Thoracic Endovascular Aortic Repair (TEVAR) in Proximal (Type A) Aortic Dissection: Ready for a Broader Application?

Christoph A. Nienaber, Natzi Sakalihasan, Rachel E. Clough, Mohamed Aboukoura, Enrico Mancuso, James S.M. Yeh, Jean-Olivier Defraigne, Nick Cheshire, Ulrich Peter Rosendahl, Cesare Quarto, John Pepper

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Abstract

Objective

Thoracic endovascular aortic repair (TEVAR) has demonstrated encouraging results and is gaining increasing acceptance as a treatment option for aortic aneurysms and dissections. Yet, its role in managing proximal aortic pathologies is unknown - this is important because in proximal (Stanford type A) aortic dissections, 10-30% are not accepted for surgery, and 30-50% are technically amenable for TEVAR. We describe our case series of type A aortic dissections treated using TEVAR.
Methods

Between year 2009 and 2016, 12 patients with acute, subacute or chronic type A aortic dissection with the proximal entry tear located between the coronaries and brachiocephalic artery were treated with TEVAR at 3 centers. Various stent-graft configurations were used to seal the proximal entry tear in the ascending aorta under rapid pacing.
Results

12 patients (9 male, 3 female), mean age 81±7 years, EuroSCORE II 9.1±4.5, underwent TEVAR for the treatment of type A aortic dissection. Procedural success was achieved in 11/12 patients (91.7%). There was one intra-procedural death and one minor stroke. No additional deaths at 30 days. At 36 months, there were 4 further deaths (all from non-aortic causes). The mean survival of these 4 deceased was 23 months (range 15-36 months). Follow-up computed tomography demonstrated favorable aortic remodeling.
Conclusion

TEVAR is feasible and reveals promising early results in selected patients with type A aortic dissection who are poor candidates for surgical repair. The current iteration of stent-graft technology however needs to be adapted to the specific features of the ascending aorta.
Original languageEnglish
JournalJournal of Thoracic and Cardiovascular Surgery
Early online date29 Aug 2016
DOIs
Publication statusE-pub ahead of print - 29 Aug 2016

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