Research output per year
Research output per year
- 19 results
Search results
-
2022
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types
Shireby, G., Dempster, E. L., Policicchio, S., Smith, R. G., Pishva, E., Chioza, B., Davies, J. P., Burrage, J., Lunnon, K., Seiler Vellame, D., Love, S., Thomas, A., Brookes, K., Morgan, K., Francis, P., Hannon, E. & Mill, J., 24 Sept 2022, (E-pub ahead of print) In: Nature Communications. 13, 1, 5620.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
2021
The histone modification H3K4me3 is altered at the ANK1 locus in Alzheimer's disease brain
Smith, A. R., Smith, R. G., Macdonald, R., Marzi, S. J., Burrage, J., Troakes, C., Al-Sarraj, S., Mill, J. & Lunnon, K., 1 Apr 2021, In: Future Science OA. 7, 4Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
2020
An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene
Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., Kłoszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Wahlund, L. O., Aarsland, D., Proitsi, P., Hodges, A., Lovestone, S., Newhouse, S. J., Dobson, R. J. B. & Mill, J. & 2 others, , Nov 2020, In: Neurobiology of Aging. 95, p. 26-45 20 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Citations (Scopus) -
Recalibrating the epigenetic clock: Implications for assessing biological age in the human cortex
Shireby, G. L., Davies, J. P., Francis, P. T., Burrage, J., Walker, E. M., Neilson, G. W. A., Dahir, A., Thomas, A. J., Love, S., Smith, R. G., Lunnon, K., Kumari, M., Schalkwyk, L. C., Morgan, K., Brookes, K., Hannon, E. & Mill, J., 1 Dec 2020, In: Brain. 143, 12, p. 3763-3775 13 p.Research output: Contribution to journal › Article › peer-review
Open Access97 Citations (Scopus) -
2019
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood
Lardenoije, R., Roubroeks, J. A. Y., Pishva, E., Leber, M., Wagner, H., Iatrou, A., Smith, A. R., Smith, R. G., Eijssen, L. M. T., Kleineidam, L., Kawalia, A., Hoffmann, P., Luck, T., Riedel-Heller, S., Jessen, F., Maier, W., Wagner, M., Hurlemann, R., Kenis, G. & Ali, M. & 9 others, , 27 Nov 2019, In: Clinical Epigenetics. 11, 1, 164.Research output: Contribution to journal › Article › peer-review
Open Access78 Citations (Scopus) -
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease
Smith, A. R., Smith, R. G., Pishva, E., Hannon, E., Roubroeks, J. A. Y., Burrage, J., Troakes, C., Al-Sarraj, S., Sloan, C., Mill, J., Van Den Hove, D. L. & Lunnon, K., 21 Mar 2019, In: Clinical Epigenetics. 11, 1, 52.Research output: Contribution to journal › Article › peer-review
Open Access77 Citations (Scopus) -
2018
A cross-brain-regions study of ANK1 DNA methylation in different neurodegenerative diseases
Smith, A. R., Smith, R. G., Burrage, J., Troakes, C., Al-Sarraj, S., Kalaria, R. N., Sloan, C., Robinson, A. C., Mill, J. & Lunnon, K., 13 Oct 2018, (E-pub ahead of print) In: Neurobiology of Aging. 74, p. 70-76Research output: Contribution to journal › Article › peer-review
Open AccessFile53 Citations (Scopus)177 Downloads (Pure) -
2016
Are Established Methods of Physiotherapeutic Management for Long-term Neurological Conditions Applicable to 'Orphan' Conditions such as Syringomyelia?
