Disproportionate body composition and perinatal outcome in large-for-gestational-age infants to mothers with type 1 diabetes

Objective To determine if disproportionate body composition is a risk factor for perinatal complications in large-for-gestational-age infants born to mothers with type 1 diabetes. Design Population-based cohort study. Setting Data from the Swedish Medical Birth Registry from 1998 to 2007. Population National cohort of 3517 infants born to mothers with type 1 diabetes. Only singletons with gestational age 32-43 weeks were included. Methods Large for gestational age (LGA) was defined as birthweight > 90th centile and appropriate for gestational age (AGA) as birthweight between 10th and 90th centiles. Disproportionate (D) infants were defined as having a ponderal index [PI: calculated as birthweight in grams/(length in cm) 3 > 90th centile] and proportionate (P) as PI