Research output per year
Research output per year
SE1 9RT
United Kingdom
Our research focuses on characterisation of G-protein coupled receptors (GPCRs) (the largest family of transmembrane signalling molecules) and their role in immune reactions leading to chronic inflammatory diseases, such as bronchial asthma and allergic diseases. Although, GPCRs are targets for more than 30% of all approved drugs, the expression and function of many of those receptors are incompletely characterized, and many remain orphans (without known ligands). The last years have seen remarkable advances in structural and functional biology of GPCRs that await now for translational medicine research. The understanding of GPCR responsiveness to lipid mediators such as leukotrienes, prostaglandins, lipoxins and lysophospholipids and their role in pathophysiology of asthma and allergic diseases is still based on data obtained long time ago and often does not agree with current discoveries. Newly developed molecular and cellular biology methods allow us to re-evaluate tissue and cell type specific expression, signalling and function of GPCRs and to redefine their role in processes leading to airway inflammation, bronchoconstriction, hyperresponsiveness and airway remodelling. A better understanding of GPCR biology may lead to development of new therapies for asthma and allergy.
G-protein coupled receptors in immune response and respiratory diseases.
Editorial activity
Associate Editor – BMC Immunology (2012 - )
Editorial Board Member - Inflammation & Allergy – Drug Targets (2013 - )
Research organisations
Board member- Immunology Section, European Academy of Allergy and Clinical Immunology (2013-2015)(2015-2017)
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Doctor of Philosophy, Genetic predisposition for differential organ manifestation of atopic diseases, Medical University of Lodz
Award Date: 1 Jan 2000
Doctor of Medicine, Medical University of Lodz
Award Date: 1 Jan 1993
Principal Investigator, Asthma UK Centre in Allergic Mechanisms of Asthma
2009 → …
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Woszczek, G. (Primary Investigator) & Corrigan, C. (Co-Investigator)
23/08/2017 → 22/02/2022
Project: Research
Hawrylowicz, C. (Primary Investigator), Woszczek, G. (Co-Investigator), Santos, A. (Co-Investigator), Martinez Nunez, R. (Co-Investigator) & Beavil, A. (Co-Investigator)
8/08/2016 → 31/12/2021
Project: Research
Woszczek, G. (Primary Investigator) & Corrigan, C. (Co-Investigator)
7/12/2015 → 6/12/2018
Project: Research
Woszczek, G. (Primary Investigator) & Corrigan, C. (Co-Investigator)
1/05/2015 → 30/04/2016
Project: Research
Woszczek, G. (Primary Investigator)
1/09/2014 → 31/08/2015
Project: Research