Search results

• Finished

  A randomised controlled trial of community brief mentalization based therapy compared to psychiatric admission in borderline personality disorder : a study of clinical outcome and cost difference

  Boydell, J. (Primary Investigator), Goldsmith, K. (Co-Investigator), Moran, P. (Co-Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  15/01/2015 → 13/01/2017

  Project: Research

• Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA-AF)

  Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/01/2015 → 31/12/2019

  Project: Research

• NIHR Clinical Trials Fellowship

  Pickles, A. (Primary Investigator)

  1/01/2015 → 30/06/2015

  Project: Research

• StereoTactic radiotherapy for wet Age-Related macular degeneration (STAR): a randomised, double-masked, sham-controlled, clinical trial comparing low-voltage X-ray irradiation and as needed bevacizumab, with as needed bevacizumab monotherapy

  Jackson, T. (Primary Investigator), Kelly, J. (Co-Investigator), Murphy, C. (Co-Investigator), Peacock, J. (Co-Investigator), Pickles, A. (Co-Investigator) & Wang, Y. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/12/2014 → 31/10/2022

  Project: Research

• NIHR Clinical Trials Fellowship

  Maddocks, M. (Primary Investigator), Murphy, C. (Co-Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/11/2014 → 31/08/2015

  Project: Research

• A feasibility study to evaluate local heat preconditioning with respect to its effects on wound healing after reconstructive breast surgery in patients with breast cancer - a single blind randomised controlled trial

  Cornelius, V. (Primary Investigator), Kelly, J. (Co-Investigator), Murphy, C. (Co-Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  6/10/2014 → 5/10/2017

  Project: Research

• STRATA - Schizophrenia: Treatment Resistance and Therapeutic Advances

  Maccabe, J. (Primary Investigator), Barker, G. (Co-Investigator), Egerton, A. (Co-Investigator), Howes, O. (Co-Investigator), Kapur, S. (Co-Investigator), Lythgoe, D. (Co-Investigator), McCrone, P. (Co-Investigator), McGuire, P. (Co-Investigator), Murray, R. (Co-Investigator), Pickles, A. (Co-Investigator), Rose, D. (Co-Investigator) & Stone, J. (Co-Investigator)

  MRC Medical Research Council

  1/10/2014 → 31/12/2019

  Project: Research

• Building Resilience and Recovery through Enhancing Cognition and quality of Life in the early PSychosEs (ECLIPSE)

  Wykes, T. (Primary Investigator), Cella, M. (Co-Investigator), McCrone, P. (Co-Investigator), Pickles, A. (Co-Investigator), Reeder, C. (Co-Investigator), Rose, D. (Co-Investigator) & Taylor, M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2014 → 31/03/2021

  Project: Research

• Catheter Ablation Versus Thoracoscopic surgical Ablation in Long Standing Persistent atrial fibrillation 12/127/127

  Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator) & academic, A. (Co-Investigator)

  1/10/2014 → 30/09/2018

  Project: Research

• STRATA - Schizophrenia: Treatment Resistance and Therapeutic Advances

  Maccabe, J. (Primary Investigator), Barker, G. (Co-Investigator), Egerton, A. (Co-Investigator), Howes, O. (Co-Investigator), Kapur, S. (Co-Investigator), Lythgoe, D. (Co-Investigator), McCrone, P. (Co-Investigator), McGuire, P. (Co-Investigator), Murray, R. (Co-Investigator), Pickles, A. (Co-Investigator), Rose, D. (Co-Investigator) & Stone, J. (Co-Investigator)

  MRC Medical Research Council

  1/10/2014 → 30/09/2019

  Project: Research

• LEAVO - A Multicentre Phase III Double-masked Randomised Controlled Non-Inferiority Trial comparing the clinical and cost effectiveness of intravitreal therapy with ranibizumab (Lucentis) vs aflibercept (Eylea) vs bevacizumab (Avastin) for Macular Oedema due to Central Retinal Vein Occlusion (CRVO)

  Pickles, A. (Primary Investigator), Prevost, T. (Primary Investigator), Kelly, J. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/10/2014 → 30/09/2018

  Project: Research

• STRIVE - A multicentre randomiSed controlled TRial of IntraVEnous Immunoglobulin (IVIg) versus standard therapy for the treatment of transverse myelitis in adults and children

  Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator), McCrone, P. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2014 → 18/03/2016

  Project: Research

• Stratified Medicine in Mental Health with a primary focus on depression and anxiety, application to prospective and randomised data.

