Universal tradeoff relation between speed, uncertainty, and dissipation in nonequilibrium stationary states

We derive universal thermodynamic inequalities that bound from below the moments of first-passage times of stochastic currents in nonequilibrium stationary states of Markov jump processes in the limit where the two thresholds that define the first-passage problem are large. These inequalities describe a tradeoff between speed, uncertainty, and dissipation in nonequilibrium processes, which are quantified, respectively, with the moments of the first-passage times of stochastic currents, the splitting probability of the first-passage problem, and the mean entropy production rate. Near equilibrium, the inequalities imply that mean first-passage times are lower bounded by the Van't Hoff-Arrhenius law, whereas far from thermal equilibrium the bounds describe a universal speed limit for rate processes. When the current is proportional to the stochastic entropy production, then the bounds are equalities, a remarkable property that follows from the fact that the exponentiated negative entropy production is a martingale.