Research output per year
Research output per year
Professor
I studied Biochemistry at University of Cambridge, followed by a PhD in Protein Design at the Department of Crystallography, Birkbeck College, University of London. Following a postdoctoral fellowship at the Protein Engineering Research Institute in Osaka under the EU scientific training program in Japan I returned to Cambridge in 1990 as a Zeneca Fellow at the MRC Centre for Protein Engineering to work on protein folding, classification and design. I co-founded SCOP (the Structural Classification of Proteins database) and developed algorithms to make protein structure predictions and assess their accuracy and to calibrate the reliability of sequence alignment methods. I was one of the most successful participants in the first CASP (Critical Assessment of Structure Prediction) competition in 1994 and a co-organiser of subsequent CASP competitions (CASP2-CASP7) until 2007. In 1997 I joined the Wellcome Trust Sanger Institute to become Head of Human Genome Analysis, where I was one of the organisers of the sequencing of the human genome. In 1999 I co-founded the Ensembl project to analysis, organise and provide access to the human genome. From 2007 I led the GENCODE project to annotate the structure of all human genes, initially as part of the ENCODE project. I was the Sanger Institute PI of the Genome Reference Consortium, which is responsible for reference genome sequences of human, mouse and zebrafish. I become Head of the Informatics division from 2007. After the announcement of the 100,000 genomes project 2012 I was seconded part time as specialist advisor for genomics to NHS England leading up to the creation of Genomics England. In October 2013 I was appointed Professor of Bioinformatics and Head of the Department of Medical & Molecular Genetics at King's College London and Director of Bioinformatics for King's Health Partners with a part time secondment as Head of Genome Analysis at Genomics England. In 2018 I was also appointed Associate Director (King's) for the Health Data Research UK (HDRUK) London Site.
Genomics & Bioinformatics, particularly around gene and regulatory annotation and predictive modelling; Human phenotype data, particularly around clinical data capture, organisation and research access; Genome Medicine, particularly the mainstreaming of whole genome sequencing into health systems for rare disease and cancer diagnostics, as well as enabling real time decision support for personalisation of treatment.
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, The Design, Expression and Characterisation of a Novel Protein, Birkbeck, University of London
Award Date: 1 Jan 1988
Bachelor of Arts, Natural Sciences (Biochemistry), University of Cambridge
Award Date: 1 Jan 1985
Head of Genome Analysis, Genomics England Ltd.
1 Oct 2013 → …
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Pallas, J. (Primary Investigator) & Hubbard, T. (Co-Investigator)
HDR UK Health Data Research UK
1/10/2018 → 31/03/2023
Project: Research
Hubbard, T. (Primary Investigator), Dobson, R. (Co-Investigator), Schnabel, J. (Co-Investigator), Hotopf, M. (Co-Investigator), Spector, T. (Co-Investigator), Simpson, M. (Co-Investigator), Lewis, C. (Co-Investigator), Curcin, V. (Co-Investigator), Stahl, D. (Co-Investigator), Landau, S. (Co-Investigator), Gulliford, M. (Co-Investigator), Stewart, R. (Co-Investigator), Wolfe, C. (Co-Investigator), Kelly, F. (Co-Investigator) & Beevers, S. (Co-Investigator)
HDR UK Health Data Research UK
1/04/2018 → 31/03/2023
Project: Research
Kere, J. (Primary Investigator), Hubbard, T. (Co-Investigator), Jungbluth, H. (Co-Investigator), Lewis, C. (Co-Investigator) & McGrath, J. (Co-Investigator)
1/01/2018 → 31/12/2019
Project: Research
Hodgkinson, A. (Primary Investigator) & Hubbard, T. (Co-Investigator)
1/12/2015 → 30/11/2018
Project: Research
Spencer, J. (Primary Investigator), Cason, J. (Co-Investigator), Cope, A. (Co-Investigator), Ehrlich, D. (Co-Investigator), Hayday, A. (Co-Investigator), Hubbard, T. (Co-Investigator), Mathew, C. (Co-Investigator), Mayr, M. (Co-Investigator) & Odell, E. (Co-Investigator)
1/08/2015 → 31/07/2019
Project: Research
Hubbard, T. (Member)
Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
Hubbard, T. (Member)
Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
Hubbard, T. (Member)
Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
Hubbard, T. (Member)
Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups
Hubbard, T. (Member)
Activity: Other › Types of External academic engagement - Contribution to the work of national or international committees and working groups