Research output per year
Research output per year
Personal profile
Research interests
Ischaemic heart disease, with focus on biochemical and molecular aspects of post-translational regulation of protein function, ion dysregulation, contractile failure and infarction.
Research interests (short)
Molecular mechanisms and novel therapies for cardiac dysfunction in ischaemia and failure.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Science, University of Bath
Award Date: 1 Jan 2002
Doctor of Philosophy, University of Bath
Award Date: 1 Jan 1986
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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CureHeart wins Big Beat Challenge, a £30 million research award from the British Heart Foundation
Avkiran, M., 24 Sept 2022, (E-pub ahead of print) In: European Heart Journal. p. ehac510Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Phosphorylation at Serines 157 and 161 Is Necessary for Preserving Cardiac Expression Level and Functions of Sarcomeric Z-Disc Protein Telethonin
Lewis, H. R., Eminaga, S., Gautel, M. & Avkiran, M., 8 Sept 2021, In: Frontiers in Physiology. 12, 732020.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Quantitative analysis of the cardiac phosphoproteome in response to acute β‐adrenergic receptor stimulation in vivo
Güran, A., Ji, Y., Fang, P., Pan, K. T., Urlaub, H., Avkiran, M. & Lenz, C., 1 Nov 2021, In: International Journal of Molecular Sciences. 22, 22, 12584.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Cyclic AMP represses pathological MEF2 activation by myocyte-specific hypo-phosphorylation of HDAC5
He, T., Huang, J., Chen, L., Han, G., Stanmore, D., Krebs-Haupenthal, J., Avkiran, M., Hagenmüller, M. & Backs, J., Aug 2020, In: Journal of Molecular and Cellular Cardiology. 145, p. 88-98 11 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Getting your research funded (and other tips for early career cardiovascular investigators)
Avkiran, M., 1 Sept 2019, In: Cardiovascular Research. 115, 11, p. e111-e112Research output: Contribution to journal › Comment/debate › peer-review
1 Citation (Scopus)
Projects
- 34 Finished
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To what extent can PKD-induced phosphorylation of cardiac myofibrils correct the dysfunction of myofibril contraction in the failing human heart
Kentish, J. (Primary Investigator), Avkiran, M. (Co-Investigator) & Sun, Y.-B. (Co-Investigator)
1/03/2017 → 28/02/2019
Project: Research
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King’s NMR Facility for structural biology, metabolic profiling and drug discovery
Conte, M. (Primary Investigator), Avkiran, M. (Co-Investigator), Blower, P. (Co-Investigator), Dodding, M. (Co-Investigator), Eaton, P. (Co-Investigator), Gautel, M. (Co-Investigator), Irving, M. (Co-Investigator), Malim, M. (Co-Investigator), Marber, M. (Co-Investigator), Mayr, M. (Co-Investigator), McDonnell, J. (Co-Investigator), Otsu, K. (Co-Investigator), Pastore, A. (Co-Investigator), Pfuhl, M. (Co-Investigator), Poston, L. (Co-Investigator), Shah, A. (Co-Investigator), Shanahan, C. (Co-Investigator), Shattock, M. (Co-Investigator) & Williamson, C. (Co-Investigator)
BHF British Heart Foundation, Wellcome Trust
1/01/2017 → 31/12/2021
Project: Research
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Associate Medical Director Fund
Shah, A. (Primary Investigator) & Avkiran, M. (Co-Investigator)
1/12/2016 → 30/11/2019
Project: Research
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BHF 4-Year PhD Studentship Scheme
Avkiran, M. (Primary Investigator), Mayr, M. (Primary Investigator) & Shah, A. (Primary Investigator)
1/10/2016 → 30/09/2020
Project: Research
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Investigating the role of cardiac non-myocyte microRNAs in myocardial fibrosis and hypertrophy in hypertrophic cardiomyopathy
Eminaga, S. (Primary Investigator) & Avkiran, M. (Co-Investigator)
1/03/2016 → 31/03/2022
Project: Research
Activities
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The Journal of Physiology (Journal)
Avkiran, M. (Editorial board member)
2011 → …Activity: Publication peer-review and editorial work › Editorial activity
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Elect, International Society for Heart Research
Avkiran, M. (President)
2010 → 2013Activity: Other › Types of External academic engagement - Membership of external research organisation
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Consulting Editor, Journal of Molecular and Cellular Cardiology (Journal)
Avkiran, M. (Editorial board member)
2010 → …Activity: Publication peer-review and editorial work › Editorial activity
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Institute for Cardiovascular and Metabolic Research, University of Reading
Avkiran, M. (Advisor)
2009 → …Activity: Other › Types of Business and Community - Work on advisory panel to industry or government or non-government organisation
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External Advisory Panel, BHF 4-Year PhD Programme in Cardiovascular Sciences, University of Manchester
Avkiran, M. (Advisor)
2009 → …Activity: Other › Types of Business and Community - Work on advisory panel to industry or government or non-government organisation
Prizes
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Fellowship of the American Heart Association (FAHA)
Avkiran, M. (Recipient), 2001
Prize: Fellowship awarded competitively
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Fellowship of the International Society for Heart Research (FISHR)
Avkiran, M. (Recipient), 2004
Prize: Fellowship awarded competitively