  Hellier, J. (Primary Investigator), Koukounari, A. (Co-Investigator) & Pickles, A. (Co-Investigator)

  1/09/2014 → 31/08/2017

  Project: Research

• Prenatal and infancy origins of biological and social-cognitive processes in disruptive behaviour problems in children aged 7 - 9 years

  Pickles, A. (Primary Investigator)

  MRC Medical Research Council

  1/08/2014 → 31/05/2018

  Project: Research

  • Disruptive Behavior 100%
  • Child 100%
  • Problem Behavior 100%
  • Infancy 100%
  • Cognitive Process 100%

• Transistioning to adulthood : A prospective longitudinal study

  Pickles, A. (Primary Investigator)

  1/07/2014 → 30/06/2019

  Project: Research

• Clinical Efficacy and Mechanistic Evaluation of Aflibercept for Proliferative Diabetic Retinopathy (CLARITY)

  Kelly, J. (Co-Investigator), Murphy, C. (Co-Investigator), Pickles, A. (Primary Investigator) & Prevost, T. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/07/2014 → 30/06/2017

  Project: Research

• Multivariate pattern analysis combined with neuroimaging as a test for treatment prediction and diagnostic classification in Attention Deficit Hyperactivity Disorder

  Rubia, K. (Primary Investigator), Brammer, M. (Co-Investigator), Curran, S. (Co-Investigator), Marquand, A. (Co-Investigator), Mehta, M. (Co-Investigator), Pickles, A. (Co-Investigator), Simonoff, E. (Co-Investigator) & Zelaya, F. (Co-Investigator)

  1/06/2014 → 1/06/2019

  Project: Research

• Improving outcomes for people with autism spectrum disorders by reducing mental health problems

  Simonoff, E. (Primary Investigator), Charman, T. (Co-Investigator), Knapp, M. (Co-Investigator), Murphy, D. (Co-Investigator), Pickles, A. (Co-Investigator) & Scott, S. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/05/2014 → 8/03/2021

  Project: Research

• Improving outcomes for people with autism spectrum disorders by reducing mental health problems

  Simonoff, E. (Primary Investigator), Charman, T. (Co-Investigator), Knapp, M. (Co-Investigator), Murphy, D. (Co-Investigator), Pickles, A. (Co-Investigator) & Scott, S. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/05/2014 → 30/04/2019

  Project: Research

• A cross syndrome approach to atypical development: Modelling development trajectories in autism spectrum disorder,attention deficit hyperactivity disorder and callous-unemotional traits.

  Bedford, R. (Primary Investigator) & Pickles, A. (Co-Investigator)

  Wellcome Trust

  1/05/2014 → 30/04/2018

  Project: Research

• Evaluation of the clinical and cost-effectiveness of Short-term Integrated Palliative Care Services (SIPC) to OPTimise CARE for people with advanced long term Neurological conditions (OPTCARE Neuro)

  Gao, W. (Primary Investigator), Higginson, I. (Primary Investigator), Al-Chalabi, A. (Co-Investigator), Evans, C. (Co-Investigator), Hotopf, M. (Co-Investigator), McCrone, P. (Co-Investigator), Murtagh, F. (Co-Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2014 → 31/01/2019

  Project: Research

• Evaluation of the clinical and cost-effectiveness of Short-term Integrated Palliative Care Services (SIPC) to OPTimise CARE for people with advanced long term Neurological conditions (OPTCARE Neuro)

  Pickles, A. (Primary Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2014 → 30/09/2017

  Project: Research

• Building resilience and recovery through enhancing cognition and quality of life in early psychoses (ECLIPSE)

  Wykes, T. (Primary Investigator), McCrone, P. (Co-Investigator), Pickles, A. (Co-Investigator), Reeder, C. (Co-Investigator), Rose, D. (Co-Investigator) & academic, A. (Co-Investigator)

  1/04/2014 → 1/04/2019

  Project: Research

• ASCOT: A randomised controlled trial of adjunctive intraocular and perioocular steroid (triamcinolone acetonide) versus standard treatment in eyes undergoing vitreoretinal surgery for open globe trauma

  Cornelius, V. (Primary Investigator), Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2014 → 31/12/2020

  Project: Research

• The Development of Social, Attention, and Perception Abilities in Typical and at-risk Infants.

