TY - JOUR
T1 - Modifiable determinants of postpartum weight loss in women with obesity
T2 - A secondary analysis of the upbeat trial
AU - Dalrymple, Kathryn V.
AU - Uwhubetine, Onome
AU - Flynn, Angela C.
AU - Pasupathy, Dharmintra
AU - Briley, Annette L.
AU - Relph, Sophie A.
AU - Seed, Paul T.
AU - O’keeffe, Majella
AU - Poston, Lucilla
N1 - Funding Information:
Supported by the European Union’s Seventh Framework Programme (FP7/2007–2013), project Early Nutrition, grant agreement no. 289346, and the National Institute for Health Research (NIHR) (UK) Programme Grants for Applied Research Programme (RP-0407-10452). Support was also provided by the Chief Scientist Office Scotland, Guy’s and St Thomas’ Charity, and Tommy’s Charity (Registered charity no. 1060508). L.P., A.C.F., and A.L.B. are funded by Tommy’s Charity, and K.V.D. is supported by the British Heart Foundation (FS/17/71/32953). P), P.T.S. is partly funded by King’s Health Partners Institute of Women and Children’s Health (KHTommy’s, and ARC South London (NIHR). L.P. is an NIHR Senior Investigator Emeritus (NI-SI-0512-10104). S.R. is supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London (NIHR CLAHRC South London) at King’s College Hospital NHS Foundation Trust. Acknowledgments: We thank all staff in the UPBEAT consortium and we are most grateful to all the women and their children who took part in the UPBEAT study.
Funding Information:
Funding: Supported by the European Union’s Seventh Framework Programme (FP7/2007–2013), project Early Nutrition, grant agreement no. 289346, and the National Institute for Health Research (NIHR) (UK) Programme Grants for Applied Research Programme (RP-0407-10452). Support was also provided by the Chief Scientist Office Scotland, Guy’s and St Thomas’ Charity, and Tommy’s Charity (Registered charity no. 1060508). L.P., A.C.F., and A.L.B. are funded by Tommy’s Charity, and K.V.D. is supported by the British Heart Foundation (FS/17/71/32953). P.T.S. is partly funded by King’s Health Partners Institute of Women and Children’s Health (KHP), Tommy’s, and ARC South London (NIHR). L.P. is an NIHR Senior Investigator Emeritus (NI-SI-0512-10104). S.R. is supported by the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care South London (NIHR CLAHRC South London) at King’s College Hospital NHS Foundation Trust.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/6/9
Y1 - 2021/6/9
N2 - Pregnancy can alter a woman’s weight gain trajectory across the life course and contribute to the development of obesity through retention of weight gained during pregnancy. This study aimed to identify modifiable determinants associated with postpartum weight retention (PPWR; calculated by the difference in pre-pregnancy and 6 month postpartum weight) in 667 women with obesity from the UPBEAT study. We examined the relationship between PPWR and reported glycaemic load, energy intake, and smoking status in pregnancy, excessive gestational weight gain (GWG), mode of delivery, self-reported postpartum physical activity (low, moderate, and high), and mode of infant feeding (breast, formula, and mixed). At the 6 month visit, 48% (n = 320) of women were at or above pre-pregnancy weight. Overall, PPWR was negative (−0.06 kg (−42.0, 40.4)). Breastfeeding for ≥4 months, moderate or high levels of physical activity, and GWG ≤9 kg were associated with negative PPWR. These three determinants were combined to provide a modifiable factor score (range 0–3); for each added variable, a further reduction in PPWR of 3.0 kg (95% confidence interval 3.76, 2.25) occurred compared to women with no modifiable factors. This study identified three additive determinants of PPWR loss. These provide modifiable targets during pregnancy and the postnatal period to enable women with obesity to return to their pre-pregnancy weight.
AB - Pregnancy can alter a woman’s weight gain trajectory across the life course and contribute to the development of obesity through retention of weight gained during pregnancy. This study aimed to identify modifiable determinants associated with postpartum weight retention (PPWR; calculated by the difference in pre-pregnancy and 6 month postpartum weight) in 667 women with obesity from the UPBEAT study. We examined the relationship between PPWR and reported glycaemic load, energy intake, and smoking status in pregnancy, excessive gestational weight gain (GWG), mode of delivery, self-reported postpartum physical activity (low, moderate, and high), and mode of infant feeding (breast, formula, and mixed). At the 6 month visit, 48% (n = 320) of women were at or above pre-pregnancy weight. Overall, PPWR was negative (−0.06 kg (−42.0, 40.4)). Breastfeeding for ≥4 months, moderate or high levels of physical activity, and GWG ≤9 kg were associated with negative PPWR. These three determinants were combined to provide a modifiable factor score (range 0–3); for each added variable, a further reduction in PPWR of 3.0 kg (95% confidence interval 3.76, 2.25) occurred compared to women with no modifiable factors. This study identified three additive determinants of PPWR loss. These provide modifiable targets during pregnancy and the postnatal period to enable women with obesity to return to their pre-pregnancy weight.
KW - Interventions
KW - Maternal obesity
KW - Postpartum weight retention
KW - Pregnancy
KW - Public health
UR - http://www.scopus.com/inward/record.url?scp=85107431287&partnerID=8YFLogxK
U2 - 10.3390/nu13061979
DO - 10.3390/nu13061979
M3 - Article
C2 - 34207523
AN - SCOPUS:85107431287
SN - 2072-6643
VL - 13
JO - Nutrients
JF - Nutrients
IS - 6
M1 - 1979
ER -
