Research output per year
Research output per year
Personal profile
Research interests
Control of gene expression in the brain; functional analysis of genetic polymorphisms that are associated with behavioural disorders using in vitro methods.
Research interests (short)
Gene expression in the brain; genetic polymorphisms; vitro methods.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Ursula D'Souza is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
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Allele-specific expression of the serotonin transporter and its transcription factors following lamotrigine treatment in vitro
D'Souza, U. M., Powell-Smith, G., Haddley, K., Powell, T., Bubb, V. J., Price, T., McGuffin, P., Quinn, J. P. & Farmer, A. E., Jul 2013, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 162, 5, p. 474-483 10 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway
Powell, T., Tansey, K. E., Breen, G., Farmer, A. E., Craig, I. W., Uher, R., McGuffin, P., D'Souza, U. M. & Schalkwyk, L. C., Jul 2013, In: Journal of Psychopharmacology. 27, 7, p. 609-615 7 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response
Powell, T., Schalkwyk, L. C., Heffernan, A. L., Breen, G., Lawrence, T., Price, T., Farmer, A. E., Aitchison, K. J., Craig, I. W., Danese, A., Lewis, C., McGuffin, P., Uher, R., Tansey, K. E. & D'Souza, U. M., Sept 2013, In: European Neuropsychopharmacology. 23, 9, p. 1105-1114 10 p.Research output: Contribution to journal › Article › peer-review
68 Citations (Scopus) -
Housekeeping gene expression is affected by antidepressant treatment in a mouse fibroblast cell line
Sugden, K., Pariante, C. M., McGuffin, P., Aitchison, K. J. & D'Souza, U. M., Aug 2010, In: Journal of Psychopharmacology. 24, 8, p. 1253 - 1259 7 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Functional genetic polymorphisms in serotonin and dopamine gene systems and their significance in behavioural disorders
D'Souza, U. M. & Craig, I. W., 2008, SEROTONIN-DOPAMINE INTERACTION: EXPERIMENTAL EVIDENCE AND THERAPEUTIC RELEVANCE. AMSTERDAM: Elsevier Science Publishers B.V., p. 73-98 26 p.Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution
41 Citations (Scopus)
Projects
- 9 Finished
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MRC 2009 SGDP Centre - Timothy Powell
D'Souza, U. (Primary Investigator) & Farmer, A. (Co-Investigator)
1/10/2009 → 30/09/2013
Project: Research
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The functional role and treatment response of polymorphil markers within the D4 dopamine receptor locus
D'Souza, U. (Co-Investigator)
1/10/2008 → 30/09/2011
Project: Research
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Proposal Acronym "Tristan"; Partner KCL; Transcriptional regulation of dopamine + serotonin pathway genes + functional effects of polymorphisms in transcription factors associated with neuropsychiatric disorders
D'Souza, U. (Co-Investigator)
1/09/2008 → 31/08/2011
Project: Research
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Translational Research on comparison of Gene Expression Profiles in Brain Tissue versus Peripheral Blood cells
D'Souza, U. (Co-Investigator)
1/07/2007 → 30/06/2009
Project: Research
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Comparison of gene expression profiles in rat brain tissue versus peripheral blood lymphocytes
D'Souza, U. (Co-Investigator)
1/04/2006 → 1/04/2007
Project: Research