Detection of toxigenic Clostridium difficile in diarrheal stools by rapid real-time polymerase chain reaction

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Abstract

The Cepheid Xpert polymerase chain reaction assay (Sunnyvale, CA) had a sensitivity of 100%, specificity of 96.7%, and positive and negative predictive values of 90.5% and 100%, respectively, compared with toxigenic culture for the laboratory diagnosis of Clostridium difficile in diarrheal stool samples. This test appears to be a significant improvement to poorly performing enzyme immunoassays. (C) 2010 Elsevier Inc. All rights reserved.
Original languageEnglish
Pages (from-to)304 - 307
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume67
Issue number3
DOIs
Publication statusPublished - Jul 2010

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