Wolfson SPaRC

Projects

Projects per year 1994 2008 2009 2010 2012 2013 2014 2015 2016 2017 2030

• 2 Not started
• 40 Active
• 681 Finished

Projects per year

Search results

• Finished

  Investigating the role of the AMY1 receptor activation and sex hormones in CGRP release and expression in the trigeminovascular system

  Holland, P. (Primary Investigator)

  International Headache Society

  1/10/2023 → 30/09/2024

  Project: Research

• A multiphoton confocal microscope for deep tissue imaging in live organism

  Denk, F. (Primary Investigator), Bafadhel, M. (Co-Investigator), Bannister, K. (Co-Investigator), Bradbury, E. (Co-Investigator), Cleary, S. (Co-Investigator), Ivetic, A. (Co-Investigator), Levitt, J. (Co-Investigator), Parsons, M. (Co-Investigator), Pitchford, S. (Co-Investigator), Shaw, T. (Co-Investigator), Stramer, B. (Co-Investigator) & Warnatsch, A. (Co-Investigator)

  BBSRC Biotechnology and Biological Sciences Research Council

  1/08/2023 → 31/07/2024

  Project: Research

• Multi-modal dissection of neural circuits in health and disease

  Petrinovic, M.-M. (Primary Investigator), Andreae, L. (Co-Investigator), Bradbury, E. (Co-Investigator), Cash, D. (Co-Investigator), Cooke, S. (Co-Investigator), Delogu, A. (Co-Investigator), Fanto, M. (Co-Investigator), Ingham, N. (Co-Investigator), Rosenzweig, I. (Co-Investigator), Steel, K. (Co-Investigator), Warren, P. (Co-Investigator) & Xie, Y. (Co-Investigator)

  MRC Medical Research Council

  1/07/2023 → 30/06/2024

  Project: Research

• Kisspeptin as a sexually dimorphic novel therapeutic target for migraine.

  Holland, P. (Primary Investigator)

  Migraine Trust

  26/04/2023 → 30/11/2024

  Project: Research

• Estrogen-dependent sensitization of trigeminal neuropeptide signalling: interplay of migraine and temporomandibular joint disorder

  Holland, P. (Primary Investigator)

  Migraine Trust

  1/04/2023 → 30/11/2024

  Project: Research

• Validating neuro-navigated TMS stimulation in SCI patients: a feasibility study towards a gene therapy for SCI.

  Ahmed, A. (Primary Investigator) & Bradbury, E. (Co-Investigator)

  AO Foundation

  1/09/2022 → 30/04/2024

  Project: Research

• Expanding the populations for the identification of genes and variants imparting susceptibility to age-related hearing loss using data from the All of Us Research Program

  Steel, K. (Primary Investigator)

  NIH National Institutes of Health

  1/09/2022 → 31/08/2024

  Project: Research

• Using human live neural tissue to study the repair potential of endogenous neural stem cells

  Ahmed, A. (Primary Investigator)

  Royal College of Surgeons of England

  5/05/2022 → 4/04/2023

  Project: Research

• Investigating the somatosensory phenotype of people with Parkinson's disease

  Bannister, K. (Primary Investigator), Duty, S. (Co-Investigator), McMahon, S. (Co-Investigator) & Ray Chaudhuri, K. (Co-Investigator)

  Parkinson's UK

  15/09/2021 → 17/03/2024

  Project: Research

• Crosstalk between Sex Hormones and Amylin Signaling in the Trigeminovascular System.

  Hoffmann, J. (Primary Investigator)

  International Headache Society

  1/04/2021 → 30/09/2022

  Project: Research

• UKRI CoA: Recovery of normal breathing after chronic paralysis

  Warren, P. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  15/03/2021 → 24/09/2021

  Project: Research

• UKRI CoA: A phase 1 trial of a retinoic acid receptor beta agonist for the treatment of spinal cord injury

  Corcoran, J. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/01/2021 → 30/09/2021

  Project: Research

• Versailles Saint Quentin University - Secondment - McMahon

  McMahon, S. (Primary Investigator)

  UVSQ Versailles Saint-Quentin-en-Yvelines University

  1/12/2020 → 31/08/2021

  Project: Research

• UKRI CoA: Latent enhancers - a novel mechanism for pain chronification?