  Charman, T. (Primary Investigator) & Pickles, A. (Co-Investigator)

  MRC Medical Research Council

  1/03/2014 → 30/11/2019

  Project: Research

• Recovery Colleges Characterisation and Testing (RECOLLECT study)

  Slade, M. (Primary Investigator), Dewey, M. (Co-Investigator), McCrone, P. (Co-Investigator), Pickles, A. (Co-Investigator), Price, J. (Co-Investigator) & academic, A. (Co-Investigator)

  1/01/2014 → 30/06/2016

  Project: Research

• A multicentre phase III randomised controlled single-masked clinical trial to test the clinical efficacy of light masks at preventing dark adaptation in the treatment of early diabetic macular oedema (CLEOPATRA)

  Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/01/2014 → 30/06/2017

  Project: Research

• The development of a self-management intervention for distress in people with multiple sclerosis within a stepped care framework : A proof of concept randomised controlled trial

  Chalder, T. (Primary Investigator), Brown, R. (Co-Investigator), David, A. (Co-Investigator), Hotopf, M. (Co-Investigator), McCrone, P. (Co-Investigator), Moss-Morris, R. (Co-Investigator), Pickles, A. (Co-Investigator) & Rayner, L. (Co-Investigator)

  1/01/2014 → 31/12/2015

  Project: Research

• A multicentre phase III randomised controlled single-masked clinical trial to test the clinical efficacy of light masks at preventing dark adaptation in the treatment of early diabetic macular oedema (CLEOPATRA)

  Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator) & Prevost, T. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/01/2014 → 30/06/2017

  Project: Research

• How far could widespread dissemination of parenting programmes improve child antisocial behaviour and reduce social inequalities

  Landau, S. (Primary Investigator), Pickles, A. (Co-Investigator) & Scott, S. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/11/2013 → 31/10/2015

  Project: Research

• Dissecting brain inflammation in depression : Integrating behaviour,PET,MRS,MRI,cytokines and transcriptomics

  Pariante, C. (Primary Investigator), Barker, G. (Co-Investigator), Cleare, A. (Co-Investigator), Dazzan, P. (Co-Investigator), Dobson, R. (Co-Investigator), Hayday, A. (Co-Investigator), Hotopf, M. (Co-Investigator), Howes, O. (Co-Investigator), Kapur, S. (Co-Investigator), Pickles, A. (Co-Investigator), Rabiner, E. (Co-Investigator), Taylor, M. (Co-Investigator), Turkheimer, F. (Co-Investigator) & Tylee, A. (Co-Investigator)

  1/10/2013 → 30/09/2016

  Project: Research

• Effectiveness and cost-effectiveness of perinatal mental health services

  Bick, D. (Primary Investigator), Howard, L. (Primary Investigator), Byford, S. (Co-Investigator), Hunter, M. (Co-Investigator), Morgan, C. (Co-Investigator), Pariante, C. (Co-Investigator), Pawlby, S. (Co-Investigator), Pickles, A. (Co-Investigator) & Rose, D. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/09/2013 → 30/09/2019

  Project: Research

• Improving measurement of patient outcomes - service user involvement

  Wykes, T. (Primary Investigator), Ennis, L. (Co-Investigator), McCrone, P. (Co-Investigator), Pickles, A. (Co-Investigator) & Rose, D. (Co-Investigator)

  1/09/2013 → 1/09/2016

  Project: Research

• ADHD, emotional dysregulation and response to Methylphenidate in prisoners with ADHD in local/remand UK prison

  Young, S. (Primary Investigator), Hellier, J. (Co-Investigator) & Pickles, A. (Co-Investigator)

  1/09/2013 → 31/08/2016

  Project: Research

• The neurobiological basis of Puerperal Psychosis : how multiple systems interact with brain vulnerability.

  Dazzan, P. (Primary Investigator), Clement, S. (Co-Investigator), Craig, M. (Co-Investigator), Howard, L. (Co-Investigator), Mehta, M. (Co-Investigator), Pariante, C. (Co-Investigator), Pickles, A. (Co-Investigator), Price, J. (Co-Investigator), Srivastava, D. (Co-Investigator) & Williams, S. (Co-Investigator)

  Medical Research Foundation

  1/09/2013 → 31/01/2017

  Project: Research

• Effectiveness and cost-effectiveness of perinatal mental health services (ESMI)

  Howard, L. (Primary Investigator), Bick, D. (Co-Investigator), Byford, S. (Co-Investigator), Hunter, M. (Co-Investigator), Morgan, C. (Co-Investigator), Pariante, C. (Co-Investigator), Pawlby, S. (Co-Investigator), Pickles, A. (Co-Investigator) & Rose, D. (Co-Investigator)

  DHSC Department of Health and Social Care

  1/09/2013 → 31/08/2018

  Project: Research

• Developing methods for understanding mechanism in complex interventions.

