Determining the molecular mechanisms underlying IL-10 expression in human CD4+ T-cells following TNF blockade

Taams, Leonie (Primary Investigator)
Dionne, Marc (Co-Investigator)
Lavender, Paul (Co-Investigator)

Peter Gorer Department of Immunobiology

Project: Research

5 Article

5 results

2024
Identification of a transcription factor network regulating anti-TNF mediated IL10 expression in human CD4+ T cells
Povoleri, G., Ridley, M., Marrow, R., Lalnunhlimi, S., Ryan, S., Kelly, A., Lavender, P. & Taams, L., 27 Jul 2024, In: Discovery Immunology. 3, 1, kyae013.
Research output: Contribution to journal › Article › peer-review

Open Access
2021
miR-155 overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T cell activation
Olsson, B. A., Povoleri, G., Somma, D., Ridley, M., Rizou, T., Lalnunhlimi, S., Macdonald, L., Rajasekhar, M., Martinez Nunez, R., Kurowska-Stolarska, M. & Taams, L., 30 Nov 2021, (E-pub ahead of print) In: Clinical and Expentmental Immunology.
Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus)
2020
Anti-TNF treatment negatively regulates human CD4+ T-cell activation and maturation in vitro, but does not confer an anergic or suppressive phenotype
Povoleri, G. A. M., Lalnunhlimi, S., Steel, K. J. A., Agrawal, S., O'Byrne, A., Ridley, M., Kordasti, S., Frederiksen, K. S., Roberts, C. A. & Taams, L. S., Mar 2020, In: European Journal of Immunology. 50, 3, p. 445-458 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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19 Citations (Scopus)

163 Downloads (Pure)
IKZF3/AIOLOs is associated with but not ₊sufficient _{T cells} for the expression of IL-10 by CD4: IKZF3 is associated with IL-10+ CD4+ T cells
Ridley, M., Fleskens, V., Roberts, C., Lalnunhlimi, S., Asnesf, A., O'Byrne, A., Steel, K., Povoleri, G., Sumner, J., Lavender, P. & Taams, L., 1 Jun 2020, In: Journal of Immunology. 204, 11, p. 2940-2948 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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18 Citations (Scopus)

130 Downloads (Pure)
Polyfunctional, Proinflammatory, Tissue-Resident Memory Phenotype and Function of Synovial Interleukin-17A+CD8+ T Cells in Psoriatic Arthritis
Steel, K. J. A., Srenathan, U., Ridley, M. L., Durham, L., Wu, S. Y., Ryan, S., Hughes, C. D., Chan, E., Kirkham, B. & Taams, L., 31 Mar 2020, In: Arthritis & rheumatology. 72, 3, p. 435-447 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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82 Citations (Scopus)

346 Downloads (Pure)