  Denk, F. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  22/11/2020 → 30/09/2021

  Project: Research

• UKRI CoA: Identification of novel bioactive mediators of tissue scarring, inflammation and extracellular matrix remodeling after spinal cord injury

  Bradbury, E. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/11/2020 → 30/09/2021

  Project: Research

• Regulated chondroitinase gene therapy for restoring upper limb and hand function in chronic cervical spinal cord injuries

  Bradbury, E. (Primary Investigator)

  Wings for Life - Spinal Cord Research Foundation

  1/10/2020 → 30/09/2022

  Project: Research

• UKRI CoA: Neurotrophic growth factors co-crystals for disease modifying therapy of Parkinson's disease

  Duty, S. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/09/2020 → 18/12/2020

  Project: Research

• Alzheimer’s Research UK King’s College London Network Centre Grant

  Bateman, J. (Primary Investigator), Aarsland, D. (Co-Investigator), Cash, D. (Co-Investigator), Fanto, M. (Co-Investigator), Giese, P. (Co-Investigator), Hanger, D. (Co-Investigator), Hirth, F. (Co-Investigator), Malcangio, M. (Co-Investigator), Miller, C. (Co-Investigator), Mitchell, J. (Co-Investigator), Mondal, M. (Co-Investigator), Noble, W. (Co-Investigator), Parsons, R. (Co-Investigator), Ruepp, M.-D. (Co-Investigator), Serrano Navacerrada, M. E. (Co-Investigator), So, P.-W. (Co-Investigator), Sreedharan, J. (Co-Investigator), Troakes, C. (Co-Investigator), Vagnoni, A. (Co-Investigator), Vance, C. (Co-Investigator), Vernon, A. (Co-Investigator) & academic, A. (Co-Investigator)

  Alzheimer's Research UK

  1/09/2020 → 30/09/2022

  Project: Research

• UKRI CoA: Functional investigations of enteroendocrine cell signalling in the intestine.

  Cox, H. (Primary Investigator)

  EPSRC Engineering and Physical Sciences Research Council

  1/07/2020 → 31/07/2021

  Project: Research

• Role of Rbfox1 in development of osteoarthritis pain: advancing mechanistic studies towards better-quality drug discovery

  Baron, O. (Primary Investigator), Denk, F. (Co-Investigator) & McMahon, S. (Co-Investigator)

  Versus Arthritis

  1/05/2020 → 11/03/2023

  Project: Research

• JPNDORGANOID: Multicellular organoids: modelling, mechanisms and therapy development for C9ORF72-associated neurodegeneration

  Hamilton-Whitaker, N. (Primary Investigator)

  MRC Medical Research Council

  1/03/2020 → 28/02/2024

  Project: Research

• MICA: Exosomes and microRNAs regulate neuro-immune interactions in chronic pain

  Malcangio, M. (Primary Investigator) & Chambers, D. (Co-Investigator)

  MRC Medical Research Council

  22/01/2020 → 21/01/2023

  Project: Research

• G protein-coupled receptor (GPCR) signaling in the mouse and human gastrointestinal (GI) tract.

  Cox, H. (Primary Investigator)

  Heptares Therapeutics Limited

  1/10/2019 → 30/09/2023

  Project: Research

• Manipulation of monocytes/macrophages for the control of arthritis pain using pro-resolving lipid mediators and blockade of CX3CR1 receptor

  Malcangio, M. (Primary Investigator)

  Arthritis Research UK

  30/09/2019 → 29/09/2022

  Project: Research

• Cerebrospinal fluid - a window into how our nervous system processes pain

  Denk, F. (Primary Investigator)

  Pain Relief Foundation

  1/09/2019 → 31/08/2022

  Project: Research

• Recovery of normal breathing after chronic paralysis

  Warren, P. (Primary Investigator)

  MRC Medical Research Council

  1/08/2019 → 31/01/2023

  Project: Research

• Delayed, subcutaneous neurotrophin-3 infusion improves recovery after stroke: mechanisms of recovery, automation of testing and markerless kinematics

  Moon, L. (Primary Investigator)

  MRC Medical Research Council

  1/08/2019 → 30/04/2023

  Project: Research

• Novel chemical approaches for specific targeting of CSPGs to restore function after SCI

  Bradbury, E. (Primary Investigator)

  Craig H. Neilsen Foundation

  31/07/2019 → 30/07/2023

  Project: Research

• Validation of HCN2 ion channels as targets for treatment of tinnitus

  McNaughton, P. (Primary Investigator)

  Action on Hearing Loss

  1/07/2019 → 31/12/2023

  Project: Research

• Cerebrospinal fluid – a window into how our brain processes pain?

  Denk, F. (Primary Investigator)

  Rosetrees Trust

  31/05/2019 → 1/03/2023

  Project: Research

• Defining descending modulatory pathways that regulate spinal nociceptive processing

  Bannister, K. (Primary Investigator)

  Academy of Medical Sciences

  15/04/2019 → 13/01/2022

  Project: Research

• Novel regenerative therapies for restoring sensory function after spinal cord injury

  Bradbury, E. (Primary Investigator)

  International Spinal Research Trust

  1/04/2019 → 30/06/2023

  Project: Research

• Exploration of lipidomics as a diagnostic tool for different forms of hearing loss

  Steel, K. (Primary Investigator) & Martelletti, E. (Co-Investigator)

  Action on Hearing Loss

  1/04/2019 → 30/09/2020

  Project: Research

• Neurotrophic growth factors co-crystals for disease modifying therapy of Parkinson's disease