  Landau, S. (Primary Investigator), Pickles, A. (Co-Investigator) & Wykes, T. (Co-Investigator)

  MRC Medical Research Council

  30/06/2013 → 29/09/2016

  Project: Research

• A cluster randomised controlled trial of a behavioural change package to prevent hand dermatitis in nurses working in the National Health Service (the SCIN trial)

  Wright, A. (Primary Investigator), Kelly, J. (Co-Investigator), Koeser, L. (Co-Investigator), McCrone, P. (Co-Investigator), Murphy, C. (Co-Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/06/2013 → 31/05/2017

  Project: Research

• Penumbra and Recanalisation Acute Computed Tomography in Ischaemic Stroke Evaluation (PRACTISE)

  Kalra, L. (Primary Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/06/2013 → 30/11/2016

  Project: Research

• A cluster randomised controlled trial of a behavioural change package to prevent hand dermatitis in nurses working in the National Health Service

  Pickles, A. (Primary Investigator), Kelly, J. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/06/2013 → 31/05/2017

  Project: Research

• Improving outcomes in adults with epilepsy and intellectual disability: A cluster randomised controlled trial of nurse-led clinical management (N.B. Strategic uplift - Learning Disabilities)

  Pickles, A. (Primary Investigator), Murphy, C. (Co-Investigator) & Pennington, M. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2013 → 30/11/2015

  Project: Research

• Inference using calibration samples.

  Pickles, A. (Primary Investigator)

  MRC Medical Research Council

  1/04/2013 → 30/04/2014

  Project: Research

• EME Project : 12/66/15 - Clinical Efficacy and Mechanistic Evaluation of Aflibercept for proliferative diabetic retinopathy CLARITY trial

  Prevost, T. (Primary Investigator), Kelly, J. (Co-Investigator), Pickles, A. (Co-Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2013 → 31/03/2016

  Project: Research

• Improving outcomes in adults with epilepsy and intellectual disability: A cluster randomised controlled trial of nurse-led clinical management (N.B. Strategic uplift Learning Disabilities)

  Pickles, A. (Primary Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/04/2013 → 30/11/2015

  Project: Research

• Developing assertive outreach interventions across clinical boundaries to manage alcohol related frequent attenders of acute care (Acronym: CHAOS)

  Drummond, C. (Primary Investigator), Ashworth, M. (Co-Investigator), Gilburt, H. (Co-Investigator), Hotopf, M. (Co-Investigator), Pickles, A. (Co-Investigator) & Thornicroft, G. (Co-Investigator)

  1/04/2013 → 31/03/2018

  Project: Research

• Validating the Case Register Interactive Search (CRIS) system for large naturalistic treatment trials in youth: A two-phase study using Attention Deficit Hyperactivity Disorder (ADHD) as a model.

  Stringaris, A. (Primary Investigator), Goodman, R. (Co-Investigator), Pickles, A. (Co-Investigator) & Simonoff, E. (Co-Investigator)

  Guy's & St Thomas' Charity

  5/03/2013 → 31/12/2014

  Project: Research

• Prevention of major depression in at-risk adolescents: a pilot randomised screen-and-intervene program

  Smith, P. (Primary Investigator), Chadwick, P. (Co-Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/03/2013 → 31/08/2015

  Project: Research

• Does vertebral stenting prevent recurrent stroke in symptomatic vertebral artery stenosis: The Vertebral artery Ischaemia Stenting Trial (VIST)

  Murphy, C. (Primary Investigator) & Pickles, A. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  1/03/2013 → 28/02/2018

  Project: Research

• Low-dose Intravenous Immunoglobulin Treatment for Complex Regional Pain Syndrome (The LIPS Trial)

  Pickles, A. (Primary Investigator) & Murphy, C. (Co-Investigator)

  NIHR National Institute For Health & Care Research

  15/02/2013 → 31/07/2016

  Project: Research

• Pre-School autism intervention and autism development : A longitudinal follow up of the Preschool Autism Communication Trial (PACT)

  Charman, T. (Primary Investigator), Byford, S. (Co-Investigator) & Pickles, A. (Co-Investigator)

  MRC Medical Research Council

  1/02/2013 → 31/03/2015

  Project: Research