Frederic Geissmann

2022

RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients

The RA-MAP Consortium, Isaacs, J. D., Brockbank, S., Pedersen, A. W., Hilkens, C., Anderson, A., Stocks, P., Lendrem, D., Tarn, J., Smith, G. R., Allen, B., Casement, J., Diboll, J., Harry, R., Cooles, F. A. H., Cope, A. P., Simpson, G., Toward, R., Noble, H. & Parke, A. & 31 others, Wu, W., Clarke, F., Scott, D., Scott, I. C., Galloway, J., Lempp, H., Ibrahim, F., Schwank, S., Molyneux, G., Lazarov, T., Geissmann, F., Goodyear, C. S., McInnes, I. B., Donnelly, I., Gilmour, A., Virlan, A. T., Porter, D., Ponchel, F., Emery, P., El-Jawhari, J., Parmar, R., McDermott, M. F., Fisher, B. A., Young, S. P., Jones, P., Raza, K., Filer, A., Pitzalis, C., Barnes, M. R., Watson, D. S. & Henkin, R., Dec 2022, In: Scientific Data. 9, 1, 196.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Citations (Scopus)

2016

Development and function of tissue resident macrophages in mice

Kierdorf, K., Prinz, M., Geissmann, F. & Gomez Perdiguero, E., 29 Mar 2016, (E-pub ahead of print) In: Seminars in Immunology.

Research output: Contribution to journal › Article › peer-review

75 Citations (Scopus)

Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities

Bain, C. C., Hawley, C. A., Garner, H., Scott, C. L., Schridde, A., Steers, N. J., Mack, M., Joshi, A., Guilliams, M., Mowat, A. M. I., Geissmann, F. & Jenkins, S. J., 13 Jun 2016, In: Nature Communications. 7, 11852.

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Open Access

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244 Citations (Scopus)

172 Downloads (Pure)

Specification of tissue-resident macrophages during organogenesis

Mass, E., Ballesteros, I., Farlik, M., Halbritter, F., Günther, P., Crozet, L., Jacome-Galarza, C. E., Händler, K., Klughammer, J., Kobayashi, Y., Gomez Perdiguero, E., Schultze, J. L., Beyer, M., Bock, C. & Geissmann, F., 9 Sept 2016, In: Science (New York, N.Y.). 353, 6304

Research output: Contribution to journal › Article › peer-review

591 Citations (Scopus)

2015

Macrophage-Derived upd3 Cytokine Causes Impaired Glucose Homeostasis and Reduced Lifespan in Drosophila Fed a Lipid-Rich Diet

Woodcock, K. J., Kierdorf, K., Pouchelon, C. A., Vivancos, V., Dionne, M. S. & Geissmann, F., 20 Jan 2015, In: Immunity. 42, 1, p. 133-144 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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112 Citations (Scopus)

129 Downloads (Pure)

2014

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

Bain, C. C., Bravo-Blas, A., Scott, C. L., Gomez Perdiguero, E., Geissmann, F., Henri, S., Malissen, B., Osborne, L. C., Artis, D. & Mowat, A. M., Oct 2014, In: Nature Immunology. 15, 10, p. 929-937 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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843 Citations (Scopus)

169 Downloads (Pure)

Environment drives selection and function of enhancers controlling tissue-specific macrophage identities

Gosselin, D., Link, V. M., Romanoski, C. E., Fonseca, G. J., Eichenfield, D. Z., Spann, N. J., Stender, J. D., Chun, H. B., Garner, H., Geissmann, F. & Glass, C. K., 4 Dec 2014, In: Cell. 159, 6, p. 1327-1340 14 p.

Research output: Contribution to journal › Article › peer-review

972 Citations (Scopus)

TNF-alpha blockade induces IL-10 expression in human CD4+T cells

Evans, H. G., Roostalu, U., Walter, G. J., Gullick, N. J., Frederiksen, K. S., Roberts, C. A., Sumner, J., Baeten, D. L., Gerwien, J. G., Cope, A. P., Geissmann, F., Kirkham, B. & Taams, L. S., 4 Feb 2014, In: Nature Communications. 5, 1, 12 p., 3199.