Smith, R., Jones, G., Curtis, A., Murphy, H. & Flint, G., Mar 2016, In: PHYSIOTHERAPY RESEARCH INTERNATIONAL. 21, 1, p. 4-21 18 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
DNA methylation and substance use risk: A prospective, genome-wide study spanning gestation to adolescence
Cecil, C. A. M., Walton, E., Smith, R. G., Viding, E., McCrory, E., Relton, C., Suderman, M., Pingault, J.-B., McArdle, W., Gaunt, T. R., Mill, J. & Barker, E. D., 2016, In: Translational psychiatry. 6, 12, p. 1-9 9 p., e976.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Citations (Scopus)274 Downloads (Pure) -
Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability
Cecil, C., Smith, R. G., Walton, E., Mill, J., McCrory, E. J. & Viding, E., 13 Sept 2016, (E-pub ahead of print) In: Journal of psychiatric research.Research output: Contribution to journal › Article › peer-review
Open AccessFile93 Citations (Scopus)868 Downloads (Pure) -
2014
Environmental risk, Oxytocin Receptor Gene (OXTR) methylation and youth callous-unemotional traits: a 13-year longitudinal study
Cecil, C. A. M., Lysenko, L. J., Jaffee, S. R., Pingault, J. B., Smith, R. G., Relton, C. L., Woodward, G., Mcardle, W., Mill, J. & Barker, E., 31 Oct 2014, In: Molecular Psychiatry. 19, 10, p. 1071-1077Research output: Contribution to journal › Article › peer-review
Open Access156 Citations (Scopus) -
Genetic differences in cytochrome P450 enzymes and antidepressant treatment response
Hodgson, K., Tansey, K., Dernovsek, M. Z., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Smith, R., Craig, I. W., Farmer, A. E., Aitchison, K. J., Belsy, S., Davis, O. S. P., Uher, R. & McGuffin, P., Feb 2014, In: Journal of Psychopharmacology. 28, 2, p. 133-141 9 p.Research output: Contribution to journal › Article › peer-review
76 Citations (Scopus) -
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
Lunnon, K., Smith, R., Hannon, E., De Jager, P. L., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., Condliffe, D., Harries, L. W., Katsel, P., Haroutunian, V., Kaminsky, Z., Joachim, C., Powell, J., Lovestone, S., Bennett, D. A. & Schalkwyk, L. C. & 1 others, , 1 Sept 2014, In: Nature Neuroscience. 17, 9, p. 1164-1170 7 p.Research output: Contribution to journal › Article › peer-review
Open Access418 Citations (Scopus) -
Transcriptomic changes in the frontal cortex associated with paternal age
Smith, R. G., Fernandes, C., Kember, R., Schalkwyk, L. C., Buxbaum, J., Reichenberg, A. & Mill, J., 23 Mar 2014, In: Molecular Autism. 5, 7 p., 24.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
2013
DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP
Powell, T., Smith, R. G., Hackinger, S., Schalkwyk, L. C., Uher, R., McGuffin, P., Mill, J. & Tansey, K. E., 1 Sept 2013, In: Translational psychiatry. 3, 9, e300.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Citations (Scopus)191 Downloads (Pure) -
2012
DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice
Pidsley, R., Fernandes, C., Viana, J., Paya-Cano, J. L., Liu, L., Smith, R. G., Schalkwyk, L. C. & Mill, J., 6 Dec 2012, In: Molecular Brain Research. 5, N/A, p. N/A 9 p., 42.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
The novel Jagged/1CD46 interaction: a prime target for immune modulation by viruses?
Lea, S. M., Sheppard, D., Whiteman, P., le Friec, G., Waddington, S. N., Smith, R., Melchionna, T., Kemper, C., McDonnell, J., Handford, P. A. & McDonnell, J., Sept 2012, In: Immunology. 137, p. 7-8 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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2011
Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project
Keers, R., Uher, R., Huezo-Diaz, P., Smith, R., Jaffee, S., Rietschel, M., Henigsberg, N., Kozel, D., Mors, O., Maier, W., Zobel, A., Hauser, J., Souery, D., Placentino, A., Larsen, E. R., Dmitrzak-Weglarz, M., Gupta, B., Hoda, F., Craig, I. & McGuffin, P. & 2 others, , Apr 2011, In: PHARMACOGENOMICS JOURNAL. 11, 2, p. 138 - 145 8 p.Research output: Contribution to journal › Article › peer-review
72 Citations (Scopus) -
2010
Allelic Skewing of DNA Methylation Is Widespread across the Genome
Schalkwyk, L. C., Meaburn, E. L., Smith, R., Dempster, E. L., Jeffries, A. R., Davies, M., Plomin, R. & Mill, J., 12 Feb 2010, In: American Journal of Human Genetics. 86, 2, p. 196 - 212 17 p.Research output: Contribution to journal › Article › peer-review
Open Access215 Citations (Scopus)