Research output per year
Research output per year
- 18 results
Search results
-
2023
Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels
Strydom, A., Aug 2023, In: EBioMedicine. 94, 104692.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Recording of intellectual disability in general hospitals in England 2006–2019: Cohort study using linked datasets
Sheehan, R., Mansour, H., Broadbent, M., Hassiotis, A., Mueller, C., Stewart, R., Strydom, A. & Sommerlad, A., Mar 2023, In: PLoS Medicine. 20, 3 March, e1004117.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
2022
A 12-week exercise programme has a positive effect on everyday executive function in young people with Down syndrome: a pilot non-randomised controlled trial
Shields, N., Mizzi, N., Buhlert-Smith, K., Strydom, A., Prendergast, L. & Hocking, D. R., Dec 2022, In: Journal of Intellectual Disability Research. 66, 12, p. 924-938Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Aggressive challenging behavior in adults with intellectual disability: An electronic register-based cohort study of clinical outcome and service use
Smith, J., Baksh, R. A., Hassiotis, A., Sheehan, R., Ke, C., Wong, T. L. B. & Strydom, A., 2 Nov 2022, In: European Psychiatry. 65, 1Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Susceptibility to COVID-19 Diagnosis in People with Down Syndrome Compared to the General Population: Matched-Cohort Study Using Primary Care Electronic Records in the UK
Baksh, R. A., Strydom, A., Pape, S. E., Chan, L. F. & Gulliford, M. C., Jun 2022, In: Journal of General Internal Medicine. 37, 8, p. 2009-2015 7 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
2021
A multicentre validation study of the diagnostic value of plasma neurofilament light
Ashton, N. J., Janelidze, S., Al Khleifat, A., Leuzy, A., van der Ende, E. L., Karikari, T. K., Benedet, A. L., Pascoal, T. A., Lleó, A., Parnetti, L., Galimberti, D., Bonanni, L., Pilotto, A., Padovani, A., Lycke, J., Novakova, L., Axelsson, M., Velayudhan, L., Rabinovici, G. D. & Miller, B. & 21 others, , 7 Jun 2021, In: Nature Communications. 12, 1, 3400.Research output: Contribution to journal › Article › peer-review
Open Access253 Citations (Scopus) -
A Phase II Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy, Safety, and Tolerability of Arbaclofen Administered for the Treatment of Social Function in Children and Adolescents With Autism Spectrum Disorders: Study Protocol for AIMS-2-TRIALS-CT1
AIMS-2-TRIALS-CT1 Group, 24 Aug 2021, In: Frontiers in Psychiatry. 12, 1 p., 701729.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
Covid-19 in children with down syndrome: Data from the trisomy 21 research society survey
MBBS FRCPCH DM on behalf of The Trisomy 21 Research Society COVID-19 Initiative Study Group, 1 Nov 2021, In: Journal of Clinical Medicine. 10, 21, 5125.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (Scopus) -
Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study
Carmona-Iragui, M., Alcolea, D., Barroeta, I., Videla, L., Muñoz, L., Van Pelt, K. L., Schmitt, F. A., Lightner, D. D., Koehl, L. M., Jicha, G., Sacco, S., Mircher, C., Pape, S. E., Hithersay, R., Clare, I. C. H., Holland, A. J., Nübling, G., Levin, J., Zaman, S. H. & Strydom, A. & 5 others, , Aug 2021, In: The Lancet Neurology. 20, 8, p. 605-614 10 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer’s disease
Baksh, A. & Strydom, A., 2 May 2021, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 13, 1, e12184.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)33 Downloads (Pure) -
The Association between Physical Activity and CAMDEX-DS Changes Prior to the Onset of Alzheimer's Disease in Down Syndrome
Pape, S. E., Baksh, R. A., Startin, C., Hamburg, S., Hithersay, R. & Strydom, A., May 2021, In: Journal of Clinical Medicine. 10, 9Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
The clinical and neuropathological features of sporadic (Late-onset) and genetic forms of alzheimer’s disease
Rujeedawa, T., Félez, E. C., Clare, I. C. H., Fortea, J., Strydom, A., Rebillat, A. S., Coppus, A., Levin, J. & Zaman, S. H., 1 Oct 2021, In: Journal of Clinical Medicine. 10, 19, 4582.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (Scopus) -
2019
Dynamic Causal Modeling of the Relationship between Cognition and Theta-alpha Oscillations in Adults with Down Syndrome
Hamburg, S., Rosch, R., Startin, C. M., Friston, K. J. & Strydom, A., 1 May 2019, In: Cerebral cortex (New York, N.Y. : 1991). 29, 5, p. 2279-2290 12 p., bhz043.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
2018
Alzheimer's disease in Down syndrome: An overlooked population for prevention trials
Strydom, A., Coppus, A., Blesa, R., Danek, A., Fortea, J., Hardy, J., Levin, J., Nuebling, G., Rebillat, A.-S., Ritchie, C., Van Duijn, C., Zaman, S. & Zetterberg, H., 13 Dec 2018, (E-pub ahead of print) In: Alzheimers & Dementia. 4, p. 703-713Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Citations (Scopus)181 Downloads (Pure) -
Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease
Mann, D. M. A., Davidson, Y. S., Robinson, A. C., Allen, N., Hashimoto, T., Richardson, A., Jones, M., Snowden, J. S., Pendleton, N., Potier, M. C., Laquerrière, A., Prasher, V., Iwatsubo, T. & Strydom, A., 16 May 2018, (E-pub ahead of print) In: Acta Neuropathologica. p. 1-19 19 p.Research output: Contribution to journal › Article › peer-review
Open Access46 Citations (Scopus) -
2017
Movement side effects of antipsychotic drugs in adults with and without intellectual disability: UK population-based cohort study
Sheehan, R., Horsfall, L., Strydom, A., Osborn, D., Walters, K. & Hassiotis, A., 3 Aug 2017, (E-pub ahead of print) In: BMJ Open.Research output: Contribution to journal › Article › peer-review
Open AccessFile68 Citations (Scopus)155 Downloads (Pure) -
2016
Intracerebral haemorrhage in Down syndrome: Protected or predisposed? [version 1; referees: 2 approved]
Buss, L., Fisher, E., Hardy, J., Nizetic, D., Groet, J., Pulford, L. & Strydom, A., 12 May 2016, (E-pub ahead of print) In: F1000Research. 5Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)143 Downloads (Pure) -
2015
Behavioural and psychological symptoms of dementia in Down syndrome: Early indicators of clinical Alzheimer's disease?
Dekker, A., Strydom, A., Coppus, A., Nizetic, D., Vermeiren, Y., Naude, P., Van Dam, D., Potier, M.-C., Fortea, J. & De Deyn, P., 1 Dec 2015, In: Cortex. 73, p. 36-61 26 p.Research output: Contribution to journal › Article › peer-review
65 Citations (Scopus)