Total synthesis of (+/-)-aspercyclide A and its C19 methyl ether

James L. Carr; Daniel A. Offermann; Mary D. Holdom; Philip Dusart; Andrew J. P. White; Andrew J. Beavil; Robin J. Leatherbarrow; Stephen D. Lindell; Brian J. Sutton; Alan C. Spivey

doi:10.1039/b923528k

Total synthesis of (+/-)-aspercyclide A and its C19 methyl ether

James L. Carr, Daniel A. Offermann, Mary D. Holdom, Philip Dusart, Andrew J. P. White, Andrew J. Beavil, Robin J. Leatherbarrow, Stephen D. Lindell, Brian J. Sutton, Alan C. Spivey

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.

Original language	English
Pages (from-to)	1824 - 1826
Number of pages	3
Journal	CHEMICAL COMMUNICATIONS- ROYAL SOCIETY OF CHEMISTRY
Volume	46
Issue number	11
DOIs	https://doi.org/10.1039/b923528k
Publication status	Published - 2010

Access to Document

10.1039/b923528k

Cite this

@article{5a646c570a4a4a5ca7471045b69845b2,

title = "Total synthesis of (+/-)-aspercyclide A and its C19 methyl ether",

abstract = "The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.",

author = "Carr, {James L.} and Offermann, {Daniel A.} and Holdom, {Mary D.} and Philip Dusart and White, {Andrew J. P.} and Beavil, {Andrew J.} and Leatherbarrow, {Robin J.} and Lindell, {Stephen D.} and Sutton, {Brian J.} and Spivey, {Alan C.}",

year = "2010",

doi = "10.1039/b923528k",

language = "English",

volume = "46",

pages = "1824 -- 1826",

journal = "CHEMICAL COMMUNICATIONS- ROYAL SOCIETY OF CHEMISTRY",

publisher = "ROYAL SOC CHEMISTRY",

number = "11",

}

TY - JOUR

T1 - Total synthesis of (+/-)-aspercyclide A and its C19 methyl ether

AU - Carr, James L.

AU - Offermann, Daniel A.

AU - Holdom, Mary D.

AU - Dusart, Philip

AU - White, Andrew J. P.

AU - Beavil, Andrew J.

AU - Leatherbarrow, Robin J.

AU - Lindell, Stephen D.

AU - Sutton, Brian J.

AU - Spivey, Alan C.

PY - 2010

Y1 - 2010

N2 - The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.

AB - The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.

U2 - 10.1039/b923528k

DO - 10.1039/b923528k

M3 - Article

VL - 46

SP - 1824

EP - 1826

JO - CHEMICAL COMMUNICATIONS- ROYAL SOCIETY OF CHEMISTRY

JF - CHEMICAL COMMUNICATIONS- ROYAL SOCIETY OF CHEMISTRY

IS - 11

ER -

Total synthesis of (+/-)-aspercyclide A and its C19 methyl ether

Abstract

Access to Document

Fingerprint

Cite this