  Duty, S. (Primary Investigator)

  Innovate UK

  1/03/2019 → 31/08/2020

  Project: Research

• Satellite glial cells in neuropathic pain

  McMahon, S. (Primary Investigator), Denk, F. (Co-Investigator) & Jager, S. B. (Primary Investigator)

  Lundbeck Foundation

  1/02/2019 → 31/01/2022

  Project: Research

• Pain evoked by passive transfer of IgG from fibromyalgia patients to mice

  Andersson, D. (Primary Investigator) & Bevan, S. (Co-Investigator)

  MRC Medical Research Council

  1/02/2019 → 31/12/2022

  Project: Research

  • Syndrome 100%
  • Patient 80%
  • Disease 45%
  • Symptom 45%
  • Intravenous Immunoglobulin 22%

• Boosting endogenous fibroblast growth factor 20 levels in the nigrostriatal tract to achieve neuroprotection and repair in Parkinson's disease

  Duty, S. (Primary Investigator)

  Parkinson's UK

  19/01/2019 → 19/09/2021

  Project: Research

• Development of Link_TSG6 as a novel disease-modifying protein biological for osteoarthritis with analgesic effects: pre-clinical evaluation to facilitate commercial partnering and clinical trials

  Bevan, S. (Primary Investigator)

  Arthritis Research UK

  1/01/2019 → 31/12/2019

  Project: Research

• BonePainII: A European Training Network to Combat Bone Pain

  McMahon, S. (Primary Investigator)

  EC European Commission

  1/01/2019 → 31/12/2022

  Project: Research

• Dissecting neural networks with optogenetic functional MRI (0pto-fMRI)

  Williams, S. (Primary Investigator), Petrinovic, M.-M. (Co-Investigator), Cash, D. (Co-Investigator), Cooke, S. (Co-Investigator), Bradbury, E. (Co-Investigator), Modinos, G. (Co-Investigator), Rosenzweig, I. (Co-Investigator), Tricklebank, M. (Co-Investigator), Marin, O. (Co-Investigator) & Goadsby, P. (Co-Investigator)

  Wellcome Trust

  1/01/2019 → 31/12/2023

  Project: Research

• HCN2 ion channels: a novel target for treatment of migraine

  McNaughton, P. (Primary Investigator)

  Brain Research UK

  1/12/2018 → 30/11/2020

  Project: Research

• Understanding the immune changes involved in the link between childhood trauma and adolescent depression

  Mondelli, V. (Primary Investigator), Barker, E. (Co-Investigator), Pariante, C. (Co-Investigator), Taams, L. (Co-Investigator), Denk, F. (Co-Investigator) & Vernon, A. (Co-Investigator)

  Medical Research Foundation

  1/12/2018 → 31/05/2020

  Project: Research

• TRP channels and white matter function in health and disease

  Hamilton-Whitaker, N. (Primary Investigator)

  MRC Medical Research Council

  1/12/2018 → 1/12/2022

  Project: Research

• Neuronal basis of pain produced by passive transfer of Fibromyalgia from patient to mouse

  Andersson, D. (Primary Investigator)

  Pain Relief Foundation

  1/10/2018 → 30/09/2019

  Project: Research

  • Satellite Glial Cell 100%
  • Titer 100%
  • Macrophage 100%
  • Spinal Cord 100%
  • Neuron 36%

• TOBeATPAIN: Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

  Malcangio, M. (Primary Investigator), Duty, S. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Ray Chaudhuri, K. (Co-Investigator)

  EC European Commission

  1/08/2018 → 31/07/2022

  Project: Research

• Drosophila model for muscular pain

  Baron, O. (Primary Investigator), Bateman, J. (Co-Investigator) & McMahon, S. (Co-Investigator)

  NC3Rs National Centre for the Replacement, Refinement and Reduction of Animals in Research

  1/06/2018 → 31/10/2022

  Project: Research

• Environmental enrichment-dependent neuronal activity pathways for axonal regeneration and recovery after spinal cord injury

  Moon, L. (Primary Investigator)

  MRC Medical Research Council

  1/06/2018 → 31/05/2021

  Project: Research

• Does fatty acid accumulation lead to TRPA1-mediated myelin damage?

  Hamilton-Whitaker, N. (Primary Investigator) & Doherty, P. (Co-Investigator)

  ELA European Leukodystrophy Association

  2/04/2018 → 1/04/2019

  Project: Research

• Understanding the mechanisms underlying progressive hearing loss associated with MIR96 mutations

  Steel, K. (Primary Investigator) & Lewis, M. (Co-Investigator)

  Action on Hearing Loss

  1/04/2018 → 31/03/2022

  Project: Research

• IMI-PainCare: Improving the care of patients suffering from acute or chronic pain

  McMahon, S. (Primary Investigator)

  EC European Commission

  1/04/2018 → 31/03/2023

  Project: Research