Research output per year
Research output per year
Personal profile
Research interests
Cancer, kinase signalling pathways, PSKs, apoptosis, cytoskeleton, cell shape, migration, cell cycle and prostate
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Iggy Tavares is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies
Giacomini, C., Koo, C. Y., Yankova, N., Tavares, I. A. F., Wray, S., Noble, W. J., Hanger, D. P. & Morris, J. D. H., 7 May 2018, (E-pub ahead of print) In: Acta Neuropathologica Communications. 6, 37, p. 1-16 16 p., Acta Neuropathologica Communications 2018 6:37.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)304 Downloads (Pure) -
Targeting TAO kinases using a new inhibitor compound delays mitosis and induces mitotic cell death in centrosome amplified breast cancer cells
Koo, C. Y., Giacomini, C., Reyes-Corral, M., Olmos, Y., Tavares, I. A., Marson, C. M., Linardopoulos, S., Tutt, A. N. & Morris, J. D. H., 30 Nov 2017, In: MOLECULAR CANCER THERAPEUTICS. 16, 11, p. 2410-2421Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)242 Downloads (Pure) -
Prostate-derived Sterile 20-like Kinases (PSKs/TAOKs) Phosphorylate Tau and are Activated in Tangle-bearing Neurons in Alzheimer's Disease
Tavares, I. A., Touma, D., Lynham, S., Troakes, C., Schober, M., Causevic, M., Garg, R., Noble, W., Killick, R., Bodi, I., Hanger, D. P. & Morris, J. D. H., 24 May 2013, In: Journal of Biological Chemistry. 288, 21, p. 15418-15429 12 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
Prostate-derived sterile 20-like kinases (PSKs/TAOKs) are activated in mitosis and contribute to mitotic cell rounding and spindle positioning
Wojtala, R. L., Tavares, I. A., Morton, P. E., Valderrama, F., Thomas, N. S. B. & Morris, J. D. H., 26 Aug 2011, In: Journal of Biological Chemistry. 286, 34, p. 30161-30170 10 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Prostate-derived sterile 20-like kinase 1-alpha (PSK1-alpha ) induces apoptosis: JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing
Zihni, C., Mitsopoulos, C., Tavares, I. A., Baum, B., Ridley, A. J. & Morris, J. D. H., 2 Mar 2007, In: Journal of Biological Chemistry. 282, 9, p. 6484 - 6493 10 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus)
Projects
- 1 Finished
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Combining bioengineering, cell reprogramming and regeneration strategies for the treatment ofhuman kidney disease (NEPHROREG)
Sancho-Martinez, I. (Primary Investigator) & Tavares, I. (Co-Investigator)
1/01/2016 → 31/12/2020
Project: Research