Research output per year
Research output per year
Personal profile
Research interests
Normal Haemopoiesis and abnormalities in the myelodysplastic syndromes (MDS) and myeloid leukaemias; Cell cycle; Systems Biology analyses of protein interaction networks; Epigenetics (study of specific and genome-wide DNA CpG methylation, histone code and nucleosome positioning).
Research interests (short)
Cell cycle. Epigenetics. Systems Biology. Protein interaction networks.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, The role of polyribosomal messenger ribonucleoprotein complexes in protein synthesis, King's College London
Award Date: 1 Jan 1982
Master of Arts, University of Cambridge
Award Date: 1 Jan 1982
Bachelor of Science, University of Cambridge
Award Date: 1 Jan 1978
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Short loop functional commonality identified in leukaemia proteome highlights crucial protein sub-networks
Chung, S. S., Ng, J. C. F., Laddach, A., Thomas, N. S. B. & Fraternali, F., 1 Mar 2021, In: NAR Genomics and Bioinformatics. 3, 1, lqab010.Research output: Contribution to journal › Article › peer-review
Open Access -
Deep-phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment
Kordasti, S., Costantini, B., Seidl, T., Perez Abellan, P., Martinez Llordella, M., Mclornan, D., Diggins, K. E., Kulasekararaj, A., Benfatto, C., Feng, X., Smith, A., Mian, S. A., Melchiotti, R., De Rinaldis, E. D., Ellis, R., Petrov, N., Povoleri, G. A. M., Chung, S. S., Thomas, N. S. B. & Farzaneh, F. & 5 others, , 1 Sept 2016, In: Blood. 128, 9, p. 1193-1205 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile108 Citations (Scopus)339 Downloads (Pure) -
Bridging topological and functional information in protein interaction networks by short loops profiling
Chung, S. S., Pandini, A., Annibale, A., Coolen, A. C. C., Thomas, N. S. B. & Fraternali, F., 23 Feb 2015, In: Scientific Reports. 5, p. 8540Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells
Keohane, C., Kordasti, S., Seidl, T., Perez Abellan, P., Thomas, N. S. B., Harrison, C. N., Mclornan, D. P. & Mufti, G. J., 1 Oct 2015, In: British Journal of Haematology. 171, 1, p. 60-73Research output: Contribution to journal › Article › peer-review
78 Citations (Scopus) -
Potent and Selective Inhibitors of Histone Deacetylase-3 Containing Chiral Oxazoline Capping Groups and a N-(2-Aminophenyl)-benzamide Binding Unit
Marson, C. M., Matthews, C. J., Atkinson, S. J., Lamadema, N. & Thomas, N. S. B., 10 Sept 2015, In: Journal of Medicinal Chemistry. 58, 17, p. 6803-6818 16 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus)
Projects
- 74 Finished
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Systems biology approaches for drug discovery in acute myeloid leukaemia
Pandini, A. (Primary Investigator), Fraternali, F. (Co-Investigator) & Thomas, S. (Co-Investigator)
1/07/2014 → 30/06/2019
Project: Research
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Protein interaction abnormalities in leukaemia: effects of patient-specific genetic variation
Thomas, S. (Primary Investigator) & Fraternali, F. (Co-Investigator)
1/10/2013 → 30/09/2017
Project: Research
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Systems level understanding of cell size regulation
Csikasz-Nagy, A. (Primary Investigator) & Thomas, S. (Co-Investigator)
1/10/2013 → 30/09/2016
Project: Research
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Protein complexes in human T cells
Thomas, S. (Primary Investigator)
1/06/2013 → 31/05/2016
Project: Research
Activities
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I am organising a keynote talk at the same meeting
Thomas, S. (Organiser)
2008 → …Activity: Participating in or organising an event › Participation in conference
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I am organising a conference session on Expressing the Genome, Annual Meeting of the British Society for Haematology
Thomas, S. (Organiser)
2008 → …Activity: Participating in or organising an event › Participation in conference
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Organised conference session on Systems Biology, Annual Meeting of the British Society for Haematology, which has three Internationally renowned speakers, one from the US and two from the UK
Thomas, S. (Organiser)
2007 → …Activity: Participating in or organising an event › Participation in conference
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Chaired sessions at the Annual Meeting of the British Society for Haematology
Thomas, S. (Chair)
2007 → …Activity: Participating in or organising an event › Participation in conference
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Organising conference session on Epigenetis in Haematology, Annual Meeting of the British Society for Haematology, which had three Internationally renowned speakers from the UK
Thomas, S. (Organiser)
2006 → …Activity: Participating in or organising an event › Participation in conference
Prizes
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Elected to American Society for Haematology
Thomas, S. (Recipient), 2001
Prize: Election to learned society