Search results

• 2008

  Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

  Fisher, S. A., Tremelling, M., Anderson, C. A., Gwilliam, R., Bumpstead, S., Prescott, N. J., Nimmo, E. R., Massey, D., Berzuini, C., Johnson, C., Barrett, J. C., Cummings, F. R., Drummond, H., Lees, C. W., Onnie, C. M., Hanson, C. E., Blaszczyk, K., Inouye, M., Ewels, P. & Ravindrarajah, R. & 17 others, Keniry, A., Hunt, S., Carter, M., Watkins, N., Ouwehand, W., Lewis, C. M., Cardon, L., The Wellcome Trust Case Control Consortium, Lobo, A., Forbes, A., Sanderson, J., Jewell, D. P., Mansfield, J. C., Deloukas, P., Mathew, C. G., Parkes, M. & Satsangi, J., Jun 2008, In: Nature Genetics. 40, 6, p. 710-712 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetics 100%
  • Single Nucleotide Polymorphism 100%
  • NOD2 100%
  • ATG16L1 100%
  • IRGM 100%
  380 Citations (Scopus)

• Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

  Barrett, J. C., Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., Silverberg, M. S., Taylor, K. D., Barmada, M. M., Bitton, A., Dassopoulos, T., Datta, L. W., Green, T., Griffiths, A. M., Kistner, E. O., Murtha, M. T., Regueiro, M. D., Rotter, J. I. & Schumm, L. P. & 41 others, Steinhart, A. H., Targan, S. R., Xavier, R. J., Libioulle, C., Sandor, C., Lathrop, M., Belaiche, J., Dewit, O., Gut, I., Heath, S., Laukens, D., Mni, M., Rutgeerts, P., Van Gossum, A., Zelenika, D., Franchimont, D., Hugot, J. P., de Vos, M., Vermeire, S., Louis, E., Cardon, L. R., Anderson, C. A., Drummond, H., Nimmo, E., Ahmad, T., Prescott, N. J., Onnie, C. M., Fisher, S. A., Marchini, J., Ghori, J., Bumpstead, S., Gwilliam, R., Tremelling, M., Deloukas, P., Mansfield, J., Jewell, D., Satsangi, J., Mathew, C. G., Parkes, M., Georges, M. & Daly, M. J., Aug 2008, In: Nature Genetics. 40, 8, p. 955 - 962 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Discovery 100%
  2252 Citations (Scopus)
• 2007

  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

  The Wellcome Trust Case Control Consortium, 7 Jun 2007, In: Nature. 447, 7145, p. 661 - 678 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Disease 100%
  • Genome Wide Association Study 100%
  • Genotyping 33%
  • Human Genetics 33%
  • Gene 33%
  8096 Citations (Scopus)

• Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.

  Zeggini, E., Weedon, M., Lindgren, C., Frayling, T., Elliott, K., Lango, H., Timpson, N., Perry, J., Rayner, N., Freathy, R., Barrett, J., Shields, B., Morris, A., Ellard, S., Groves, C., Harries, L., Marchini, J., Owen, K., Knight, B. & Cardon, L. & 12 others, Walker, M., Hitman, G., Morris, A., Doney, A., Wellcome Trust Case Control Consortium (WTCCC), McCarthy, M., Hattersley, A., Fisher, S., Lewis, C., Onnie, C., Prescott, N. & Mathew, C., 1 Jun 2007, In: Science. 316, 5829, p. 1336 - 1341 6 p.

  Research output: Contribution to journal › Article › peer-review
  1874 Citations (Scopus)
• 2001

  Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

  Hampe, J., Cuthbert, A., Croucher, P. J. P., Mirza, M. M., Mascheretti, S., Fisher, S., Frenzel, H., King, K., Hasselmeyer, A., MacPherson, A. J. S., Bridger, S., van Deventer, S., Forbes, A., Nikolaus, S., Lennard-Jones, J. E., Foelsch, U. R., Krawczak, M., Lewis, C., Schreiber, S. & Mathew, C. G., 16 Jun 2001, In: The Lancet. 357, 9272, p. 1925 - 1928 4 p.

  Research output: Contribution to journal › Article › peer-review

  • NOD2 100%
  • Gene 100%
  • Gene Linkage 50%
  • Protein 25%
  • Candidate Gene 25%
  1037 Citations (Scopus)