing monooxygenase 3 gene (FMO3), the favored candidate for fish-odor syndrome, determined directly from genomic DNA
Dolphin, C. T., Riley, J. H., Smith, R. L., Shephard, E. A., Phillips, I. R. & Dolphin, C., 1 Dec 1997, In: Genomics. 46, 2, p. 260-7 8 p.Research output: Contribution to journal › Article › peer-review
55 Citations (Scopus) -
1996
Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FM04
Dolphin, C. T., Cullingford, T. E., Shephard, E. A., Smith, R. L., Phillips, I. R. & Dolphin, C., 1 Feb 1996, In: European Journal of Biochemistry. 235, 3, p. 683-9 7 p.Research output: Contribution to journal › Article › peer-review
137 Citations (Scopus) -
Localization of human flavin-containing monooxygenase genes FMO2 and FMO5 to chromosome 1q
McCombie, R. R., Dolphin, C. T., Povey, S., Phillips, I. R. & Shephard, E. A., 15 Jun 1996, In: Genomics. 34, 3, p. 426-429 4 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
1995
The molecular biology of the flavin-containing monooxygenases of man
Phillips, I. R., Dolphin, C. T., Clair, P., Hadley, M. R., Hutt, A. J., McCombie, R. R., Smith, R. L. & Shephard, E. A., 28 Apr 1995, In: Chemico-Biological Interactions. 96, 1, p. 17-32 16 p.Research output: Contribution to journal › Article › peer-review
137 Citations (Scopus) -
1994
A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities
Lawton, M. P., Cashman, J. R., Cresteil, T., Dolphin, C. T., Elfarra, A. A., Hines, R. N., Hodgson, E., Kimura, T., Ozols, J. & Phillips, I. R., Jan 1994, In: Archives of biochemistry and biophysics. 308, 1, p. 254-7 4 p.Research output: Contribution to journal › Article › peer-review
198 Citations (Scopus) -
1993
Localization of genes encoding three distinct flavin-containing monooxygenases to human chromosome 1q
Shephard, E. A., Dolphin, C. T., Fox, M. F., Povey, S., Smith, R. & Phillips, I. R., Apr 1993, In: Genomics. 16, 1, p. 85-89 5 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
1992
Cloning, primary sequence and chromosomal localization of human FMO2, a new member of the flavin-containing mono-oxygenase family
Dolphin, C. T., Shephard, E. A., Povey, S., Smith, R. L., Phillips, I. R. & Dolphin, C., 1 Oct 1992, In: Biochemical Journal. 287 ( Pt 1), p. 261-7 7 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
1991
Cloning, primary sequence, and chromosomal mapping of a human flavin-containing monooxygenase (FMO1)
Dolphin, C., Shephard, E. A., Povey, S., Palmer, C. N., Ziegler, D. M., Ayesh, R., Smith, R. L., Phillips, I. R. & Dolphin, C., 5 Jul 1991, In: Journal of Biological Chemistry. 266, 19, p. 12379-85 7 p.Research output: Contribution to journal › Article › peer-review
96 Citations (Scopus) -
1988
The gene CYP3 encoding P450pcn1 (nifedipine oxidase) is tightly linked to the gene COL1A2 encoding collagen type 1 alpha on 7q21-q22.1
Brooks, B. A., McBride, O. W., Dolphin, C. T., Farrall, M., Scambler, P. J., Gonzalez, F. J. & Idle, J. R., Sept 1988, In: American Journal of Human Genetics. 43, 3, p. 280-4 5 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
The role of intestinal microflora in the formation of the methylthio adduct metabolites of paracetamol. Studies in neomycin-pretreated and germ-free mice
Mikov, M., Caldwell, J., Dolphin, C. T. & Smith, R. L., 15 Apr 1988, In: Biochemical Pharmacology. 37, 8, p. 1445-9 5 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
1987
Depression of oxidative metabolism of aspirin in mice via an interferon-associated mechanism in relation to Reye's syndrome
Dolphin, C. T., Caldwell, J. & Smith, R. L., Mar 1987, In: Journal of Pharmacy and Pharmacology. 39, 3, p. 228-30 3 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Effect of interferon synthesis upon the metabolism of [carboxyl-14C]-aspirin in the mouse
Dolphin, C. T., Caldwell, J. & Smith, R. L., 1 Aug 1987, In: Biochemical Pharmacology. 36, 15, p. 2437-42 6 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Effect of poly rI:rC treatment upon the metabolism of [14C]-paracetamol in the BALB/cJ mouse
Dolphin, C. T., Caldwell, J., Smith, R. L. & Dolphin, C., 15 Nov 1987, In: Biochemical Pharmacology. 36, 22, p. 3835-40 6 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)