Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI

J M McDonnell; A J Beavil; G A Mackay; A J Henry; J P Cook; H J Gould; B J Sutton

Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI

J M McDonnell, A J Beavil, G A Mackay, A J Henry, J P Cook, H J Gould, B J Sutton

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Original language	English
Pages (from-to)	387-92
Number of pages	6
Journal	Biochemical Society Transactions
Volume	25
Issue number	2
Publication status	Published - May 1997

Keywords

Amino Acid Sequence
Animals
Binding Sites
Drug Design
Humans
Immunoglobulin E
Kinetics
Models, Structural
Mutagenesis, Site-Directed
Oligopeptides
Point Mutation
Protein Structure, Secondary
Receptors, IgE
Recombinant Proteins

Cite this

@article{21e0bffb26b6471bb9a33357335df4cf,

title = "Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI",

keywords = "Amino Acid Sequence, Animals, Binding Sites, Drug Design, Humans, Immunoglobulin E, Kinetics, Models, Structural, Mutagenesis, Site-Directed, Oligopeptides, Point Mutation, Protein Structure, Secondary, Receptors, IgE, Recombinant Proteins",

author = "McDonnell, {J M} and Beavil, {A J} and Mackay, {G A} and Henry, {A J} and Cook, {J P} and Gould, {H J} and Sutton, {B J}",

year = "1997",

month = may,

language = "English",

volume = "25",

pages = "387--92",

journal = "Biochemical Society Transactions",

issn = "0300-5127",

publisher = "Portland Press Ltd.",

number = "2",

}

TY - JOUR

T1 - Structure-based design of peptides that inhibit IgE binding to its high-affinity receptor Fc epsilon RI

AU - McDonnell, J M

AU - Beavil, A J

AU - Mackay, G A

AU - Henry, A J

AU - Cook, J P

AU - Gould, H J

AU - Sutton, B J

PY - 1997/5

Y1 - 1997/5

KW - Amino Acid Sequence

KW - Animals

KW - Binding Sites

KW - Drug Design

KW - Humans

KW - Immunoglobulin E

KW - Kinetics

KW - Models, Structural

KW - Mutagenesis, Site-Directed

KW - Oligopeptides

KW - Point Mutation

KW - Protein Structure, Secondary

KW - Receptors, IgE

KW - Recombinant Proteins

M3 - Article

C2 - 9191123

SN - 0300-5127

VL - 25

SP - 387

EP - 392

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

IS - 2

ER -