Research output: Contribution to journal › Article › peer-review

99 Citations (Scopus)

2013

Fuz Mutant Mice Reveal Shared Mechanisms between Ciliopathies and FGF-Related Syndromes

Tabler, J. M., Barrell, W. B., Szabo-Rogers, H. L., Healy, C., Yeung, Y., Perdiguero, E. G., Schulz, C., Yannakoudakis, B. Z., Mesbahi, A., Wlodarczyk, B., Geissmann, F., Finnell, R. H., Wallingford, J. B. & Liu, K. J., 24 Jun 2013, In: Developmental Cell. 25, 6, p. 623-635 13 p.

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Open Access

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62 Citations (Scopus)

379 Downloads (Pure)

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

Kierdorf, K., Erny, D., Goldmann, T., Sander, V., Schulz, C., Perdiguero, E. G., Wieghofer, P., Heinrich, A., Riemke, P., Hoelscher, C., Mueller, D. N., Luckow, B., Brocker, T., Debowski, K., Fritz, G., Opdenakker, G., Diefenbach, A., Biber, K., Heikenwalder, M. & Geissmann, F. & 2 others, Rosenbauer, F. & Prinz, M., Mar 2013, In: Nature Neuroscience. 16, 3, p. 273-280 8 p.

Research output: Contribution to journal › Article › peer-review

1059 Citations (Scopus)

Nr4a1-Dependent Ly6C(low) Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

Carlin, L. M., Stamatiades, E. G., Auffray, C., Hanna, R. N., Glover, L., Vizcay-Barrena, G., Hedrick, C. C., Cook, H. T., Diebold, S. & Geissmann, F., 11 Apr 2013, In: Cell. 153, 2, p. 362-375 14 p.

Research output: Contribution to journal › Article › peer-review

584 Citations (Scopus)

2012

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

Schulz, C., Gomez Perdiguero, E., Chorro, L., Szabo-Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S. E. W., Pollard, J. W., Frampton, J., Liu, K. J. & Geissmann, F., 6 Apr 2012, In: Science. 336, 6077, p. 86-90 5 p.

Research output: Contribution to journal › Article › peer-review

1966 Citations (Scopus)

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

Schulz, C., Gomez Perdiguero, E., Chorro, L., Szabo Rogers, H., Cagnard, N., Kierdorf, K., Prinz, M., Wu, B., Jacobsen, S., Pollard, J., Frampton, J., Liu, K. & Geissmann, F., 6 Apr 2012, In: Science. 336, 6077, p. 86 - 90 5 p.

Research output: Contribution to journal › Article › peer-review

1966 Citations (Scopus)

NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis

Hanna, R. N., Shaked, I., Hubbeling, H. G., Punt, J. A., Wu, R., Herrley, E., Zaugg, C., Pei, H., Geissmann, F., Ley, K. & Hedrick, C. C., 3 Feb 2012, In: Circulation Research. 110, 3, p. 416 - U127 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

346 Citations (Scopus)

Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb

Etzrodt, M., Cortez-Retamozo, V., Newton, A., Zhao, J., Ng, A., Wildgruber, M., Romero, P., Wurdinger, T., Xavier, R., Geissmann, F., Meylan, E., Nahrendorf, M., Swirski, F. K., Baltimore, D., Weissleder, R. & Pittet, M. J., 19 Apr 2012, In: Plant Cell Reports. 1, 4, p. 317-324 8 p.

Research output: Contribution to journal › Article › peer-review

103 Citations (Scopus)

2010

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

Cros, J., Cagnard, N., Woollard, K., Patey, N., Zhang, S.-Y., Senechal, B., Puel, A., Biswas, S. K., Moshous, D., Picard, C., Jais, J.-P., D'Cruz, D., Casanova, J.-L., Trouillet, C. & Geissmann, F., Sept 2010, In: Immunity. 33, 3, p. 375 - 386 12 p.

Research output: Contribution to journal › Article › peer-review