Depression in Primary Care Patients with Coronary Heart Disease: Baseline Findings from the UPBEAT UK Study

Paul Walters; Elizabeth A. Barley; Anthony Mann; Rachel Phillips; Andre Tylee

doi:10.1371/journal.pone.0098342

Depression in Primary Care Patients with Coronary Heart Disease: Baseline Findings from the UPBEAT UK Study

Paul Walters^*, Elizabeth A. Barley, Anthony Mann, Rachel Phillips, Andre Tylee

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

179 Downloads (Pure)

Abstract

Background: An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline.

Method: Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems.

Results: 803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98).

Conclusion: Problems living alone, chest pain and disability are important predictors of depression in this population.

Original language	English
Article number	e98342
Number of pages	7
Journal	PL o S One
Volume	9
Issue number	6
DOIs	https://doi.org/10.1371/journal.pone.0098342
Publication status	Published - 12 Jun 2014

Keywords

RANDOMIZED CONTROLLED-TRIAL
MAJOR DEPRESSION
GENERAL-PRACTITIONERS
MANAGING DEPRESSION
RISK-FACTOR
PREVALENCE
MORTALITY
ANXIETY

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A programme of research to develop and test stepped care for patients with depression and physical illness in primary care
Tylee, A. (Primary Investigator)
NIHR National Institute For Health & Care Research
1/09/2007 → 31/01/2016
Project: Research

27 Citations
2 Article

The UPBEAT Nurse-Delivered Personalized Care Intervention for People with Coronary Heart Disease Who Report Current Chest Pain and Depression: A Randomised Controlled Pilot Study
Barley, E. A., Walters, P., Haddad, M., Phillips, R., Achilla, E., McCrone, P., Van Marwijk, H., Mann, A. & Tylee, A., 5 Jun 2014, In: PL o S One . 9, 6, 14 p., e98704.
Research output: Contribution to journal › Article › peer-review

Open Access
35 Citations (Scopus)
UPBEAT study patients' perceptions of the effect of coronary heart disease on their lives: a cross-sectional sub-study
Smith, A., Fortune, Z., Phillips, R., Walters, P., Lee, G. A., Mann, A., Tylee, A. & Barley, E. A., 2014, (E-pub ahead of print) In: International Journal of Nursing Studies. N/A, N/A, p. N/A 25 p., N/A.
Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus)

1 Downloads (Pure)

Cite this

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title = "Depression in Primary Care Patients with Coronary Heart Disease: Baseline Findings from the UPBEAT UK Study",

abstract = "Background: An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline. Method: Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems. Results: 803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98). Conclusion: Problems living alone, chest pain and disability are important predictors of depression in this population.",

keywords = "RANDOMIZED CONTROLLED-TRIAL, MAJOR DEPRESSION, GENERAL-PRACTITIONERS, MANAGING DEPRESSION, RISK-FACTOR, PREVALENCE, MORTALITY, ANXIETY",

author = "Paul Walters and Barley, {Elizabeth A.} and Anthony Mann and Rachel Phillips and Andre Tylee",

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journal = "PL o S One ",

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AU - Mann, Anthony

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AU - Tylee, Andre

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N2 - Background: An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline. Method: Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems. Results: 803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98). Conclusion: Problems living alone, chest pain and disability are important predictors of depression in this population.

AB - Background: An association between depression and coronary heart disease is now accepted but there has been little primary care research on this topic. The UPBEAT-UK studies are centred on a cohort of primary patients with coronary heart disease assessed every six months for up to four years. The aim of this research was to determine the prevalence and associations of depression in this cohort at baseline. Method: Participants with coronary heart disease were recruited from general practice registers and assessed for cardiac symptoms, depression, quality of life and social problems. Results: 803 people participated. 42% had a documented history of myocardial infarction, 54% a diagnosis of ischaemic heart disease or angina. 44% still experienced chest pain. 7% had an ICD-10 defined depressive disorder. Factors independently associated with this diagnosis were problems living alone (OR 5.49, 95% CI 2.11-13.30), problems carrying out usual activities (OR 3.71, 95% CI 1.93-7.14), experiencing chest pain (OR 3.27, 95% CI 1.58-6.76), other pains or discomfort (OR 3.39, 95% CI 1.42-8.10), younger age (OR 0.95 per year 95% CI 0.92-0.98). Conclusion: Problems living alone, chest pain and disability are important predictors of depression in this population.

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KW - GENERAL-PRACTITIONERS

KW - MANAGING DEPRESSION

KW - RISK-FACTOR

KW - PREVALENCE

KW - MORTALITY

KW - ANXIETY

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Depression in Primary Care Patients with Coronary Heart Disease: Baseline Findings from the UPBEAT UK Study

Abstract

Keywords

Access to Document

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Projects

A programme of research to develop and test stepped care for patients with depression and physical illness in primary care

Research output

The UPBEAT Nurse-Delivered Personalized Care Intervention for People with Coronary Heart Disease Who Report Current Chest Pain and Depression: A Randomised Controlled Pilot Study

UPBEAT study patients' perceptions of the effect of coronary heart disease on their lives: a cross-sectional sub-study

Cite this