Research output per year
Research output per year
Personal profile
Research interests
Include the use of imaging to:
- Elucidate the neurobiology of epilepsy
- Work towards the noninvasive determination of epileptogenic areas during the presurgical workup
- Determine normal and abnormal patterns of brain changes over time, including in the neurodegenerative diseases (e.g. Alzheimer's disease)
- Automatically classify medical images
- Interest in imaging methodology, including the development of simultaneous MRI-PET.
Biographical details
Alexander Hammers; a Neurologist with a particular interest in epilepsy, is Professor of Imaging and Neuroscience and Head of the King’s College London & Guy’s and St Thomas’ PET Centre at St Thomas’ Hospital. He also serves as Deputy Head of School, School of Biomedical Engineering and Imaging Sciences.
He obtained an MD from the RWTH Aachen, Germany, in MR imaging of the hippocampus and a PhD from the University of London in PET investigations in focal epilepsy.
His research area is medical imaging, in particular functional neuroimaging with quantified Positron Emission Tomography (PET) to understand mechanisms of neurological disease. Another area is structural neuroimaging using Magnetic Resonance Imaging (MRI) and anatomical segmentation using a large manually annotated brain atlas database which his group has created over the past decade. The main areas of application of his research are the epilepsies and neurodegenerative diseases. The ultimate goal is to benefit individual patients through the clinical application of neuroscience, e.g. through classification with machine-learning techniques, or the combination of MRI and PET.
He is affiliated with several professional organisations, has won several distinctions, teaches regularly, and reviews frequently for numerous journals and grant-giving bodies. He is an author on about 200 articles, conference proceedings, and book chapters (WoS h index 44, Google Scholar 53).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Courage in decision-making: A mixed-methods study of COVID-19 vaccine uptake in women of reproductive age in the UK
Magee, L., Brown, J. R. B., Bowyer, V., Horgan, G., Boulding, H., Khalil, A., Cheetham, N., Harvey, N., The CSSB Study Group, The RESILIENT Study Group, Mistry, H., Sudre, C. H., Silverio, S. A., von Dadelszen, P. & Duncan, E., 18 Apr 2024, In: Vaccines. 12, 4, p. 1-16 440.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)57 Downloads (Pure) -
Deep Convolutional Backbone Comparison for Automated PET Image Quality Assessment
Hopson, J., Flaus, A., McGinnity, C., Neji, R., Reader, A. & Hammers, A., 3 Aug 2024, (Accepted/In press) In: IEEE Transactions on Radiation and Plasma Medical Sciences.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Downloads (Pure) -
EANM practice guidelines for an appropriate use of PET and SPECT for patients with epilepsy
Traub-Weidinger, T., Arbizu, J., Barthel, H., Boellaard, R., Borgwardt, L., Brendel, M., Cecchin, D., Chassoux, F., Fraioli, F., Garibotto, V., Guedj, E., Hammers, A., Law, I., Morbelli, S., Tolboom, N., Van Weehaeghe, D., Verger, A., Van Paesschen, W., von Oertzen, T. J. & Zucchetta, P. & 1 others, , Jun 2024, In: European Journal of Nuclear Medicine and Molecular Imaging. 51, 7, p. 1891-1908 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Generative-Model-Based Fully 3D PET Image Reconstruction by Conditional Diffusion Sampling
Webber, G., Mizuno, Y., Howes, O., Hammers, A., King, A. & Reader, A., 25 Sept 2024, In: 2024 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD).Research output: Contribution to journal › Conference paper › peer-review
Open Access -
Multi-Subject Image Synthesis as a Generative Prior for Single-Subject PET Image Reconstruction
Webber, G., Mizuno, Y., Howes, O., Hammers, A., King, A. & Reader, A., 25 Sept 2024, In: 2024 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector Conference (RTSD).Research output: Contribution to journal › Conference paper › peer-review
Open Access
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National Total Body PET Centre
Hammers, A. (Primary Investigator), Barrington, S. (Co-Investigator), Blower, P. (Co-Investigator), Cook, G. (Co-Investigator), Gee, T. (Co-Investigator), Marsden, P. (Co-Investigator), Modat, M. (Co-Investigator), Nazir, M. (Co-Investigator), Ourselin, S. (Co-Investigator), Razavi, R. (Co-Investigator), Reader, A. (Co-Investigator) & Terry, S. (Co-Investigator)
1/10/2023 → 30/09/2030
Project: Research
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CARL: A multi-user radiochemical synthesis facility for molecular imaging research
Gee, T. (Primary Investigator), Blower, P. (Co-Investigator), Blower, J. (Co-Investigator), Hammers, A. (Co-Investigator) & Nielsen, K. (Co-Investigator)
EPSRC Engineering and Physical Sciences Research Council
1/07/2022 → 30/06/2025
Project: Research
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Next generation imaging with Total Body Positron Emission Tomography for whole body organ perfusion
Nazir, M. (Primary Investigator), Cook, G. (Co-Investigator), Hammers, A. (Co-Investigator), Lilburn, D. (Co-Investigator), Marsden, P. (Co-Investigator) & Subesinghe, M. (Co-Investigator)
3/02/2025 → 2/02/2028
Project: Research
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Wellcome/EPSRC Centre for Medical Engineering Extension
Ourselin, S. (Primary Investigator), Barker, G. (Co-Investigator), Barnes, A. (Co-Investigator), Barrington, S. (Co-Investigator), Bergeles, C. (Co-Investigator), Bishop, M. (Co-Investigator), Blower, P. (Co-Investigator), Booth, T. (Co-Investigator), Botnar, R. (Co-Investigator), Cardoso, J. (Co-Investigator), Carmichael, D. (Co-Investigator), Chiribiri, A. (Co-Investigator), Clough, R. (Co-Investigator), Cook, G. (Co-Investigator), Counsell, S. (Co-Investigator), Dasgupta, P. (Co-Investigator), De Vecchi, A. (Co-Investigator), De Vita, E. (Co-Investigator), Edwards, D. (Co-Investigator), Goh, V. (Co-Investigator), Hajnal, J. (Co-Investigator), Hammers, A. (Co-Investigator), Hutter, J. (Co-Investigator), Ipek, O. (Co-Investigator), King, A. (Co-Investigator), Lamata de la Orden, P. (Co-Investigator), Liu, H. (Co-Investigator), Malik, S. (Co-Investigator), Marsden, P. (Co-Investigator), Modat, M. (Co-Investigator), Niederer, S. (Co-Investigator), Razavi, R. (Co-Investigator), Reader, A. (Co-Investigator), Rhode, K. (Co-Investigator), Roujol, S. (Co-Investigator), Rutherford, M. (Co-Investigator), Shapey, J. (Co-Investigator), Sparks, R. (Co-Investigator), T. M. de Rosales, R. (Co-Investigator), Terry, S. (Co-Investigator), Tournier, J.-D. (Co-Investigator), Vercauteren, T. (Co-Investigator), Williams, S. (Co-Investigator), Xia, W. (Co-Investigator), Young, A. (Co-Investigator) & academic, A. (Co-Investigator)
28/04/2022 → 27/10/2024
Project: Research
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Inflammation in tuberous sclerosis as a potential marker of epileptogenicity: a [18F]DPA-714 and elastography PET-MR study
Hammers, A. (Primary Investigator), McGinnity, C. (Co-Investigator), Sinkus, R. (Co-Investigator) & Turkheimer, F. (Co-Investigator)
1/10/2017 → 31/03/2019
Project: Research
Datasets
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Dataset used in paper ‘Evaluation of [13N]ammonia positron emission tomography as a potential method for quantifying glutamine synthetase activity in the human brain.’ (Egerton A and Dunn JT et al 2020)
Dunn, J., Egerton, A., Gee, A. & Hammers, A., King's College London, 20 Nov 2020
DOI: 10.18742/rdm01-667, https://kcl.figshare.com/articles/dataset/Dataset_used_in_paper_Evaluation_of_13N_ammonia_positron_emission_tomography_as_a_potential_method_for_quantifying_glutamine_synthetase_activity_in_the_human_brain_Egerton_A_and_Dunn_JT_et_al_2020_/16473936
Dataset